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Judith M. Martin
University of Pittsburgh
VirologyIntensive care medicineImmunologyMedicineBiology
70Publications
19H-index
2,053Citations
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Publications 77
Newest
#1Krissy K. Moehling (University of Pittsburgh)H-Index: 11
#2Richard K. Zimmerman (University of Pittsburgh)H-Index: 35
Last. Brendan Flannery (CDC: Centers for Disease Control and Prevention)H-Index: 34
view all 11 authors...
Abstract Background Current influenza vaccine effectiveness (VE) improvement efforts focus on minimizing egg adaptation mutations during manufacture. This study compared immune response of two FDA-approved quadrivalent inactivated influenza vaccines in an unblinded randomized controlled trial. Methods Participants were 144 community dwelling, healthy children/adolescents aged 4–20 years, randomized 1:1 in blocks of 4 to a vaccine grown in cell culture (ccIIV4 [Flucelvax®]; n = 85); or in egg med...
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#1Nader Shaikh (University of Pittsburgh)H-Index: 24
#2Timothy R. Shope (University of Pittsburgh)H-Index: 11
Last. Howard E. Rockette (University of Pittsburgh)H-Index: 53
view all 20 authors...
BACKGROUND To evaluate the efficacy of adjuvant systemic corticosteroids in reducing kidney scarring. A previous study suggested that use of adjuvant systemic corticosteroids reduces kidney scarring in children radiologically confirmed to have extensive pyelonephritis. Efficacy of corticosteroids for children with febrile urinary tract infection (UTI) has not been studied. METHODS Children aged 2 months to 6 years with their first febrile UTI were randomized to corticosteroids or placebo for 3 d...
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#1John F. Alcorn (University of Pittsburgh)H-Index: 30
#2Raghunandan Avula (University of Pittsburgh)H-Index: 1
Last. Jennifer P. Nagg (University of Pittsburgh)H-Index: 1
view all 14 authors...
The human immune response to inactivated influenza vaccine is dynamic and impacted by age and preexisting immunity. Our goal was to identify postvaccination transcriptomic changes in peripheral blo...
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#1Anne-Marie RickH-Index: 2
#1Anne-Marie Rick (University of Pittsburgh)
Last. Judith M. MartinH-Index: 19
view all 3 authors...
BACKGROUND: Among children with pharyngitis who test positive for group A Streptococcus (GAS), 10%-25% are GAS carriers. Current laboratory methods cannot distinguish acute infection from colonization. METHODS: We examined 2 separate longitudinal studies of children with symptomatic pharyngitis associated with a positive GAS throat culture (illness culture). In cohort 1, children presented with pharyngitis symptoms to a clinician, then had follow-up cultures at regular intervals. In cohort 2, th...
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#1Nader Shaikh (University of Pittsburgh)H-Index: 24
#2Judith M. Martin (University of Pittsburgh)H-Index: 19
Last. Timothy R. Shope (University of Pittsburgh)H-Index: 11
view all 16 authors...
Background The specificity of the leukocyte esterase test (87%) is suboptimal. The objective of this study was to identify more specific screening tests that could reduce the number of children who unnecessarily receive antimicrobials to treat a presumed urinary tract infection (UTI).
1 CitationsSource
#1Joseph A Lewnard (University of California, Berkeley)H-Index: 11
#2Lilith K. Whittles (Imperial College London)H-Index: 4
Last. Judith M. Martin (University of Pittsburgh)H-Index: 19
view all 4 authors...
BACKGROUND: Pharyngitis due to group A Streptococcus (GAS) represents a major cause of outpatient visits and antibiotic use in the United States. A leading vaccine candidate targets 30 of the >200 emm types of GAS. We aimed to assess natural protection conferred by GAS against respiratory symptoms. METHODS: In a 5-year study among school-aged children in Pittsburgh, Pennsylvania, pharyngeal cultures were obtained from children at 2-week intervals, and active surveillance was conducted for respir...
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BACKGROUND: Influenza vaccine is the most effective means to prevent influenza for the high-risk population of child care attendees. This national survey assessed child care center directors' reports of seasonal influenza vaccine requirements for children and adult caregivers. METHODS: This was a 2016 telephone-based survey of child care center directors randomly selected from a national database of licensed United States child care centers and queried about influenza vaccine requirements. Conce...
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#1Santiago M. C. Lopez (University of Pittsburgh)H-Index: 1
#2Judith M. Martin (University of Pittsburgh)H-Index: 19
Last. Nader Shaikh (University of Pittsburgh)H-Index: 24
view all 9 authors...
To develop a method to perform multiple tests on single nasopharyngeal (NP) swab. We collected a NP swab on children aged 2–12 years with acute sinusitis and processed it for bacterial culture, viruses, cytokine expression, and 16S ribosomal RNA gene sequencing analysis. During the course of the study, we expand the scope of evaluation to include RNA-sequencing, which we accomplished by cutting the tip of the swab. Of the 174 children enrolled, 126 (72.4%) had a positive bacterial culture and 12...
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#1Nader Shaikh (University of Pittsburgh)H-Index: 24
#2Judith M. Martin (University of Pittsburgh)H-Index: 19
Last. Timothy R. Shope (University of Pittsburgh)H-Index: 11
view all 20 authors...
Objective To determine whether treatment for urinary tract infections in children could be individualized using biomarkers for acute pyelonephritis. Study design We enrolled 61 children with febrile urinary tract infections, collected blood and urine samples, and performed a renal scan within 2 weeks of diagnosis to identify those with pyelonephritis. Renal scans were interpreted centrally by 2 experts. We measured inflammatory proteins in blood and urine using LUMINEX or an enzyme-linked immuno...
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#1Anne-Marie Rick (Boston Children's Hospital)
#2Haniah Zaheer (University of Pittsburgh)
Last. Judith M. Martin (Boston Children's Hospital)H-Index: 19
view all 3 authors...
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