Match!
Vinod Nair
All India Institute of Medical Sciences
16Publications
9H-index
231Citations
Publications 16
Newest
#1Neha Negi (AIIMS: All India Institute of Medical Sciences)H-Index: 1
#2Kallol Kumar Roy (AIIMS: All India Institute of Medical Sciences)H-Index: 17
Last.Perumal Vanamail (AIIMS: All India Institute of Medical Sciences)H-Index: 7
view all 5 authors...
Background: Laparoscopy is important for management of endometriosis patients with estimation of endometriosis fertility index (EFI) which can predict reproductive outcome. Aims: This study aims to evaluate clinical outcome in laparoscopically managed pelvic endometriosis and correlation of reproductive outcome with EFI. Setting and Design: Retrospective cohort study carried out in the Department of Obstetrics and Gynecology. Materials and Methods: Our study included 123 patients who had undergo...
Source
#1Rohit Kumar (AIIMS: All India Institute of Medical Sciences)H-Index: 6
#2Vinod Nair (AIIMS: All India Institute of Medical Sciences)H-Index: 9
Last.Surender Singh (AIIMS: All India Institute of Medical Sciences)H-Index: 22
view all 4 authors...
Aim The present study was carried out to evaluate the anti-inflammatory and antiarthritic activity of Rosa centifolia aqueous extract (RC) in a carrageenan-induced paw edema model and complete Freund's adjuvant (CFA)-induced arthritis. Methods Anti-inflammatory activity of RC was evaluated using the carrageenan-induced paw edema model in rats. Arthritis was induced in rats by sub-plantar administration of CFA. Joint size was measured at regular intervals by using a micrometer screw gauge. Serum ...
10 CitationsSource
#1Rohit Kumar (AIIMS: All India Institute of Medical Sciences)H-Index: 6
#2Vinod Nair (AIIMS: All India Institute of Medical Sciences)H-Index: 9
Last.S. ArunrajaH-Index: 3
view all 5 authors...
ABSTRACTThe present study was carried out to investigate the anti-arthritic activity of Berberis aristata hydroalcoholic extract (BAHE) in formaldehyde-induced arthritis and adjuvant-induced arthritis (AIA) model. Arthritis was induced by administration of either formaldehyde (2% v/v) or CFA into the subplantar surface of the hind paw of the animal. In formaldehyde-induced arthritis and AIA, treatment of BAHE at doses 50, 100 and 200 mg/kg orally significantly decreased joint inflammation as evi...
3 CitationsSource
Introduction:Rosa centifolia L. (Rosaceae) have been used for the treatment of joint pain and rheumatoid arthritis (RA) in the traditional system of medicine. Aim: In this study, the antiarthritic activity of the alcoholic extract from the floral parts of R. centifolia was investigated. Materials and Methods: The anti-inflammatory and antiarthritic activity of R. centifolia alcoholic extract (RCAE: 32, 64, and 128 mg/kg) was evaluated using the carrageenan-induced paw edema and complete Freund's...
6 CitationsSource
#1Syed Ovais (Hamdard University)H-Index: 9
#2Shafiya Yaseen (Hamdard University)H-Index: 7
Last.Kalim Javed (Hamdard University)H-Index: 17
view all 8 authors...
Nine novel 4-[3-(4-Dimethylamino-phenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl]-benzenesulfonamides (2a-i) were synthesized and evaluated for their anti-inflammatory and antiproliferative activities. These compounds (2a-i) showed moderate to strong anti-inflammatory activity in carrageenan rat paw oedema test. Compounds 2b, 2d and 2g showing comparable anti-inflammatory activity to that of reference drug celecoxib were evaluated for their ulcerogenic and analgesic activities. The effect of 2b, 2d and ...
10 CitationsSource
#1Shafiya Yaseen (Hamdard University)H-Index: 7
#2Syed Ovais (Hamdard University)H-Index: 9
Last.Kalim Javed (Hamdard University)H-Index: 17
view all 8 authors...
Nine 4-arylphthalazones bearing benzenesulfonamide (2a–i) were synthesized by the condensation of the appropriate 2-aroylbenzoic acid (1a–i) and 4-hydrazinobenzenesulfonamide in ethanol. The structures of these compounds were elucidated by elemental analysis, IR, 1H NMR, 13C NMR, and MS spectroscopy. Two compounds, 2b and 2i, showed significant anti-inflammatory activity comparable to that of the standard drug celecoxib in the carrageenan-induced rat paw edema model. These compounds (2b and 2i) ...
4 CitationsSource
#1Rafia BashirH-Index: 7
#2Kalim JavedH-Index: 17
Last.Vinod NairH-Index: 9
view all 10 authors...
Some unnatural chalcones (1a-q) and flavones (2a-d) have been synthesized and evaluated for their antiinflammatory activity using carrageenan-induced rat paw edema assay. The flavone 2c (6-Chloro-7-methyl-3', 4'- dimethoxyflavone) had higher anti-inflammatory activity and superior gastrointestinal safety profiles than the reference drug celecoxib. Compound 2c showed almost two times better selective inhibitory activity towards COX-2 enzyme than celecoxib. 2'-Hydroxychalcones (1a-h) showed modera...
Source
#1Vinod Nair (AIIMS: All India Institute of Medical Sciences)H-Index: 9
#2Surender Singh (AIIMS: All India Institute of Medical Sciences)H-Index: 22
Last.Yogendra Kumar Gupta (AIIMS: All India Institute of Medical Sciences)H-Index: 36
view all 3 authors...
Background: Coriandrum sativum has been used in the traditional systems of medicine for management of arthritis and other inflammatory disorders. Objectives: In this study, we have evaluated the anti-inflammatory and anti-granuloma activities of Coriandrum sativum hydroalcoholic extract (CSHE) in experimental models. Materials and Methods: The anti-inflammatory activity of CSHE was evaluated using carrageenan-induced paw edema model and the anti-granuloma activity of CSHE was evaluated using the...
5 CitationsSource
#1Vinod NairH-Index: 9
#2Rohit KumarH-Index: 6
Last.Yogendra Kumar GuptaH-Index: 36
view all 4 authors...
2 CitationsSource
#1Vinod Nair (AIIMS: All India Institute of Medical Sciences)H-Index: 9
#2Rohit Kumar (AIIMS: All India Institute of Medical Sciences)H-Index: 6
Last.Yogendra Kumar Gupta (AIIMS: All India Institute of Medical Sciences)H-Index: 36
view all 4 authors...
The present study evaluates the anti-inflammatory and antigranuloma activity of CLHE in experimental models, viz. carrageenan-induced paw edema, subcutaneous cotton pellet implantation-induced granuloma formation, and complete Freund's adjuvant-induced stimulation of peritoneal macrophages in rats. Serum TNF-alpha, IL-6, and IL-1 beta levels were estimated as markers for global effects of inflammation. TNF-R1 protein expression was estimated in stimulated peritoneal macrophages. There was a sign...
17 CitationsSource
12