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Mohamed A. El-Mokhtar
Assiut University
15Publications
4H-index
56Citations
Publications 21
Newest
Abstract Hepatitis E virus (HEV) infection is endemic in many developing countries and becomes of interest in the developed countries. Several animals are sources of HEV infection to humans. Recently, HEV was detected in the milk of cows in China, this data comes up with the probability of HEV transmission to humans via ingestion of contaminated milk. In Egypt, contaminated water and residing in rural communities are risk factors for HEV infection, while limited data is available on the zoonotic...
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The occurrence of tuberculosis (TB) and hepatitis C virus (HCV) infections in the same patient presents a unique clinical challenge. The impact of HCV infection on the immune response to TB remains poorly investigated in TB+/HCV+ patients. This study was conducted to evaluate the impact of HCV on the T-cell-mediated immune response to TB in coinfected patients. Sixty-four patients with active TB infections were screened for coinfection with HCV. The expression of immune activation markers IFN-γ,...
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#1Ibrahim M. Sayed (UCSD: University of California, San Diego)H-Index: 1
#2Amal A. Elkhawaga (Assiut University)
Last.Mohamed A. El-Mokhtar (Assiut University)H-Index: 4
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Abstract Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis globally. HEV belongs to the Hepeviridae family and at least five genotypes (gt) infect humans. Several animal species are reservoirs for different HEV strains, and they are the source of infection for humans. Some HEV strains are species specific, but other strains could cross species and infect many hosts. The study of HEV infection and pathogenesis was hampered due to the lack of an in vitro and in vivo robust ...
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#1Ayat A. Allam (Assiut University)H-Index: 6
#2Mohamed A. El-Mokhtar (Assiut University)H-Index: 4
Last.Mahmoud Elsabahy (Assiut University)H-Index: 23
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#1Ensaf M. Abdel-Maguid (Assiut University)
#2Sara M. Awad (Assiut University)H-Index: 4
Last.Marwa Ma Mekkawy (Assiut University)
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AbstractObjectives: To explore the impact of using topical stem cell-conditioned medium (SC-CM) after fractional carbon dioxide laser (FCL) vs. combined FCL and platelet-rich plasma (PRP) or FCL al...
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Endometriosis affects 5–10% of women in reproductive age and causes pelvic pain and subfertility. Exact etiology of the disease is unknown. Here, we present a microfluidic platform for characterizing mechanical properties of eutopic endometrial stromal cells of endometriosis patients based on cellular deformability inside narrow microchannels. Primary human endometrial stromal cells were isolated from eutopic endometrium of endometriosis patients (4407 cells, from 7 endometriosis patients) and f...
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#1Adel A. Gomaa (Assiut University)H-Index: 10
#2Rania Makboul (Assiut University)H-Index: 4
Last.Mariam A. Nicola (Assiut University)H-Index: 1
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Abstract Purpose Recent studies suggested that the non-familiar form of Alzheimer's disease (AD) could be consequence of metabolic syndrome and neuroinflammation. Elettaria cardamomum extract (EC) has exhibited antidiabetic, antioxidant and anti-inflammatory properties. This research was conducted to evaluate the effects of EC on AD-like alterations in rats induced by high fructose and high fat diet coupled with a single small dose of STZ (25 mg/kg) (T2DM rats). Methods Phytochemical analysis wa...
1 CitationsSource
1 Citations
#1Mostafa NasrH-Index: 1
#2Mohamed Farghaly (Assiut University)H-Index: 1
Last.Noha A. MousaH-Index: 9
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Abstract Female sex steroid hormones have a fundamental role in breast cancer. Meanwhile, current evidence supports the contribution of breast cancer stem cells in carcinogenesis, metastasis, and resistance to cytotoxic chemotherapy. Nevertheless, the interaction between breast cancer stem cells with sex hormones or key hormonal antagonists remains elusive. Objective To investigate the effect of diverse sex hormonal stimulation and suppression regimens on the proliferation of a primary human bre...
1 CitationsSource
#1Sherein G. Elgendy (Assiut University)H-Index: 1
#2Muhammad R. Abdel Hameed (Assiut University)H-Index: 1
Last.Mohamed A. El-Mokhtar (Assiut University)H-Index: 4
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Febrile neutropenic patients are at a high risk of life-threatening bacterial infections. Tigecycline was developed to treat multidrug-resistant isolates, however resistance to tigecycline in Klebsiella pneumoniae has been reported. Here, we investigated tigecycline resistance among K. pneumoniae isolated from febrile neutropenic patients admitted to Hematology ICU, Egypt. Out of 75 enrolled febrile neutropenic patients, 48 cases showed bacteriologically confirmed infection. The majority of case...
1 CitationsSource
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