Jeong-Hoon Lee
Seoul National University
VirologyHepatitis BHepatocellular carcinomaHepatitis B virusMedicine
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Publications 250
#1Ju-Yeon Cho (Chosun University)H-Index: 4
#2Soon Sun Kim (Ajou University)H-Index: 14
Last. Jihoon Kim (KU: Korea University)H-Index: 50
view all 6 authors...
#1Jeong-Hoon Lee (SNU: Seoul National University)H-Index: 24
#2Yun Bin Lee (SNU: Seoul National University)H-Index: 12
Last. Yoon Jun Kim (SNU: Seoul National University)H-Index: 39
view all 6 authors...
BACKGROUND HBsAg seroclearance is considered a functional cure for patients with chronic hepatitis B, but is rarely achievable with oral nucleos(t)ide analogs alone. We conducted a randomized controlled proof-of-concept trial to evaluate the impact of adding pegylated interferon (Peg-IFN) alfa-2a plus sequential or concomitant hepatitis B virus (HBV) vaccination. METHODS A total of 111 patients who achieved serum HBV DNA <20 IU/mL and quantitated HBsAg (qHBsAg) <3,000 IU/mL with entecavir were r...
#1Joon Yeul Nam (Ewha Womans University)H-Index: 5
#2A. Reum Choe (Ewha Womans University)
Last. Jin Wook Chung (SNU: Seoul National University)H-Index: 54
view all 16 authors...
The decision of transarterial chemoembolization (TACE) initiation and/or repetition remains challenging in patients with unresectable hepatocellular carcinoma (HCC). The aim was to develop a prognostic scoring system to guide TACE initiation/repetition. A total of 597 consecutive patients who underwent TACE as their initial treatment for unresectable HCC were included. We derived a prediction model using independent risk factors for overall survival (OS), which was externally validated in an ind...
#1Cheol-Hyung Lee (SNU: Seoul National University)
#2Yun Bin Lee (SNU: Seoul National University)H-Index: 12
Last. Su Jong Yu (SNU: Seoul National University)H-Index: 22
view all 13 authors...
Background/Aims Several treatment options are currently available for patients with hepatocellular carcinoma (HCC) failing previous sorafenib treatment. We aimed to compare the effectiveness of regorafenib and nivolumab in these patients. Methods Consecutive HCC patients who received regorafenib or nivolumab after failure of sorafenib treatment were included. Primary endpoint was overall survival (OS) and secondary endpoints were time to progression, tumor response rate, and adverse events. Inve...
#1Yoo Je (SCH: Soonchunhyang University)H-Index: 1
#1Jeong Ju Yoo (SCH: Soonchunhyang University)H-Index: 12
Last. Jung-Hwan Yoon (SNU: Seoul National University)H-Index: 46
view all 9 authors...
Background/Aims: Patients with an intermediate stage of hepatocellular carcinoma (HCC) represent a highly heterogeneous population; therefore, many models have been proposed to predict the survival of these patients. The aim of this study was to evaluate the prognostic performance of a novel subclassification for tumors classified as Barcelona Clinic Liver Cancer (BCLC) stage B using the Model to Estimate Survival in Ambulatory HCC patients (MESIAH). Methods: This analysis was based on 377 patie...
1 CitationsSource
#1Injoon Yeo (SNU: Seoul National University)H-Index: 1
#2Gi‐Ae Kim (Kyung Hee University)H-Index: 1
Last. Youngsoo KimH-Index: 39
view all 9 authors...
There is an urgent need for new biomarkers that address the shortcomings of current screening methods which fail to detect a large proportion of cases with hepatocellular carcinoma (HCC) at early stage. To develop a robust, multiple-biomarker panel based on multiple reaction monitoring-mass spectrometry with high performance in detecting early-stage HCC within at-risk populations. In the discovery set, 150 samples were analyzed to identify candidate biomarkers. The resulting list of candidates w...
#1Hyue Mee Kim (CAU: Chung-Ang University)
#1Hyue Mee Kim (Seoul National University Hospital)H-Index: 3
Last. Jung-Hwan Yoon (SNU: Seoul National University)H-Index: 46
view all 11 authors...
BACKGROUND: Cardiac dysfunction is increasingly recognized in patients with liver cirrhosis. Nevertheless, the presence or absence of structural alterations such as diffuse myocardial fibrosis remains unclear. We aimed to investigate myocardial structural changes in cirrhosis, and explore left ventricular (LV) structural and functional changes induced by liver transplantation. METHODS: This study included 33 cirrhosis patients listed for transplantation and 20 healthy controls. Patients underwen...
#1Jae Seok Bae (Seoul National University Hospital)H-Index: 4
#2Deok Hee Lee (Seoul National University Hospital)H-Index: 52
Last. Byung Ihn Choi (CAU: Chung-Ang University)H-Index: 67
view all 10 authors...
PURPOSE: To assess the diagnostic performance of the normalized local variance (NLV) ultrasound technique in the detection of the fatty liver using histopathology as a reference standard. MATERIALS AND METHODS: We prospectively enrolled 194 consecutive patients with clinical suspicion of diffuse liver disease or history of liver transplantation. Conventional grayscale ultrasound and NLV examinations were performed and immediately followed by liver biopsies. The degrees of fatty liver, necroinfla...
#1Young Youn Cho (CAU: Chung-Ang University)H-Index: 11
#2Su Jong YuH-Index: 22
Last. Jung-Hwan YoonH-Index: 46
view all 11 authors...
Background/Aims:Transarterial chemoembolization (TACE) is a major therapeutic modality for patients with unresectable hepatocellular carcinoma, which needs repeated treatments. Model to Estimate Survival in Ambulatory Hepatocellular carcinoma patients (MESIAH) was recently developed as a model for p