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S. De Saeger
Ghent University
416Publications
42H-index
6,607Citations
Publications 418
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#1Sefater Gbashi (UJ: University of Johannesburg)H-Index: 4
#2Patrick Berka Njobeh (UJ: University of Johannesburg)H-Index: 12
Last.Ntakadzeni Edwin Madala (UNIVEN: University of Venda)H-Index: 1
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Abstract Effective management of mycotoxins rely on stringent regulation and routine surveillance of food/feed commodities via efficient analysis, hence the continuous need for improved methods. The present study developed, optimized and validated a modified pressurized hot water extraction (PHWE) method for the simultaneous extraction of multi-mycotoxins from maize and subsequent quantification on LC-MS/MS. The PHWE system was modified using ethanol (EtOH) as a cosolvent, while a numerical mode...
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#1Mohamed F. Abdallah (UGent: Ghent University)H-Index: 4
#2Kris Audenaert (UGent: Ghent University)H-Index: 23
Last.S. De Saeger (UGent: Ghent University)H-Index: 42
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Abstract Sugarcane juice is a traditional drink consumed on a daily basis in Egypt. The current work was conducted to (1) evaluate the multi-mycotoxin contamination in sugarcane juice, (2) identify the profiles of the mycotoxigenic fungi, and (3) assess the risk of mycotoxin exposure among the adult population. Sugarcane juice samples (n = 89) were randomly collected in two seasons from Egypt. Quantification of 13 mycotoxins was done through a validated LC-MS/MS method. The isolated fungal speci...
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Age-related differences in toxicokinetic processes of deoxynivalenol (DON) and deoxynivalenol-3-glucoside (DON3G) were studied. DON3G [55.7 µg/kg bodyweight (BW)] and an equimolar dose of DON (36 µg/kg BW) were administered to weaned piglets (4 weeks old) by single intravenous and oral administration in a double two-way cross-over design. Systemic and portal blood was sampled at different time points pre- and post-administration and plasma concentrations of DON, DON3G and their metabolites were ...
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#1Alina A. Kokorina (SGU: Saratov State University)H-Index: 2
#2Artem A. Bakal (SGU: Saratov State University)H-Index: 1
Last.Irina Yu. Goryacheva (SGU: Saratov State University)H-Index: 19
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We investigated light emission of hydrothermally treated citric acid and ethylenediamine (EDA) with various precursor ratios using gel-electrophoresis. We show that this relatively simple approach can deliver significant insights into the origins of photoluminescence. We found that products of the synthesis consist of both positively and negatively charged species and exhibit large dispersion in electrophoretic mobility (i.e. charge-to-size ratio). We observed that despite the large dispersion o...
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#1Daniil D. Drozd (SGU: Saratov State University)H-Index: 1
#2Huiyan Zhang (UGent: Ghent University)H-Index: 10
Last.Natalia V. Beloglazova (UGent: Ghent University)H-Index: 12
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Abstract Here we report the facile strategies for synthesis of silica-coated quantum dots (QDs). Due to their small size, chemical and optical stability and high luminescence quantum yield these particles can be further applicable in chemical and biomedical analysis, and in vivo imaging. The article gives a structured and detailed overview of the silanization strategies and potential pitfalls and common technical issues in function of the stability of the obtaining QDs. Different types of QDs, I...
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Fusarium mycotoxins and their derivatives are frequently detected in freshly harvested forage maize. This study assessed the time course effects during ensiling of forage maize on the fate of Fusarium mycotoxins, using laboratory-scale silos and artificially contaminated raw material. A multi-mycotoxin liquid chromatography–high-resolution mass spectrometry (LC-HRMS) method was used to determine the levels of deoxynivalenol (DON), zearalenone (ZEN) and their derivatives DON-3-glucoside, 3-acetyl...
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AbstractThe aim of this study was to systematically review associations between dietary mycotoxins exposure and child growth and morbidity of children aged 5 years or younger. Peer-reviewed literat...
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Zearalenone-14-glucoside (ZEN-14G), a key modified mycotoxin, has attracted a great deal of attention due to the possible conversion to its free form of zearalenone (ZEN) exerting toxicity. In this study, the toxicokinetics of ZEN-14G were investigated in rats after oral and intravenous administration. The plasma concentrations of ZEN-14G and its major five metabolites were quantified using a validated liquid chromatography tandem mass spectrometry (LC-MS/MS) method. The data were analyzed via n...
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Abstract Biomarker-driven research has been proposed as a successful method to assess the exposure of individuals to xenobiotics, including mycotoxins, through estimation of their metabolites in biological fluids. A methodology to determine patulin (PAT) and citrinin (CIT) in human urine and plasma using liquid chromatography coupled to tandem mass spectrometry was developed and validated in the present study. Selectivity/specificity, linearity, limit of detection and quantification, apparent re...
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