Michael Korzinkin
Publications 3
#1Vassiliki SalouraH-Index: 13
#2Evgeny Izumchenko (U of C: University of Chicago)H-Index: 12
Last.Tanguy Y. Seiwert (U of C: University of Chicago)H-Index: 37
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Abstract Objectives In this study we describe the tumor microenvironment, the signaling pathways and genetic alterations associated with the presence or absence of CD8+ T-cell infiltration in primary squamous cell carcinoma of the head and neck (SCCHN) tumors. Materials and Methods Two SCCHN multi-analyte cohorts were utilized, the Cancer Genome Atlas (TCGA) and the Chicago Head and Neck Genomics (CHGC) cohort. A well-established chemokine signature classified SCCHN tumors into high and low CD8+...
1 CitationsSource
#1Alexander AliperH-Index: 20
#2Michael KorzinkinH-Index: 2
Last.Nikolay M. Borisov (Kurchatov Institute)H-Index: 14
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13 CitationsSource
#1Artem ArtemovH-Index: 10
#2Alexander AliperH-Index: 20
Last.Anton BuzdinH-Index: 26
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A new generation of anticancer therapeutics called target drugs has quickly developed in the 21 st century. These drugs are tailored to inhibit cancer cell growth, proliferation, and viability by specific interactions with one or a few target proteins. However, despite formally known molecular targets for every “target” drug, patient response to treatment remains largely individual and unpredictable. Choosing the most effective personalized treatment remains a major challenge in oncology and is ...
25 CitationsSource