Match!
Eleftherios P. Diamandis
Mount Sinai Hospital, Toronto
1,112Publications
97H-index
39.4kCitations
Publications 1112
Newest
Published on Dec 1, 2019in Clinical Proteomics2.89
Milena Music (U of T: University of Toronto), Antoninus Soosaipillai35
Estimated H-index: 35
(MSH: Mount Sinai Hospital, Toronto)
+ 3 AuthorsEleftherios P. Diamandis97
Estimated H-index: 97
Background Autoantibodies are produced when tolerance to self-antigens is broken and they can be mediators of tissue injury and systemic inflammation. They are excellent biomarkers because they are minimally invasive to screen and are highly abundant in serum due to limited proteolysis and slow clearance. Conventionally used methods of identifying autoantibodies in patient sera include indirect immunofluorescence, enzyme-linked immunoabsorbent assays (ELISAs) and protein microarrays. Here we pre...
Published on 2019in BMC Medicine8.29
Clare Fiala3
Estimated H-index: 3
(MSH: Mount Sinai Hospital, Toronto),
Eleftherios P. Diamandis97
Estimated H-index: 97
(U of T: University of Toronto)
Published on Dec 1, 2019in BMC Cancer2.93
Weiwei Gong (TUM: Technische Universität München), Yueyang Liu1
Estimated H-index: 1
(TUM: Technische Universität München)
+ 6 AuthorsJulia Dorn14
Estimated H-index: 14
(TUM: Technische Universität München)
Background In ovarian cancer, dysregulation of mRNA expression of several components of the family of the kallikrein-related peptidases (KLKs) is observed. In this study, we have analyzed the KLK5 mRNA expression pattern in tumor tissue of patients suffering from high-grade serous ovarian cancer stage FIGO III/IV. Moreover, we have correlated the KLK5 mRNA levels with clinical outcome.
Published on Dec 1, 2019in Translational neurodegeneration
Oliver Goldhardt1
Estimated H-index: 1
(TUM: Technische Universität München),
Inanna Warnhoff (TUM: Technische Universität München)+ 7 AuthorsTimo Grimmer31
Estimated H-index: 31
(TUM: Technische Universität München)
Alterations in the expression of human kallikrein-related peptidases (KLKs) have been described in patients with Alzheimer’s disease (AD). We elucidated the suitability of KLK6, KLK8 and KLK10 to distinguish AD from NC and explored associations with established AD biomarkers. KLK levels in cerebrospinal fluid (CSF), as determined by ELISA, were compared between 32 AD patients stratified to A/T/(N) system with evidence for amyloid pathology and of 23 normal controls with normal AD biomarkers. Ass...
Published on Dec 1, 2019in Clinical Proteomics2.89
Shalini M. Mahendran (U of T: University of Toronto), E. Keystone25
Estimated H-index: 25
(MSH: Mount Sinai Hospital, Toronto)
+ 3 AuthorsVinod Chandran34
Estimated H-index: 34
Background Inflammatory arthritis (IA) is an immunological disorder in which loss of immune tolerance to endogenous self-antigens perpetuates synovitis and eventual destruction of the underlying cartilage and bone. Pathological changes in the joint are expected to be represented by synovial fluid (SF) proteins and peptides. In the present study, a mass spectrometry-based approach was utilized for the identification of key protein and peptide mediators of IA.
Published on Jan 18, 2019in BMC Medicine8.29
Clare Fiala3
Estimated H-index: 3
(Mount Sinai Hospital),
Eleftherios P. Diamandis97
Estimated H-index: 97
Where should I submit my paper? This is a question that young scientists and trainees frequently ask. In this Commentary, we advise on how to make such a decision whilst balancing the risks and benefits. We argue that trying to publish in top tier journals may not always be the best option and that publishing in indexed, open access journals may expose research to the same or larger audiences. The value of research should not be judged according to the publishing journal’s name, but rather from ...
Published on 2019in F1000Research
Michelle B. Chen9
Estimated H-index: 9
(U of T: University of Toronto),
Antoninus Soosaipillai35
Estimated H-index: 35
(MSH: Mount Sinai Hospital, Toronto)
+ 1 AuthorsEleftherios P. Diamandis97
Estimated H-index: 97
Background: Traumatic brain injury (TBI) is a major cause of death and disability. Despite increased awareness, reliable biomarkers are urgently needed to aid in all forms of traumatic brain injury diagnosis and prognosis. Methods: Here, we aim to assess the diagnostic utility of known and novel TBI biomarkers in a pilot patient cohort of severe TBI (sTBI) patients and healthy controls. We analyzed concentrations of S100 calcium binding protein B (S100B), neuron specific enolase (NSE), human kal...
Published on Mar 26, 2019in Clinical Chemistry and Laboratory Medicine3.64
Clare Fiala3
Estimated H-index: 3
,
Jennifer Taher6
Estimated H-index: 6
,
Eleftherios P. Diamandis97
Estimated H-index: 97
12345678910