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Jelena Filipović-Grčić
University of Zagreb
100Publications
24H-index
1,710Citations
Publications 103
Newest
#1Marieta Duvnjak Romić (Pliva (Croatia))H-Index: 3
#2Anja Sušac (University of Zagreb)
Last.Anita Hafner (University of Zagreb)H-Index: 12
view all 6 authors...
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Abstract Inflammation plays a key role in dry eye disease (DED) affecting millions of people worldwide. Non-steroidal anti-inflammatory drugs (NSAIDs) can be used topically to act on the inflammatory component of DED, but their limited aqueous solubility raises formulation issues. The aim of this study was development and optimization of functional cationic nanoemulsions (NEs) for DED treatment, as a formulation approach to circumvent solubility problems, prolong drug residence at the ocular sur...
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#1Bisera Jurišić Dukovski (University of Zagreb)H-Index: 2
#2Lea Mrak (University of Zagreb)H-Index: 1
Last.Anita Hafner (University of Zagreb)H-Index: 12
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AbstractIn this study, we present the development of an innovative dry powder dexamethasone (Dex) nasal delivery system comprising Dex-loaded lipid/alginate nanoparticles incorporated within pectin...
2 CitationsSource
#1Anita MartinacH-Index: 7
Last.Ivan JalšenjakH-Index: 19
view all 3 authors...
#1Marieta Duvnjak Romić (Pliva (Croatia))H-Index: 3
#2Drago Špoljarić (Pliva (Croatia))H-Index: 1
Last.Anita Hafner (University of Zagreb)H-Index: 12
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Abstract The aim of this study was to develop nanostructured lipid carrier (NLC)-loaded chitosan-based microspheres as innovative dry powder wound dressing, with melatonin incorporated in both, NLC and chitosan matrix of the proposed hybrid system. Melatonin-loaded NLCs were prepared by a hot homogenization technique, while NLC-loaded microspheres were produced by a spray-drying method. To optimize the critical formulation and process parameters for both NLC and hybrid system, a definitive scree...
1 CitationsSource
#1Željka Vanić (University of Zagreb)H-Index: 9
#2Zora Rukavina (University of Zagreb)H-Index: 2
Last.Nataša Škalko-BasnetH-Index: 25
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#1Ivona Tomić (University of Mostar)
#2Marina Juretić (Pliva (Croatia))H-Index: 2
Last.Jelena Filipović-Grčić (University of Zagreb)H-Index: 24
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Abstract Azelaic acid (AZA) is a dicarboxylic acid that is topically used in the treatment of acne and rosacea since it possesses antibacterial and keratolytic activity. The primary objective of this study was to develop an AZA nanocrystal suspension. It is expected that improved solubility and dissolution rate will result in advanced biopharmaceutical properties, primarily the dermal bioavailability. Furthermore, a topical nanocrystal AZA-loaded hydrogels composed of Pluronic® F127 and hyaluron...
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#1Lucija Vuletić (University of Zagreb)
#2Marina Herceg (Pliva (Croatia))
Last.Jelena Filipović-Grčić (University of Zagreb)H-Index: 24
view all 8 authors...
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#1Zora Rukavina (University of Zagreb)H-Index: 2
#2Maja Šegvić Klarić (University of Zagreb)H-Index: 15
Last.Željka Vanić (University of Zagreb)H-Index: 9
view all 5 authors...
Abstract Antibiotic delivery via liposomal encapsulation represents a promising approach for the efficient topical treatment of skin infections. The present study aimed to investigate the potential of using different types of azithromycin (AZT)-loaded liposomes to locally treat skin infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains. Conventional liposomes (CLs), deformable liposomes (DLs), propylene glycol-containing liposomes (PGLs) and cationic liposomes (CATLs) e...
2 CitationsSource
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