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Malcolm J. Faddy
Queensland University of Technology
100Publications
27H-index
3,440Citations
Publications 100
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This article describes the R package BinaryEPPM and its use in determining maximum likelihood estimates of the parameters of extended Poisson process models for grouped binary data. These provide a Poisson process family of flexible models that can handle unlimited under-dispersion but limited over-dispersion in such data, with the binomial distribution being a special case. Within BinaryEPPM, models with the mean and variance related to covariates are constructed to match a generalized linear m...
#1Malcolm J. Faddy (QUT: Queensland University of Technology)H-Index: 27
#2Matthew D. GosdenH-Index: 1
Last.Roger G. Gosden (W&M: College of William & Mary)H-Index: 49
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Abstract Enormous unmet needs for infertility treatment exist because access to assisted reproductive technologies is demographically skewed. Since the first IVF baby in 1978, the number of people conceived by reproductive technology has grown much faster than expected, reaching several million today and rapidly approaching 0.1% of the total world population. As more patients build families, and their children in turn become parents, the number owing their existence to assisted reproductive tech...
#1Christoph A. Ramseier (University of Bern)H-Index: 22
#2Age AnerudH-Index: 18
Last.Niklaus P. Lang (University of Bern)H-Index: 98
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OBJECTIVES To assess long-term attachment and periodontitis-related tooth loss (PTL) in untreated periodontal disease over 40 years. MATERIAL AND METHODS Data originated from the natural history of periodontitis study in Sri Lankan tea labourers first examined in 1970. In 2010, 75 subjects (15.6%) of the original cohort were re-examined. RESULTS PTL over 40 years varied between 0 and 28 teeth (mean 13.1). Four subjects presented with no PTL, while 12 were edentulous. Logistic regression revealed...
#1Gregory J. Seymour (University of Otago)H-Index: 54
#2J. E. Palmer (UQ: University of Queensland)H-Index: 11
Last.Mary P. Cullinan (University of Otago)H-Index: 30
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Background and Objective: Triclosan/copolymer toothpaste is effective in controlling plaque and gingivitis and in slowing the progression of periodontitis. This study describes its influence on microbiological and clinical outcomes, over a 5-year period, in patients with established cardiovascular disease (CVD). Material and Methods: Four-hundred and thirty-eight patients were recruited from the Cardiovascular Unit at The Prince Charles Hospital, Brisbane, Australia, and randomized to triclosan ...
This article describes the R package CountsEPPM and its use in determining maximum likelihood estimates of the parameters of extended Poisson process models. These provide a Poisson process based family of flexible models that can handle both underdispersion and overdispersion in observed count data, with the negative binomial and Poisson distributions being special cases. Within CountsEPPM models with mean and variance related to covariates are constructed to match a generalized linear model fo...
#1Mary P. Cullinan (University of Otago)H-Index: 30
#2J. E. Palmer (UQ: University of Queensland)H-Index: 11
Last.Gregory J. Seymour (University of Otago)H-Index: 54
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Background: Triclosan toothpaste is effective in controlling plaque and gingivitis and slowing progression of periodontitis; however, its influence on inflammatory biomarkers of cardiovascular disease (CVD), as well as on kidney and liver function, is unknown.Methods: Patients recruited from the Cardiovascular Unit at Prince Charles Hospital, Brisbane, Australia, were randomized to triclosan (n = 193) or placebo (n = 190) groups and assessed for total cholesterol (TC), high density lipoprotein (...
#1M. Depmann (UU: Utrecht University)H-Index: 7
#2Malcolm J. Faddy (QUT: Queensland University of Technology)H-Index: 27
Last.Frank J.M. Broekmans (UU: Utrecht University)H-Index: 58
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Context: Menopause has been hypothesized to occur when the nongrowing follicle (NGF) number falls below a critical threshold. Age at natural menopause can be predicted using NGF numbers and this threshold. These predictions support the use of ovarian reserve tests, reflective of the ovarian follicle pool, in menopause forecasting. Objective: The objective of the study was to investigate the hypothesis that age-specific NGF numbers reflect age at natural menopause. Design and Setting: Histologica...
#1A. La Marca (University of Modena and Reggio Emilia)H-Index: 23
#2Giulia Dondi (University of Modena and Reggio Emilia)H-Index: 3
Last.Malcolm J. Faddy (QUT: Queensland University of Technology)H-Index: 27
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STUDY QUESTION Can the number of oocytes retrieved in IVF cycles be predictive of the age at menopause? SUMMARY ANSWER The number of retrieved oocytes can be used as an indirect assessment of the extent of ovarian reserve to provide information on the duration of the reproductive life span in women of different ages. WHAT IS KNOWN ALREADY Menopause is determined by the exhaustion of the ovarian follicular pool. Ovarian reserve is the main factor influencing ovarian response in IVF cycles. As a c...
#1Helen M. Faddy (Australian Red Cross Blood Service)H-Index: 14
#2Clive R. Seed (Australian Red Cross Blood Service)H-Index: 21
Last.Robert Harley (Australian Red Cross Blood Service)H-Index: 5
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Background and Objectives In Australia, the risk of transfusion-transmitted malaria is managed through the identification of ‘at-risk’ donors, antibody screening enzyme-linked immunoassay (EIA) and, if reactive, exclusion from fresh blood component manufacture. Donor management depends on the duration of exposure in malarious regions (>6 months: ‘Resident’, <6 months: ‘Visitor’) or a history of malaria diagnosis. We analysed antibody testing and demographic data to investigate antibody persisten...
#1M. DóllemanH-Index: 2
#2Malcolm J. Faddy (QUT: Queensland University of Technology)H-Index: 27
Last.F. J. M. BroekmansH-Index: 15
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Context: Anti-Mullerian hormone (AMH) concentration reflects ovarian aging and is argued to be a useful predictor of age at menopause (AMP). It is hypothesized that AMH falling below a critical threshold corresponds to follicle depletion, which results in menopause. With this threshold, theoretical predictions of AMP can be made. Comparisons of such predictions with observed AMP from population studies support the role for AMH as a forecaster of menopause. Objective: The objective of the study w...
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