Daesik Kim
Seoul National University
82Publications
20H-index
2,437Citations
Publications 82
Newest
Published on Mar 1, 2019in Advanced Science 12.44
Jaeyoung Yoon2
Estimated H-index: 2
(Seoul National University),
Yunsik Joo3
Estimated H-index: 3
(Seoul National University)
+ 6 AuthorsYongtaek Hong24
Estimated H-index: 24
(Seoul National University)
Source Cite
Published on Feb 1, 2019in Smart Materials and Structures 2.96
Taehoon Kim33
Estimated H-index: 33
(Seoul National University),
Daesik Kim20
Estimated H-index: 20
(Seoul National University)
+ 3 AuthorsYongtaek Hong24
Estimated H-index: 24
(Seoul National University)
Conductive thin films are typically subject to crack formation and propagation under tensile strain, turning into insulating films due to complete breakage at large strain. However, if such crack propagation can be intentionally designed, repetitive resistance change can be obtained and used for implementation of high-performance strain sensors that are suitable for biocompatible and stretchable electronic applications. In this work, therefore, we introduce a fiber-reinforced region, which is fo...
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Published on Mar 4, 2019in Nature Biotechnology 35.72
Daesik Kim20
Estimated H-index: 20
(Seoul National University),
Da-eun Kim2
Estimated H-index: 2
(Seoul National University)
+ 2 AuthorsJinsoo Kim52
Estimated H-index: 52
(University of Science and Technology, Sana'a)
Adenine base editors1 enable efficient targeted adenine-to-guanine single nucleotide conversions to induce or correct point mutations in human cells, animals, and plants1–4. Here we present a modified version of Digenome-seq, an in vitro method for identifying CRISPR (clustered regularly interspaced short palindromic repeats)-induced double-strand breaks using whole-genome sequencing5–8, to assess genome-wide target specificity of adenine base editors. To produce double-strand breaks at sites co...
1 Citations Source Cite
Published on Jun 20, 2019in Annual Review of Biochemistry 20.15
Daesik Kim20
Estimated H-index: 20
,
Kevin Luk (University of Massachusetts Medical School)+ 1 AuthorsJinsoo Kim52
Estimated H-index: 52
Source Cite
Published on Mar 1, 2019in Advanced Science 12.44
Jaeyoung Yoon2
Estimated H-index: 2
(Seoul National University),
Yunsik Joo3
Estimated H-index: 3
(Seoul National University)
+ 6 AuthorsYongtaek Hong24
Estimated H-index: 24
(Seoul National University)
Source Cite
Published on Jun 1, 2018 in Computer Vision and Pattern Recognition
Daesik Kim20
Estimated H-index: 20
(Seoul National University),
Young Joon Yoo4
Estimated H-index: 4
(Seoul National University)
+ 2 AuthorsNojun Kwak16
Estimated H-index: 16
(Seoul National University)
In this work, we introduce a new algorithm for analyzing a diagram, which contains visual and textual information in an Abstract and integrated way. Whereas diagrams contain richer information compared with individual image-based or language-based data, proper solutions for automatically understanding them have not been proposed due to their innate characteristics of multi-modality and arbitrariness of layouts. To tackle this problem, we propose a unified diagram-parsing network for generating k...
1 Citations Source Cite
Published on Dec 1, 2018in Nature Communications 12.35
Jungjoon K. Lee2
Estimated H-index: 2
,
Euihwan Jeong4
Estimated H-index: 4
(Seoul National University)
+ 8 AuthorsSeokjoong Kim13
Estimated H-index: 13
The use of CRISPR-Cas9 as a therapeutic reagent is hampered by its off-target effects. Although rationally designed S. pyogenes Cas9 (SpCas9) variants that display higher specificities than the wild-type SpCas9 protein are available, these attenuated Cas9 variants are often poorly efficient in human cells. Here, we develop a directed evolution approach in E. coli to obtain Sniper-Cas9, which shows high specificities without killing on-target activities in human cells. Unlike other engineered Cas...
10 Citations Source Cite
Published on Dec 1, 2018in Nature Communications 12.35
Taeyoung Koo14
Estimated H-index: 14
(University of Science and Technology, Sana'a),
Sung Wook Park13
Estimated H-index: 13
(Seoul National University)
+ 6 AuthorsJin-Soo Kim51
Estimated H-index: 51
(University of Science and Technology, Sana'a)
LbCpf1, derived from Lachnospiraceae bacterium ND2006, is a CRISPR RNA-guided endonuclease and holds promise for therapeutic applications. Here we show that LbCpf1 can be used for therapeutic gene editing in a mouse model of age-related macular degeneration (AMD). The intravitreal delivery of LbCpf1, targeted to two angiogenesis-associated genes encoding vascular endothelial growth factor A (Vegfa) and hypoxia inducing factor 1a (Hif1a), using adeno-associated virus, led to efficient gene disrup...
4 Citations Source Cite
Published on Dec 1, 2018in Advanced Functional Materials 13.32
Eunho Oh4
Estimated H-index: 4
(Seoul National University),
Taehoon Kim33
Estimated H-index: 33
(Seoul National University)
+ 7 AuthorsYongtaek Hong24
Estimated H-index: 24
(Seoul National University)
Source Cite
Published on Jan 1, 2018in arXiv: Computation and Language
Daesik Kim20
Estimated H-index: 20
,
Seonhoon Kim1
Estimated H-index: 1
,
Nojun Kwak16
Estimated H-index: 16
In this work, we introduce a novel algorithm for solving the textbook question answering (TQA) task which describes more realistic QA problems compared to other recent tasks. We mainly focus on two related issues with analysis of TQA dataset. First, it requires to comprehend long lessons to extract knowledge. To tackle this issue of extracting knowledge features from long lessons, we establish knowledge graph from texts and incorporate graph convolutional network (GCN). Second, scientific terms ...
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