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Thomas Morville
University of Copenhagen
EndocrinologyStatinDiabetes mellitusMedicineEndurance training
14Publications
3H-index
39Citations
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Publications 16
Newest
#1Jens Friis Lund (UCPH: University of Copenhagen)H-Index: 23
#2Camilla Lund (UCPH: University of Copenhagen)H-Index: 1
Last. Christoffer Clemmensen (UCPH: University of Copenhagen)H-Index: 22
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Human biology has evolved to keep body fat within a range that supports survival. During the last 25 years, obesity biologists have uncovered key aspects of physiology that prevent fat mass from becoming too low. In contrast, the mechanisms that counteract excessive adipose expansion are largely unknown. Evidence dating back to the 1950s suggests the existence of a blood-borne molecule that defends against weight gain. In this article, we discuss the research supporting an “unidentified factor o...
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#1Maria Hansen (UCPH: University of Copenhagen)H-Index: 3
#2Anja Birk Kuhlman (UCPH: University of Copenhagen)H-Index: 4
Last. Flemming Dela (UCPH: University of Copenhagen)H-Index: 47
view all 10 authors...
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#1Anja Birk Kuhlman (UCPH: University of Copenhagen)H-Index: 4
#2Thomas Morville (UCPH: University of Copenhagen)H-Index: 3
Last. Flemming Dela (UCPH: University of Copenhagen)H-Index: 47
view all 7 authors...
Simvastatin is a cholesterol-lowering drug that is prescribed to lower the risk of cardiovascular disease following high levels of blood cholesterol. There is a possible risk of new onset diabetes mellitus with statin treatment but the mechanisms behind are unknown. Coenzyme Q10 (CoQ10) supplementation has been found to improve glucose homeostasis in various patient populations and may increase muscle GLUT4 content. Our aim was to investigate whether eight weeks of CoQ10 supplementation can impr...
1 CitationsSource
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#1Tine Lovsø Dohlmann (UCPH: University of Copenhagen)H-Index: 4
#2Thomas Morville (UCPH: University of Copenhagen)H-Index: 3
Last. Steen Larsen (UCPH: University of Copenhagen)H-Index: 28
view all 7 authors...
1 CitationsSource
#1Thomas Morville (UCPH: University of Copenhagen)H-Index: 3
#2Tine Lovsø Dohlmann (UCPH: University of Copenhagen)H-Index: 4
Last. Flemming Dela (UCPH: University of Copenhagen)H-Index: 47
view all 10 authors...
Source
#1Maria Hansen (UCPH: University of Copenhagen)H-Index: 3
#2Anja Birk Kuhlman (UCPH: University of Copenhagen)H-Index: 4
Last. Flemming Dela (UCPH: University of Copenhagen)H-Index: 47
view all 10 authors...
Abstract Purpose Atherosclerosis is a major risk factor for cardiovascular disease (CVD) and is known to be an inflammatory process. Statin therapy decreases both cholesterol and inflammation and is used in primary and secondary prevention of CVD. However, a statin induced decrease of plasma concentrations of the antioxidant coenzyme Q10 (CoQ10), may prevent the patients from reaching their optimal anti-inflammatory potential. Here, we studied the anti-inflammatory effect of Simvastatin therapy ...
3 CitationsSource
#1Ronni E. Sahl (UCPH: University of Copenhagen)H-Index: 3
#2Thomas Morville (UCPH: University of Copenhagen)H-Index: 3
Last. Steen Larsen (UCPH: University of Copenhagen)H-Index: 28
view all 6 authors...
Abstract Skeletal muscle is a heterogeneous tissue and it is essential to know the methodological variation and reliability when measuring aspects of muscle function. We assessed the methodological and biological variation when measuring mitochondrial respiratory capacity (MRC), citrate synthase (CS) activity and myosin heavy chain (MHC) composition in muscle biopsies from nine healthy male participants, and in addition we assessed variation in MRC in isolated mitochondria and yeast suspension. ...
1 CitationsSource
#1Thomas MorvilleH-Index: 3
#2Ronni E. SahlH-Index: 3
Last. Christoffer ClemmensenH-Index: 22
view all 7 authors...
6 CitationsSource
#1Thomas Morville (UCPH: University of Copenhagen)H-Index: 3
#2Mads Rosenkilde (UCPH: University of Copenhagen)H-Index: 12
Last. Hanne Rasmusen (UCPH: University of Copenhagen)H-Index: 5
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ABSTRACTObjectives: Physiological effects of exercise on trained and untrained individuals have been studied extensively. Typically, young or middle-aged individuals are examined before and after short periods of vigorous exertion.Methods: We studied 6 elderly male athletes (61 ± 8 years (mean ± SD); baseline O2max 48 ± 5 ml·kg−1·min−1) with focus on cardiac function and biomarkers following 14 consecutive days of moderate intensity exercise. Cardiac dimensions, function, biomarkers, and other m...
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