Alexander Lammert
Heidelberg University
EndocrinologyProspective cohort studyType 2 diabetesDiabetes mellitusMedicine
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Publications 39
#1Ulf Elbelt (Charité)H-Index: 15
#2Sven Schlaffer (FAU: University of Erlangen-Nuremberg)H-Index: 12
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#1Graciela Delgado (Heidelberg University)H-Index: 20
#2Bernhard K. Krämer (Heidelberg University)H-Index: 47
Last. Alexander Lammert (Heidelberg University)H-Index: 10
view all 8 authors...
#1Graciela Delgado (Heidelberg University)H-Index: 20
#2Marcus E. Kleber (Heidelberg University)H-Index: 51
Last. Alexander Lammert (Heidelberg University)H-Index: 10
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Background In a pilot study, we evaluated the efficacy of two days of oatmeal on insulin resistance and glucose metabolism and found a marked decrease of insulin requirements. The most important shortcoming of that study was that the interventions were not isocaloric (diabetes adapted diet: 1500 kcal/d vs. oatmeal 1100 kcal/d). To address these drawbacks we designed the OatMeal And Insulin Resistance (OMA-IR) study. Methods The study was a randomized, open label crossover dietary intervention st...
2 CitationsSource
#1Shiqi Zhang (Anhui Medical University)H-Index: 4
#2Thomas Albrecht (Heidelberg University)H-Index: 3
Last. Sibylle J. Hauske (Heidelberg University)H-Index: 5
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This study assessed if serum carnosinase (CNDP1) activity and concentration in patients with type 2 diabetes mellitus (T2D) with diabetic nephropathy (DN) differs from those without nephropathy. In a cross-sectional design 127 patients with T2D with DN ((CTG)5 homozygous patients n = 45) and 145 patients with T2D without nephropathy ((CTG)5 homozygous patients n = 47) were recruited. Univariate and multivariate regression analyses were performed to predict factors relevant for serum CNDP1 concen...
#1Myriam RheinbergerH-Index: 5
#2Bettina JungH-Index: 6
Last. Carsten A. BögerH-Index: 20
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#1Alexander Lammert (Heidelberg University)H-Index: 10
#2Marc Sebastian Walter (Heidelberg University)H-Index: 1
Last. Marcel Seiz-Rosenhagen (Heidelberg University)H-Index: 8
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Objective Pituitary apoplexy is a serious medical complication of a pre-existing pituitary adenoma characterized by a variety of clinical symptoms ranging from mild headache to neurologically impaired and finally comatose patients. Management options are surgery or conservative treatment (e. g., with dexamethasone). Surgery is commonly performed in case of severe acute neurological and visual symptoms. However, prospective studies demonstrating a benefit of surgery over conservative treatment in...
2 CitationsSource
#1Juri Mattern (Heidelberg University)
#2Alexander Lammert (Heidelberg University)H-Index: 10
Last. Hans-Peter Hammes (Heidelberg University)H-Index: 42
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Objective To assess retinopathy and its risk factors in an obesity WHO III cohort. Methods In the Mannheim Obesity Study , 277 subjects with obesity WHO III aged 18–64 years were examined in a cross-sectional approach. Screening for retinopathy was performed using 3-field retinal photography. Endothelial function was assessed using arteriole-to-venule ratio and flicker light analysis. Subjects with and without retinopathy were analysed for anthropometry, metabolic, vascular and renal parameters....
#1Thomas Albrecht (Heidelberg University)H-Index: 3
#2Shiqi Zhang (Anhui Medical University)H-Index: 4
Last. Sibylle J. Hauske (Heidelberg University)H-Index: 5
view all 16 authors...
Considering that the homozygous CNDP1 (CTG)5 genotype affords protection against diabetic nephropathy (DN) in female patients with type 2 diabetes, this study assessed if this association remains gender-specific when applying clinical inclusion criteria (CIC-DN) or biopsy proof (BP-DN). Additionally, it assessed if the prevalence of the protective genotype changes with diabetes duration and time on hemodialysis and if this occurs in association with serum carnosinase (CN-1) activity. Whereas the...
5 CitationsSource
#1Heiko M. Mundt (Heidelberg University)H-Index: 4
#2Matthias Matenaer (Heidelberg University)H-Index: 1
Last. Urs Benck (Heidelberg University)H-Index: 12
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Resistant hypertension is still a challenge and reserve antihypertensive agents are often necessary to achieve blood pressure control. One reserve antihypertensive is minoxidil, a direct vasodilator that is known for its strong blood pressure–lowering effect, but contemporary studies are sparse. The authors retrospectively analyzed 54 inpatients with uncontrolled hypertension despite the combined use of current antihypertensive agents. To investigate the effect of minoxidil when added to other a...
5 CitationsSource