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Aditya K. Sharma
Academy of Scientific and Innovative Research
4Publications
2H-index
25Citations
Publications 4
Newest
#1Aditya K. Sharma (AcSIR: Academy of Scientific and Innovative Research)H-Index: 2
#2Neha Dhasmana (AcSIR: Academy of Scientific and Innovative Research)H-Index: 4
Last.Yogendra Singh (DU: University of Delhi)H-Index: 31
view all 7 authors...
Virulence is described as an ability of an organism to infect the host and cause a disease. Virulence factors are the molecules that assist the bacterium colonize the host at the cellular level. These factors are either secretory, membrane associated or cytosolic in nature. The cytosolic factors facilitate the bacterium to undergo quick adaptive—metabolic, physiological and morphological shifts. The membrane associated virulence factors aid the bacterium in adhesion and evasion of the host cell....
11 CitationsSource
#1Aditya K. Sharma (Institute of Genomics and Integrative Biology)H-Index: 2
#2Divya AroraH-Index: 4
Last.Vinay Kumar NandicooriH-Index: 19
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Protein phosphatases play vital roles in phosphorylation-mediated cellular signaling. Although there are 11 serine/threonine protein kinases in Mycobacterium tuberculosis, only one serine/threonine phosphatase, PstP, has been identified. Although PstP has been biochemically characterized and multiple in vitro substrates have been identified, its physiological role has not yet been elucidated. In this study, we have investigated the impact of PstP on cell growth and survival of the pathogen in th...
14 CitationsSource
#1Lalit SinghH-Index: 6
#2Neha Dhasmana (Institute of Genomics and Integrative Biology)H-Index: 4
Last.Yogendra Singh (Institute of Genomics and Integrative Biology)H-Index: 9
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Polyhydroxyalkonoates (PHAs) are biological in origin, organic polyesters comprising the industrial and biomedical interest. This chapter summarizes the current advances, applications, limitations, and challenges of biopolymers in medicine. Biopolymers not only substitute the existing polymers, but novel combinations of diverse PHAs broaden the applicability and utility. The PHA-based implants are new dimensions of future in biomedical engineering.
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#1Neha Dubey (DU: University of Delhi)H-Index: 1
#2Raja Singh (JNU: Jawaharlal Nehru University)H-Index: 3
Last.Yogendra Singh (Institute of Genomics and Integrative Biology)H-Index: 9
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Biofilms are bacteria’s way of behaving like a multi-cellular organism. Bacteria have been constantly evolving in the face of myriad natural challenges since the first life form appeared. Over the centuries, they have survived under extreme conditions by virtue of their ability to form biofilms. Biofilms have proved to be an immensely strong collaborative effort of bacteria, and this interaction is administered via their quorum-sensing mechanism. A biofilm plays a crucial role in survival, dispe...
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