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S. Roux
Nelson Mandela Metropolitan University
17Publications
8H-index
331Citations
Publications 17
Newest
#1Ernst Fredericks (NMU: Nelson Mandela Metropolitan University)H-Index: 2
#2Gill Dealtry (NMU: Nelson Mandela Metropolitan University)H-Index: 6
Last.S. Roux (NMU: Nelson Mandela Metropolitan University)H-Index: 8
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Background. The wnt/APC/β-catenin pathway is a critical initiator in colorectal carcinogenesis in both hereditary and sporadic colorectal cancer (CRC). The progression of this process remains incompletely understood, although inflammation is pivotal. Drivers of inflammation are elevated in malignant tissue and have been shown to regulate β-catenin expression. Interleukin-17A (IL-17A) is protumorigenic at elevated levels via COX-2 stimulation. Elevated peroxisome proliferator-activated receptor γ...
#1Cheryl Stevenson (UCT: University of Cape Town)H-Index: 1
#2Renée Blaauw (UCT: University of Cape Town)H-Index: 10
Last.S. Roux (NMU: Nelson Mandela Metropolitan University)H-Index: 8
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Abstract Objectives Irritable bowel syndrome (IBS) is a common diagnosis in gastroenterology. Its etiology is unknown and therapeutic options limited. Trials suggest probiotics may be beneficial. The aim of this study was to assess the symptomatic efficacy of Lactobacillus plantarum 299 v ( L. plantarum 299 v) for the relief of abdominal pain in patients with IBS fulfilling Rome II criteria. Methods This study was conducted in a referral hospital. Trial participants were randomized to receive ei...
#1O. Ibraheem (University of Fort Hare)H-Index: 1
#2C.E.J. Botha (Rhodes University)H-Index: 7
Last.S. Roux (NMU: Nelson Mandela Metropolitan University)H-Index: 8
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The role of the sucrose transporter OsSUT1 in assimilate retrieval via the xylem, as a result of damage to and leakage from punctured phloem was examined after rusty plum aphid (Hysteroneura setariae, Thomas) infestation on leaves from 3-week-old rice (Oryza sativa L. cv Nipponbare) plants. Leaves were examined over a 1- to 10-day infestation time course, using a combination of gene expression and β-glucuronidase (GUS) reporter gene analyses. qPCR and Western blot analyses revealed differential ...
#1Cheryl Stevenson (Stellenbosch University)H-Index: 2
#2Renée Blaauw (Stellenbosch University)H-Index: 10
Last.S. Roux (NMU: Nelson Mandela Metropolitan University)H-Index: 8
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Objective: The objective was to assess the dietary intake of subjects with irritable bowel syndrome (IBS) and to compare it to that of international recommendations. The hypothesising assumption of this study was that a situation in which subjects insist that diet or trigger foods play a part in symptom generation may lead to an unbalanced dietary intake. Design: This was a descriptive observational study, with an analytical component. Setting: A private, secondary care-level clinic in South Afr...
#1S. Williams (NMU: Nelson Mandela Metropolitan University)H-Index: 1
#2S. Roux (NMU: Nelson Mandela Metropolitan University)H-Index: 8
Last.Gill Dealtry (NMU: Nelson Mandela Metropolitan University)H-Index: 6
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Abstract Ethnopharmacological relevance The African medicinal plant Sutherlandia frutescens (L.) R.Br. (Fabaceae) is traditionally used to treat diabetes and has been shown to have anti-diabetic properties in animal models. The present study investigated the capacity of an aqueous extract of Sutherlandia frutescens to prevent insulin resistance (a precursor of type 2 diabetes) in a human liver cell culture and to identify genes regulated by Sutherlandia frutescens treatment. Materials and method...
#1Janine MacKenzie (NMU: Nelson Mandela Metropolitan University)H-Index: 2
#2T Koekemoer (NMU: Nelson Mandela Metropolitan University)H-Index: 8
Last.Gill Dealtry (NMU: Nelson Mandela Metropolitan University)H-Index: 6
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High fat diet induced insulin resistance correlates with dyslipidaemia and ectopic fat deposits in skeletal muscle and liver. The effects of Sutherlandia frutescens, an antidiabetic medicinal plant, on lipid metabolism were evaluated in an insulin resistant (IR) rat model and in 3 T3-preadipocytes. Wistar rats received normal diet (ND) or high fat diet (HFD). After the onset of IR in the HFD group, the rats were subdivided into two subgroups, which either continued with HFD or were treated with ...
#1Omodele IbraheemH-Index: 3
#2Gill DealtryH-Index: 6
Last.Graeme Bradley (University of Fort Hare)H-Index: 17
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Rice, like other plants, contains a number of sucrose transporter genes. However knowledge of their expression and regulation during environmental stress conditions is limited. Using expressional analysis, the role of sucrose transporter genes was examined during drought and salinity stress conditions in 3-week-old rice (Orzya sativa L. cv Nipponbare) plants, over a time-course of 1 to 10 days of stress treatment. Among the 5 rice sucrose transporter genes identified, only OsSUT2 was up-regulate...
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