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Jesper Hallas
University of Southern Denmark
Internal medicineMedical prescriptionPopulationDiabetes mellitusMedicine
488Publications
50H-index
10.6kCitations
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Publications 490
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#1Daniel R. Morales (Dund.: University of Dundee)H-Index: 18
#2S. V. Morant (Dund.: University of Dundee)H-Index: 10
Last. Isla S. Mackenzie (Dund.: University of Dundee)H-Index: 25
view all 18 authors...
OBJECTIVE Due to cardiovascular safety concerns, the European Medicines Agency (EMA) recommended new contraindications and changes to product information for diclofenac across Europe in 2013. This study aims to measure its impact among targeted populations. METHOD Quarterly interrupted time series regression (ITS) analyses of diclofenac initiation among cohorts with contraindications (congestive cardiac failure CHF, ischaemic heart disease IHD, peripheral arterial disease PAD, cerebrovascular di...
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#1Maja Hellfritzsch (University of Southern Denmark)H-Index: 9
#2Shirley V. Wang (Brigham and Women's Hospital)H-Index: 17
Last. Anton Pottegård (University of Southern Denmark)H-Index: 25
view all 6 authors...
Using nationwide Danish registries, we conducted a population-based case-crossover study evaluating the association between switching from a vitamin K antagonist (VKA) to a direct oral anticoagulant (DOAC), and vice-versa, and 30-day risks of bleeding and arterial thromboembolism in atrial fibrillation (AF) patients. The case-crossover population was identified among oral anticoagulant users during 2011-2018 (n = 123,217), as AF patients with (a) a case-defining outcome and (b) an anticoagulant ...
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#1Lars Christian Lund (University of Southern Denmark)H-Index: 2
#2Mette Reilev (University of Southern Denmark)H-Index: 4
Last. Marianne Voldstedlund (SSI: Statens Serum Institut)H-Index: 7
view all 14 authors...
Importance During the ongoing coronavirus disease 2019 pandemic, case reports have suggested that the use of nonsteroidal anti-inflammatory drugs (NSAIDs) may lead to adverse outcomes. Objective To study the association of NSAID use with adverse outcomes in patients hospitalized with influenza or influenza pneumonia. Design, Setting, and Participants This cohort study used propensity score matching among 7747 individuals aged 40 years or older who were hospitalized with influenza, confirmed by p...
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#1Ina Qvist (AU: Aarhus University)H-Index: 3
#2Jes S. Lindholt (OUH: Odense University Hospital)H-Index: 47
Last. Lars Frost (AU: Aarhus University)H-Index: 29
view all 6 authors...
A total of 1,446 participants; 65-74-year-old men diagnosed with abdominal aortic aneurysm (AAA), peripheral arterial disease (PAD) or high blood pressure (HB) in the Viborg Vascular (VIVA) screening trial, were consecutively included and randomised to a telephone counselling (TC) or no TC 3 months after being screened positive. Data from VIVA were linked to data from Danish registers from 2007 to 2016. The primary outcome was a composite outcome of proportion of days covered (PDC) by statin, an...
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#1Katsiaryna Bykov (Brigham and Women's Hospital)H-Index: 13
#2Shirley V. Wang (Brigham and Women's Hospital)H-Index: 17
Last. Joshua J. Gagne (Brigham and Women's Hospital)H-Index: 31
view all 6 authors...
PURPOSE The case-crossover design is increasingly used to evaluate the effects of chronic medications; however, as traditionally implemented in pharmacoepidemiology, with referent period preceding the outcome, it may lead to bias in the presence of persistent exposures. We aimed to evaluate the extent and magnitude of bias in case-crossover analyses of chronic and persistent exposures, using simulations. METHODS We simulated cohorts with either 30-day, 180-day, or 2-year exposure duration; and w...
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#1Lars Christian Lund (University of Southern Denmark)H-Index: 2
#2Kasper Bruun Kristensen (University of Southern Denmark)H-Index: 2
Last. Jesper Hallas (University of Southern Denmark)H-Index: 50
view all 11 authors...
Background Concerns over the safety of non-steroidal anti-inflammatory drug (NSAID) use during SARS-CoV-2 infection have been raised. Objectives To study whether use of NSAIDs is associated with adverse outcomes and mortality during SARS-CoV-2 infection. Design Population based cohort study Setting Danish administrative and health registries. Participants Individuals tested positive for SARS-CoV-2 during Feb 27, 2020 to Apr 29, 2020. Treated individuals (defined as a filled NSAID prescription up...
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#1Mette Reilev (University of Southern Denmark)H-Index: 4
#2Kasper Bruun Kristensen (University of Southern Denmark)H-Index: 2
Last. Nikolai Constantin Brun (Danish Medicines Agency)H-Index: 2
view all 18 authors...
Objective To provide population-level knowledge on individuals at high risk of severe and fatal coronavirus disease 2019 (COVID-19) in order to inform targeted protection strategies in the general population and appropriate triage of hospital contacts. Design, Setting, and Participants Nationwide population-based cohort of all 228.677 consecutive Danish individuals tested (positive or negative) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA from the identification of the fi...
1 CitationsSource
#1Katrine Bødkergaard (AU: Aarhus University)
#2Randi Selmer (FHI: Norwegian Institute of Public Health)H-Index: 46
Last. Henrik Støvring (AU: Aarhus University)H-Index: 28
view all 7 authors...
PURPOSE: A pervasive problem in registry-based pharmacoepidemiological studies is what exposure duration to assign to individual prescriptions. The parametric waiting time distribution (WTD) has been proposed as a method to estimate such durations. However, when prescription durations vary due to seasonal stockpiling, WTD estimates will vary with choice of index date. To counter this, we propose using random index dates. METHODS: Within a calendar period of a given length, δ, we randomly sample ...
Source
#1Jes S. Lindholt (OUH: Odense University Hospital)H-Index: 47
#2Jan Frystyk (OUH: Odense University Hospital)
Last. Axel Cosmus Pyndt Diederichsen (CIMA: Chartered Institute of Management Accountants)H-Index: 22
view all 5 authors...
Purpose: Cardiovascular mortality remains high among patients with diabetes compared with the general population. The primary aim was to evaluate the interest in and demand for advanced cardiovascular screening in patients with diabetes; the secondary aim was to explore its efficiency in detecting unprotected subclinical cardiovascular disease (CVD). Patients and Methods: In a cross-sectional design, randomly selected 40-60-year-old men and women with diabetes were invited to the screening trial...
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#1Pernille Stegemejer Sønderskov (OUH: Odense University Hospital)H-Index: 1
#2Jes Sandal Lindholt (OUH: Odense University Hospital)H-Index: 1
Last. Grazina UrbonavicieneH-Index: 11
view all 14 authors...
AIMS : Vitamin K antagonists (VKAs) are suspected of causing aortic valve calcification (AVC). The objective of this study was to clarify whether patients undergoing VKA treatment have increased AVC scores compared to patients treated with new oral anticoagulants (NOACs) and patients who never have been treated with VKA/NOAC. METHODS AND RESULTS : We included participants from the population-based DANCAVAS trial (n = 15 048). Information on confounders was collected, and the AVC scores were meas...
1 CitationsSource
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