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Rupa Bhowmick
Council of Scientific and Industrial Research
Antifreeze proteinIce bindingEffectorBioinformaticsBiology
5Publications
1H-index
2Citations
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Publications 5
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#1Rupa Bhowmick (CSIR: Council of Scientific and Industrial Research)H-Index: 1
#2Piyali Ganguli (CSIR: Council of Scientific and Industrial Research)H-Index: 2
Last. Ram Rup Sarkar (CSIR: Council of Scientific and Industrial Research)H-Index: 18
view all 3 authors...
Different types of T effector cells function centrally in the immune-regulatory network, which acts as a line of defense for the body and elicits immune response during any diseased condition. At the molecular level, this functioning is maintained by an intricately designed network of signaling and metabolic pathways that function via multiple cross-talks to regulate complex immune responses during different antigenic challenges. These pathways regulate phenomena such as quiescence exit of naive...
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#1Saikat ChowdhuryH-Index: 4
#2Noopur SinhaH-Index: 1
Last. Ram Rup SarkarH-Index: 18
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#1Rupa Bhowmick (CSIR: Council of Scientific and Industrial Research)H-Index: 1
#2Abhishek Subramanian (CSIR: Council of Scientific and Industrial Research)H-Index: 5
Last. Ram Rup Sarkar (CSIR: Council of Scientific and Industrial Research)H-Index: 5
view all 3 authors...
Brain cancers demonstrate a complex metabolic behavior so as to adapt the external hypoxic environment and internal stress generated by reactive oxygen species. To survive in these stringent conditions, glioblastoma cells develop an antagonistic metabolic phenotype as compared to their predecessors, the astrocytes, thereby quenching the resources expected for nourishing the neurons. The complexity and cumulative effect of the large scale metabolic functioning of glioblastoma is mostly unexplored...
1 CitationsSource
#1Piyali Ganguli (CSIR: Council of Scientific and Industrial Research)H-Index: 2
#2Saikat Chowdhury (CSIR: Council of Scientific and Industrial Research)H-Index: 4
Last. Ram Rup Sarkar (CSIR: Council of Scientific and Industrial Research)H-Index: 18
view all 4 authors...
Various T-cell co-receptor molecules and calcium channel CRAC play a pivotal role in the maintenance of cell’s functional responses by regulating the production of effector molecules (mostly cytokines) that aids in immune clearance and also maintaining the cell in a functionally active state. Any defect in these co-receptor signalling pathways may lead to an altered expression pattern of the effector molecules. To study the propagation of such defects with time and their effect on the intracellu...
1 CitationsSource
#1Rachana Banerjee (CU: University of Calcutta)H-Index: 4
#2Pratim ChakrabortiH-Index: 1
Last. Subhasish Mukhopadhyay (CU: University of Calcutta)H-Index: 2
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Antifreeze proteins or ice-binding proteins (IBPs) facilitate the survival of certain cellular organisms in freezing environment by inhibiting the growth of ice crystals in solution. Present study identifies orthologs of the IBP of Colwellia sp. SLW05, which were obtained from a wide range of taxa. Phylogenetic analysis on the basis of conserved regions (predicted as the ‘ice-binding domain’ [IBD]) present in all the orthologs, separates the bacterial and archaeal orthologs from that of the euka...
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