Jon L. Pryor
University of Minnesota
UrologyEndocrinologyPremature ejaculationMedicineBiology
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Publications 64
#1A. Nicholson (UMN: University of Minnesota)
#2Jon L. Pryor (UMN: University of Minnesota)H-Index: 25
Last. A. Makhlouf (UMN: University of Minnesota)
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#1Keith Jarvi (MSH: Mount Sinai Hospital, Toronto)H-Index: 2
#2Eugene DulaH-Index: 2
Last. Monica Seger (Bayer USA: Bayer Corporation)H-Index: 2
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Purpose: Phosphodiesterase type 5 inhibitors are the first choice therapy in the treatment of erectile dysfunction. Many men in their reproductive years are now using phosphodiesterase type 5 inhibitors. The purpose of this study was to determine the effects of 6 months of treatment with 20 mg vardenafil, compared with 100 mg sildenafil and placebo, on semen characteristics and reproductive hormones in men with and without erectile dysfunction.Materials and Methods: This was a randomized, double...
34 CitationsSource
#1Irwin GoldsteinH-Index: 77
#2Edward D. Kim (UT: University of Tennessee)H-Index: 24
Last. Sanjeev Ahuja (Eli Lilly and Company)H-Index: 10
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ABSTRACT Introduction Limited efficacy and safety data exist from open‐label clinical trials of phosphodiesterase 5 inhibitors in men with erectile dysfunction (ED) and multiple comorbid (MCM) conditions, historically a difficult group to treat. Aim A multicenter study (Multiple Observations in Men with Erectile Dysfunction in National Tadalafil Study in the US) assessed efficacy and safety of tadalafil in men with ED and MCM conditions. Main Outcome Measures The primary end point was change fro...
39 CitationsSource
#1Irwin GoldsteinH-Index: 77
#2Edward D. KimH-Index: 24
Last. Sanjeev AhujaH-Index: 10
view all 8 authors...
#1Jon L. Pryor (UMN: University of Minnesota)H-Index: 25
3 CitationsSource
#1Jon L. Pryor (UMN: University of Minnesota)H-Index: 25
#1Jon L. Pryor (UMN: University of Minnesota)H-Index: 25
#2Stanley E. AlthofH-Index: 47
Last. Sherron Kell (Alza)H-Index: 12
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Summary Background No drugs are approved for treatment of premature ejaculation. Our aim was to determine the efficacy and tolerability of on-demand dapoxetine in patients with severe premature ejaculation. Methods We determined the efficacy of dapoxetine in a prospectively predefined integrated analysis of two 12-week randomised, double-blind, placebo-controlled, phase III trials of identical design done independently, in parallel, at 121 sites in the USA. Men with moderate-to-severe premature ...
235 CitationsSource
#1Ann Lavers (UMN: University of Minnesota)H-Index: 4
#2David J. Swanlund (UMN: University of Minnesota)H-Index: 19
Last. Kenneth P. Roberts (UMN: University of Minnesota)H-Index: 29
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Persistent infertility after apparently successful vasectomy reversal is common. One possible etiology is epididymal epithelial dysfunction resulting in improper sperm maturation after vasectomy reversal. The epididymal epithelium secretes a number of proteins that are thought to be required for the maturation of sperm. Ligation of the vas deferens during vasectomy may affect the synthesis of some of these proteins. In the present study, the function of the epididymal epithelium was assessed at ...
13 CitationsSource
#1Wayne J.G. Hellstrom (Tulane University)H-Index: 63
#2Muammer Kendirci (Tulane University)H-Index: 27
Last. Jon L. Pryor (UMN: University of Minnesota)H-Index: 25
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Purpose: We investigated the efficacy and safety of intralesional interferon α-2b for the treatment of Peyronie’s disease.Materials and Methods: A total of 117 consecutive patients with a mean age of 55.1 years who had Peyronie’s disease were enrolled in a single-blind, multicenter, placebo controlled, parallel study to determine the efficacy and safety of intralesional interferon α-2b therapy (Schering, Kenilworth, New Jersey), including 62 who received placebo and 55 who received interferon α-...
137 CitationsSource
#1Mark Sigman (Brown University)H-Index: 23
#2Stacy L. Glass (UMN: University of Minnesota)H-Index: 2
Last. Jon L. Pryor (UMN: University of Minnesota)H-Index: 25
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Objective To determine the effect of oral carnitine supplementation on the semen parameters of men with idiopathic asthenospermia. Design Prospective, randomized, double-blind placebo-controlled study. Setting Academic tertiary referral centers. Patient(s) Male patients presenting with infertility and with sperm motility of 10%–50% were selected. Intervention(s) Patients were randomized to 24-week treatment arms of oral carnitine (2,000 mg L-carnitine and 1,000 mg L-acetyl-carnitine per day) or ...
80 CitationsSource