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Ainara Estanga
Mayo Clinic
Publications 28
Published on Apr 1, 2019in Nature Reviews Neuroscience 32.63
Yaakov Stern125
Estimated H-index: 125
(Columbia University),
Gaël Chételat10
Estimated H-index: 10
(French Institute of Health and Medical Research)
+ 23 AuthorsJeremy A. Elman10
Estimated H-index: 10
(UCSD: University of California, San Diego)
1 Citations Source Cite
Published on Sep 1, 2018in Alzheimers & Dementia 12.76
Yaakov Stern125
Estimated H-index: 125
(Columbia University),
Eider M. Arenaza-Urquijo1
Estimated H-index: 1
(Mayo Clinic)
+ 31 AuthorsWilliam S. Kremen51
Estimated H-index: 51
(UCSD: University of California, San Diego)
Abstract Several concepts, which in the aggregate get might be used to account for "resilience" against age- and disease-related changes, have been the subject of much research. These include brain reserve, cognitive reserve, and brain maintenance. However, different investigators have use these terms in different ways, and there has never been an attempt to arrive at consensus on the definition of these concepts. Furthermore, there has been confusion regarding the measurement of these construct...
17 Citations Source Cite
Published on Sep 1, 2018in Brain and behavior 2.22
Alle Meije Wink21
Estimated H-index: 21
(VU: VU University Amsterdam),
Betty M. Tijms4
Estimated H-index: 4
(VU: VU University Amsterdam)
+ 12 AuthorsMaite García-Sebastián9
Estimated H-index: 9
Introduction: Amyloid plaque deposition in the brain is an early pathological change in Alzheimer's disease (AD), causing disrupted synaptic connections. Brain network disruptions in AD have been demonstrated with eigenvector centrality (EC), a measure that identifies central regions within networks. Carrying an apolipoprotein (APOE)-e4 allele is a genetic risk for AD, associated with increased amyloid deposition. We studied whether APOE-e4 carriership is associated with EC disruptions in cognit...
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Published on Jul 17, 2018in Neurology 8.05
Mirian Ecay-Torres4
Estimated H-index: 4
Ainara Estanga10
Estimated H-index: 10
+ 10 AuthorsArantzazu Arrospide11
Estimated H-index: 11
Objective To investigate the cognitive profile of healthy individuals with increased Cardiovascular Risk Factors, Aging and Dementia (CAIDE) dementia risk score and to explore whether this association is related to vascular burden and CSF biomarkers of amyloidosis and neurodegeneration. Method Cognitively normal participants (mean age 57.6 years) from the Gipuzkoa Alzheimer Project study were classified as having high risk (HR; n = 82) or low risk (LR; n = 293) for dementia according to a CAIDE ...
1 Citations Source Cite
Published on Jun 25, 2018in Frontiers in Aging Neuroscience 3.58
Isabelle Bos3
Estimated H-index: 3
(UM: Maastricht University),
Stephanie J.B. Vos13
Estimated H-index: 13
(UM: Maastricht University)
+ 21 AuthorsAlberto Lleó31
Estimated H-index: 31
We investigated whether amyloid-β (Aβ) and tau affected cognition in cognitively normal (CN) individuals, and whether norms for neuropsychological tests based on biomarker-negative individuals would improve early detection of dementia. We included 907 CN individuals from 8 European cohorts and from the Alzheimer’s disease Neuroimaging Initiative. All individuals were aged above 40, had Aβ status and neuropsychological data available. Linear mixed models were used to assess the associations of Aβ...
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Published on Oct 1, 2017in Alzheimers & Dementia 12.76
Victor Montal6
Estimated H-index: 6
(Autonomous University of Barcelona),
Eduard Vilaplana8
Estimated H-index: 8
(Autonomous University of Barcelona)
+ 27 AuthorsEstrella Morenas-Rodríguez8
Estimated H-index: 8
(Autonomous University of Barcelona)
Abstract Introduction Cortical mean diffusivity (MD) and free water fraction (FW) changes are proposed biomarkers for Alzheimer's disease (AD). Methods We included healthy control subjects (N = 254), mild cognitive impairment (N = 41), and AD dementia (N = 31) patients. Participants underwent a lumbar puncture and a 3 T magnetic resonance imaging. Healthy control subjects were classified following National Institute on Aging-Alzheimer's Association stages (stage 0, N=220; stage 1, N=25; and stag...
8 Citations Source Cite
Published on Jul 1, 2017
Karmele López-de-Ipiña11
Estimated H-index: 11
(UPV/EHU: University of the Basque Country),
U. Martinez-de-Lizarduy2
Estimated H-index: 2
(UPV/EHU: University of the Basque Country)
+ 5 AuthorsMarcos Faundez-Zanuy27
Estimated H-index: 27
The so-called Mild Cognitive Impairment (MCI) or cognitive loss appears in a previous stage before Alzheimer’s Disease (AD), but it does not seem sufficiently severe to interfere in independent abilities of daily life, so it usually does not receive an appropriate diagnosis. Its detection is a challenging issue to be addressed by medical specialists. This work presents a novel proposal based on automatic analysis of speech and disfluencies aimed at supporting MCI diagnosis. The approach includes...
2 Citations Source Cite