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Y.M. Lenighan
University College Dublin
13Publications
3H-index
26Citations
Publications 15
Newest
#1M. O'Reilly (UCD: University College Dublin)H-Index: 4
#2Y.M. Lenighan (UCD: University College Dublin)H-Index: 3
Last.Fiona C. McGillicuddy (UCD: University College Dublin)H-Index: 19
view all 11 authors...
Source
#1Y.M. LenighanH-Index: 3
#2Anne P. NugentH-Index: 18
Last.Breige A. McNultyH-Index: 11
view all 8 authors...
Source
#1Y.M. LenighanH-Index: 3
#2Breige A. McNultyH-Index: 11
Last.Helen M. RocheH-Index: 2
view all 3 authors...
Source
#1Y.M. LenighanH-Index: 3
#2M. O'ReillyH-Index: 4
Last.Helen M. RocheH-Index: 53
view all 10 authors...
Source
#1M. O'Reilly (UCD: University College Dublin)H-Index: 4
#2Sarina Kajani (UCD: University College Dublin)H-Index: 1
Last.Fiona C. McGillicuddy (UCD: University College Dublin)H-Index: 19
view all 6 authors...
Source
#1Maria HughesH-Index: 13
#2Y.M. Lenighan (UCD: University College Dublin)H-Index: 3
Last.Helen M. Roche (UCD: University College Dublin)H-Index: 53
view all 4 authors...
Finding genetic variants that cause functional disruption or regulatory change among the many implicated GWAs variants remains a key challenge to translating the findings from GWAs to therapeutic treatments. Defining the causal mechanisms behind the variants require functional screening experiments that can be complex and costly. Prioritising variants for functional characterisation using techniques that capture important functional and regulatory elements can assist this. The genetic architectu...
3 CitationsSource
#1W. GuoH-Index: 1
#2Y.M. LenighanH-Index: 3
Last.Fiona C. McGillicuddyH-Index: 19
view all 12 authors...
Source
#2Jessica C. RalstonH-Index: 8
Last.Helen M. RocheH-Index: 53
view all 9 authors...
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#1Anna M. Kirwan (UCD: University College Dublin)H-Index: 3
#2Y.M. Lenighan (UCD: University College Dublin)H-Index: 3
Last.Helen M. Roche (UCD: University College Dublin)H-Index: 53
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Metabolic inflammation is a very topical area of research, wherein aberrations in metabolic and inflammatory pathways probably contribute to atherosclerosis, insulin resistance (IR) and type 2 diabetes. Metabolic insults arising from obesity promote inflammation, which in turn impedes insulin signalling and reverse cholesterol transport (RCT). Key cells in the process are metabolically activated macrophages, which up-regulate both pro- and anti-inflammatory pathways in response to lipid spillove...
16 CitationsSource
#1Y.M. Lenighan (UCD: University College Dublin)H-Index: 3
#2Anne P. Nugent (UCD: University College Dublin)H-Index: 18
Last.Breige A. McNulty (UCD: University College Dublin)H-Index: 11
view all 8 authors...
Irish Department of Agriculture, Food and the Marine (under the National Development Plan (2007–2013) (grant no. 13/F/514)); Health Research Board (under their joint Food for Health Research Initiative (2007–2012) (grant no. FHRIUCC2))
7 CitationsSource
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