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Jiantao Ma
National Institutes of Health
Framingham Heart StudyFramingham Risk ScoreEndocrinologyDiabetes mellitusMedicine
32Publications
12H-index
443Citations
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Publications 34
Newest
#1Irma Karabegović (Erasmus University Medical Center)H-Index: 1
#2Eliana Portilla-Fernandez (Erasmus University Medical Center)H-Index: 1
Last. Srikant Ambatipudi (UoB: University of Bristol)H-Index: 10
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Coffee and tea are extensively consumed beverages worldwide. Observational studies have shown contradictory findings for the association between consumption of these beverages and different health outcomes. Epigenetics is suggested as a mechanism mediating the effects of dietary and lifestyle factors on disease onset. We conducted epigenome-wide association studies (EWAS) on coffee and tea consumptions in 15,789 participants of European and African-American ancestries from 15 cohorts. EWAS meta-...
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#1Jiantao Ma (Tufts University)H-Index: 12
#2Sophia Lu (BU: Boston University)
Last. Douglas E. Levy (NIH: National Institutes of Health)H-Index: 200
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#1Casey M. Rebholz (Johns Hopkins University)H-Index: 18
#2Hyunju Kim (Johns Hopkins University)H-Index: 6
Last. Alice H. Lichtenstein (Tufts University)H-Index: 81
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Background: The Dietary Guidelines for Americans (DGAs) provide dietary recommendations for the general population with the intent of preventing chronic disease such as cardiovascular disease. An evaluation of whether updated versions of the DGAs accomplish this goal is lacking. Objective: The objective of this project was to determine whether updates to DGAs over time, reflected in subsequent versions of diet quality indices, strengthened the associations between diet quality and risk of cardio...
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#1Tianxiao Huan (NIH: National Institutes of Health)H-Index: 24
#2Roby Joehanes (NIH: National Institutes of Health)H-Index: 26
Last. Douglas E. Levy (NIH: National Institutes of Health)H-Index: 200
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Identifying methylation quantitative trait loci (meQTLs) and integrating them with disease-associated variants from genome-wide association studies (GWAS) may illuminate functional mechanisms underlying genetic variant-disease associations. Here, we perform GWAS of >415 thousand CpG methylation sites in whole blood from 4170 individuals and map 4.7 million cis- and 630 thousand trans-meQTL variants targeting >120 thousand CpGs. Independent replication is performed in 1347 participants from two s...
1 CitationsSource
#1Maura E Walker (BU: Boston University)
#2Vanessa Xanthakis (BU: Boston University)H-Index: 23
Last. Paul F. Jacques (Tufts University)H-Index: 100
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#1Jiantao Ma (Tufts University)H-Index: 12
#2Jana Nano (Erasmus University Medical Center)H-Index: 9
Last. Douglas E. Levy (NIH: National Institutes of Health)H-Index: 200
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Nonalcoholic fatty liver disease (NAFLD) is a risk factor for type 2 diabetes (T2D). We aimed to identify the peripheral blood DNA methylation signature of hepatic fat. We conducted epigenome-wide association studies of hepatic fat in 3,400 European ancestry (EA) participants and in 401 Hispanic ancestry and 724 African ancestry participants from four population-based cohort studies. Hepatic fat was measured using computed tomography or ultrasound imaging and DNA methylation was assessed at >400...
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#1Rachel Hennein (NIH: National Institutes of Health)H-Index: 2
#2Chunyu Liu (BU: Boston University)H-Index: 54
Last. Jiantao Ma (Tufts University)H-Index: 12
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#1Michelle T. Long (BU: Boston University)H-Index: 14
#2Ellen B. Gurary (BU: Boston University)H-Index: 4
Last. Rohit Loomba (UCSD: University of California, San Diego)H-Index: 58
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1 CitationsSource
#1Danielle E. Haslam (USDA: United States Department of Agriculture)H-Index: 3
#2Jiantao MaH-Index: 12
Last. Nicola M. McKeown (USDA: United States Department of Agriculture)H-Index: 36
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Abstract Sugar-sweetened beverages are a major source of added sugar in the diet. Fructose is a type of sugar suspected to be particularly harmful to health. In observational studies, individuals who consume more sugary beverages have greater visceral adipose tissue (VAT), which is fat around the liver and abdominal organs. VAT, as opposed to subcutaneous adipose tissue (SAT), is linked to higher risk of metabolic disease. Evidence from randomized controlled trials (RCT) suggests that excess sug...
Source
#1Michelle T. Long (BU: Boston University)H-Index: 14
#2Alison Pedley (MSD: Merck & Co.)H-Index: 17
Last. Emelia J. Benjamin (BU: Boston University)H-Index: 154
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1 CitationsSource
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