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Hossam M. Abdallah
Cairo University
68Publications
14H-index
597Citations
Publications 74
Newest
#1Essam Abdel-SattarH-Index: 19
#2Hossam M. AbdallahH-Index: 14
Last.Haruki YamadaH-Index: 46
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#1Ahmad O. NoorH-Index: 3
#2Diena M. AlmasriH-Index: 2
Last.Sabrin R.M. IbrahimH-Index: 20
view all 7 authors...
Recently, the metabolites separated from endophytes have attracted significant attention, as many of them have a unique structure and appealing pharmacological and biological potentials. Isocoumarins represent one of the most interesting classes of metabolites, which are coumarins isomers with a reversed lactone moiety. They are produced by plants, microbes, marine organisms, bacteria, insects, liverworts, and fungi and possessed a wide array of bioactivities. This review gives an overview of is...
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#1Hossam M. Abdallah (Cairo University)H-Index: 14
#2Noura Ahmed Hassan (Zagazig University)H-Index: 4
Last.Hany M. El-Bassossy (Zagazig University)H-Index: 17
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Abstract Vasodilators are important pharmacologic agents for managing and/or treating hypertension. Medicinal plants are considered as valuable source of bioactive compounds. We used a bioguided approach to isolate, identify, and investigate the possible vasodilation activities and mechanism(s) of the prepared methanol extract from aerial parts of Psiadia punctulata (MAPP), its bioactive fraction and active compounds. Vascular effects of MAPP were studied using isolated artery technique in the p...
Source
#1Amjad A. Elghamdi (KAU: King Abdulaziz University)
#2Hossam M. Abdallah (Cairo University)H-Index: 14
Last.Sabrin R.M. Ibrahim (Taibah University)H-Index: 20
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#1Hossam M. AbdallahH-Index: 14
#2Esraa M. ZakariaH-Index: 2
Last.Hany M. El-BassossyH-Index: 17
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Exaggerated vasoconstriction plays important roles in vascular complication in aging and many diseases like diabetes. Here, we investigated the protective effect of Psiadia punctulata (PP) on advanced glycation end products (AGEs)-induced aggravated vasoconstriction. The effect of total methanol extract of PP leaves (PPT) on AGE-induced vascular injury was studied through bioassay-guided fractionation procedures in order to find the bioactive fraction and isolate the bioactive compounds. Vascula...
2 CitationsSource
#1Hossam M. Abdallah (Cairo University)H-Index: 14
#2Ali M. El-Halawany (Cairo University)H-Index: 14
Last.Hany M. El-Bassossy (KAU: King Abdulaziz University)H-Index: 17
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Exaggerated vasoconstriction plays a critical role in the development of hypertension in metabolic syndrome (MetS). A crude methanolic extract of Euryops arabicus (EA) was found to alleviate MetS-associated exaggerated vasoconstriction. The methanolic extract of EA had a direct vasodilatory effect which might account for the alleviation of vasoconstriction. Bio-guided fractionation revealed that the chloroform fraction is responsible for this effect. The observed vasodilation was not affected by...
Source
#1Mohamed F.S. Banjar (KAU: King Abdulaziz University)
#2Gamal A. Mohamed (Al-Azhar University)H-Index: 20
Last.Sabrin R.M. Ibrahim (Taibah University)H-Index: 20
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Abstract Two new cycloartane-type triterpenoids, cycloschimperols A [cycloart-20,24-dien-3β-ol] (3) and B [26,27-dinor-3β-hydroxy cycloartan-25-al] (4) and two known compounds, 24-methylenecycloartane (1) and cycloart-25-en-3-one (2) were separated from the aerial parts of Euphorbia schimperi C. Presl (Euphorbiaceae). The structural characterization of these metabolites was achieved by various spectroscopic analyses, including 1D and 2D NMR and HRESIMS as well as comparison with the published da...
Source
#1Ali M. El-Halawany (Cairo University)H-Index: 14
#2Samir M. OsmanH-Index: 2
Last.Hossam M. Abdallah (Cairo University)H-Index: 14
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AbstractChemical investigation of Vicia monantha subsp. monantha Retz. revealed isolation of one new hydroxy- fatty acid (6) identified as (6-Z, 10-E)-9-hydroxy henicosa-6,10-dienoic acid in addition to six known metabolites; hexadecanoic acid (1), β-sitosterol (2), β-amyrin (3), β-sitosterol-glucoside (4), 2,3-dihydroxypropyl tetradecanoate (5) and (Z)-9-hydroxypentadec-6-enoic acid (7). The cytotoxic effect of the isolated compounds was assessed by MTT assay using lung cancer A-549, prostate c...
Source
#1Taghreed A. Zamzami (KAU: King Abdulaziz University)H-Index: 1
#2Hossam M. Abdallah (Cairo University)H-Index: 14
Last.Sabrin R.M. Ibrahim (Taibah University)H-Index: 20
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Abstract Two new rare sesquiterpene glycosides, macrochaetosides A (3) and B (4), together with two known metabolites: stigmasterol (1) and cyclostenol (2) were separated from the CHCl3 fraction of the aerial parts of Echinops macrochaetus Boiss. (Asteraceae). Their chemical structures were established based on various spectroscopic methods in addition to mass spectrometry and comparison with literature data. Moreover, the cytotoxic activity of these metabolites was assessed towards breast adeno...
1 CitationsSource
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