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구승엽
283Publications
23H-index
1,881Citations
Publications 280
Newest
1 CitationsSource
Hormonal disturbances, such as hyperandrogenism, are considered important for developing polycystic ovary syndrome (PCOS) in humans. Accordingly, directly hormone-regulated animal models are widely used for studying PCOS, as they replicate several key PCOS features. However, the pathogenesis and treatment of PCOS are still unclear. In this review, we aimed to investigate animal PCOS models and PCOS-like phenotypes in animal experiments without direct hormonal interventions and determine the unde...
Source
#1Yoon Young Kim (SNU: Seoul National University)H-Index: 34
#2Yong Jin Kim (KU: Korea University)H-Index: 10
Last.Chang Suk Suh (SNU: Seoul National University)H-Index: 26
view all 6 authors...
Background: Vitamin is a well-known co-factor for many metabolic processes and its roles in fertility and follicular growth have been studied. Vitamin supplementation is frequently achieved by daily ingestion in the form of a complex capsule. However, the role of single and complex vitamins in in vitro maturation of murine follicles is not fully elucidated.
Source
#1Yoon Young Kim (SNU: Seoul National University)H-Index: 34
#2Bo Bin Choi (SNU: Seoul National University)H-Index: 1
Last.구승엽 (SNU: Seoul National University)H-Index: 23
view all 6 authors...
Background: Thin or damaged endometrium causes uterine factor-derived infertility resulting in a failure of embryonic implantation. Regeneration of endometrium is a major issue in gynecology and reproductive medicine. Various types of cells and scaffolds were studied to establish an effective therapeutic strategy. For this type of investigations, production of optimal animal models is indispensable. In this study, we tried to establish various murine uterine damage models and compared their feat...
2 CitationsSource
#1Yoon Young Kim (SNU: Seoul National University)H-Index: 34
#2Byeong Cheol KangH-Index: 14
Last.구승엽H-Index: 23
view all 8 authors...
The in vitro maturation of oocytes is frequently used as an assisted reproductive technique (ART), and has been successfully established in humans and rodents. To overcome the limitations of ART, novel procedures for the in vitro maturation of early follicles are emerging. During the follicle isolation procedure, the unintended rupture of each follicle leads to a release of extra oocytes. Such oocytes, which are obtained during follicle isolation from marmosets, can be used for early maturation ...
2 CitationsSource
#1Yoon Young KimH-Index: 34
#2Woo Oh KimH-Index: 1
Last.구승엽H-Index: 23
view all 6 authors...
1 CitationsSource
#1Sung Woo Kim (SNU: Seoul National University)H-Index: 1
#2Yong Jin Kim (KU: Korea University)H-Index: 10
Last.Young Min Choi (SNU: Seoul National University)H-Index: 30
view all 8 authors...
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#2Hoon-Sik KimH-Index: 26
Last.Chang Suk SuhH-Index: 26
view all 4 authors...
Source
#1Yong Jin Kim (KU: Korea University)H-Index: 10
#2Yoon Young Kim (SNU: Seoul National University)H-Index: 34
Last.Chang Suk SuhH-Index: 26
view all 6 authors...
The expression profile of microRNA (miRNA) in uterine leiomyoma (UL) cells is different from that in normal uterine myometrial (UM) cells. The effect of UL cells on uterine receptivity might vary according to their ability to distort the uterine endometrial cavity. However, the variation in miRNA expression profiles between endometrial cavity-distorting leiomyoma (ECDL) and endometrial cavity non-distorting leiomyoma (ECNDL) cells remains unknown. This study aimed to elucidate whether the expres...
4 CitationsSource
#1Seung Woo Han (Catholic University of Korea)H-Index: 1
#2Yoon Young Kim (SNU: Seoul National University)H-Index: 34
Last.Jun Won Yun (Catholic University of Korea)H-Index: 7
view all 7 authors...
BACKGROUND: Despite recent advance in conventional cancer therapies including surgery, radiotherapy, chemotherapy, and immunotherapy to reduce tumor size, unfortunately cancer mortality and metastatic cancer incidence remain high. Along with a deeper understanding of stem cell biology, cancer stem cell (CSC) is important in targeted cancer therapy. Herein, we review representative patents using not only normal stem cells as therapeutics themselves or delivery vehicles, but also CSCs as targets f...
2 CitationsSource
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