Match!
Qing Li
University of Bremen
17Publications
10H-index
390Citations
Publications 16
Newest
#1Jingfeng Li (University of Bremen)H-Index: 17
#2Qing Li (University of Bremen)H-Index: 10
Last.Colombi Ciacchi Lucio (University of Bremen)H-Index: 1
view all 5 authors...
Atomic-force-microscopy-based single-molecule force spectroscopy (AFM-SMFS) has become an important technique as the basis of novel, label-free biosensing strategies. In this work, we explored the possibility of using AFM-SMFS to detect the specific peptide cleavage activity by thrombin proteases. To achieve this aim, an oligopeptide with a sequence that is recognized and cleaved by thrombin was spanned between an AFM tip and a solid surface via a PEG-based linker system including the stable bio...
1 CitationsSource
#1Qing Li (University of Bremen)H-Index: 10
#2Gang Wei (University of Bremen)H-Index: 38
Single molecule force spectroscopy based on atomic force microscopy (AFM) is a simple and sensitive technique to probe molecular recognition forces. Here we demonstrate that visual color-intensity analysis of single molecule force mapping (SMFM) can be employed as a quick and convenient force-to-color detection towards the presence of various dissolved analytes in very low concentrations. To achieve this aim, analyte-specific single-strand DNA aptamers are first bound to an AFM tip. The measured...
1 CitationsSource
#1Yizhou Huang (Huada: Beijing University of Chemical Technology)H-Index: 2
#2Yazhou Tian (Huada: Beijing University of Chemical Technology)H-Index: 3
Last.Junying Zhang (Huada: Beijing University of Chemical Technology)H-Index: 15
view all 7 authors...
A series of epoxy systems with tunable rigid-flexibility were prepared by the curing reaction of bisphenol F diglycidyl (DGEBF), a single-ended amine with alkyl chains (n-butyl, octyl, dodecyl), 4,4′-diaminodiphenylmethane (DDM) and 4,4′-diaminodicyclohexylmethane (H-DDM). By means of adjusting the composition of the curing agent (the molar ratio between H-DDM and DDM), nano- and submicron-sized phase separations were observed by atomic force microscopy (AFM). And diffraction peaks were not obse...
7 CitationsSource
#1Qing Li (University of Bremen)H-Index: 10
#2Tong Zhang (UGA: University of Georgia)H-Index: 2
Last.Gang Wei (University of Bremen)H-Index: 38
view all 6 authors...
The interactions between biomolecules and material interfaces at the molecular level are complicated but very important for the development of materials science, nanotechnology, biophysics, biomedicine, and analytical science. Atomic force microscopy-based force spectroscopy (AFM-FS) is a useful technique for directly measuring the interactions between biomolecules and different material interfaces from the hard inorganic surfaces to the soft bio-substrates. In this review, we summarize recent s...
24 CitationsSource
#1Jingfeng Li (University of Bremen)H-Index: 17
#2Qing Li (University of Bremen)H-Index: 10
Last.Gang Wei (University of Bremen)H-Index: 38
view all 4 authors...
We demonstrate a simple force-based label-free strategy for the highly sensitive sensing of adenosine. An adenosine ssDNA aptamer was bound onto an atomic force microscopy (AFM) probe by covalent modification, and the molecular-interface adsorption force between the aptamer and a flat graphite surface was measured by single-molecule force spectroscopy (SMFS). In the presence of adenosine, the molecular recognition between adenosine and the aptamer resulted in the formation of a folded, hairpin-l...
9 CitationsSource
#1Qing Li (University of Bremen)H-Index: 10
#2Monika Michaelis (University of Bremen)H-Index: 2
Last.Lucio Colombi Ciacchi (University of Bremen)H-Index: 22
view all 4 authors...
We have developed a novel aptasensor based on single-molecule force spectroscopy (SMFS) capable of detecting mercury ions (Hg2+) with sub-nM sensitivity. The single-strand (ss) DNA aptamer used in this work is rich in thymine (T) and readily forms T–Hg2+–T complexes in the presence of Hg2+. The aptamer was conjugated to an atomic force microscope (AFM) probe, and the adhesion force between the probe and a flat graphite surface was measured by single-molecule force spectroscopy (SMFS). The presen...
17 CitationsSource
#1Panpan Zhang (Huada: Beijing University of Chemical Technology)H-Index: 13
#2Haixia Wang (Huada: Beijing University of Chemical Technology)H-Index: 9
Last.Zhiqiang Su (Huada: Beijing University of Chemical Technology)H-Index: 30
view all 8 authors...
Graphene and silver nanoparticles (AgNPs) are important building blocks for the synthesis of functional nanomaterials for bio-related applications. Here, we report a facile strategy to decorate AgNPs onto reduced graphene oxide (RGO) by the simultaneous reduction of silver ions and graphene oxide nanosheets within one system, and further to fabricate a dimension-adjustable RGO/AgNP multi-layered film by a thermal-driven self-assembly process. The structures of the fabricated RGO/AgNP hybrid film...
43 CitationsSource
#1Junwei Ding (Huada: Beijing University of Chemical Technology)H-Index: 7
#2Shiying Zhu (Huada: Beijing University of Chemical Technology)H-Index: 1
Last.Zhiqiang Su (Huada: Beijing University of Chemical Technology)H-Index: 30
view all 7 authors...
We report here a facile synthesis of different zinc oxide (ZnO) nanostructures on reduced graphene oxide (RGO) by an in situ hydrothermal reaction. ZnO nanostructures with different morphologies on the surface of RGO were successfully synthesized by adjusting the mass ratio of Zn2+ to RGO in this reaction system. It was found that ZnO nanostructures with nanoparticles, mixed nanoparticles and microspindles, and microspindles were formed on RGO by adjusting the mass ratio of Zn2+ to RGO. The synt...
65 CitationsSource
#1Qing Li (Huada: Beijing University of Chemical Technology)H-Index: 10
#2Xiaoyuan Zhang (Huada: Beijing University of Chemical Technology)H-Index: 7
Last.Zhiqiang Su (Huada: Beijing University of Chemical Technology)H-Index: 30
view all 7 authors...
We report here the synthesis and characterization of a reactive liquid crystal (RLC) as a novel polymeric nucleating agent for the promotion of the nucleation efficiency of isotactic polypropylene (iPP). The RLC was synthesized by an in-situ photo-polymerization and was then grafted onto the molecular chain of iPP by the reactive blending. The phase transition and crystalline morphologies of RLC-iPP in the β-nucleation were studied. It is found that the nucleation efficiency of β-crystals of iPP...
6 CitationsSource
#1Gang Wei (University of Bremen)H-Index: 38
#2Qing Li (University of Bremen)H-Index: 10
Last.Lucio Colombi Ciacchi (University of Bremen)H-Index: 22
view all 4 authors...
We report here a systematic investigation of the interactions between two heteropolymer DNA single-strands (ssDNA) and graphite surfaces using AFM-based single-molecule force spectroscopy (SMFS). For this purpose, force-displacement (FD) curves are recorded by peeling single-molecule ssDNA from graphite. We find that the unbinding forces are affected both by the DNA sequences and the ionic strength of the liquid environment. In particular, the unbinding force decreases with the increase of ionic...
14 CitationsSource
12