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Shuxia Li
University of Southern Denmark
50Publications
10H-index
246Citations
Publications 50
Newest
#1Jesper Lund (University of Southern Denmark)H-Index: 2
#2Shuxia Li (University of Southern Denmark)H-Index: 10
Last.Qihua Tan (University of Southern Denmark)H-Index: 32
view all 11 authors...
Background Multiple epigenome-wide association studies have been performed to identify DNA methylation patterns regulated by aging or correlated with risk of death. However, the inter-relatedness of the epigenetic basis of aging and mortality has not been well investigated.
3 CitationsSource
#1Afsaneh Mohammadnejad (University of Southern Denmark)H-Index: 1
#2Shuxia Li (University of Southern Denmark)H-Index: 10
Last.Qihua Tan (University of Southern Denmark)H-Index: 32
view all 4 authors...
Abstract Electroacupuncture (EA) has been extensively considered as a tool for treating diseases and relieving various pains. However, understanding the molecular mechanisms underlying its effect is of high importance. In this study, we performed a weighted gene co-expression network analysis (WGCNA) on data collected from a microarray experiment to investigate the relationship underlying EA within three factors, time, frequency and tissue regions (periaqueductal grey (PAG) and spinal dorsal hor...
Source
#1Vibe Maria Jacobsen (University of Southern Denmark)H-Index: 1
#2Shuxia LiH-Index: 10
Last.Qihua Tan (University of Southern Denmark)H-Index: 32
view all 8 authors...
AbstractPolycystic ovarian syndrome (PCOS) is a complex disorder affecting up to 15–20% of reproductive women. PCOS has recently been investigated using genome-wide association studies revealing im...
1 CitationsSource
#1Shuxia Li (University of Southern Denmark)H-Index: 10
#2Jesper Lund (University of Southern Denmark)H-Index: 2
Last.Qihua Tan (University of Southern Denmark)H-Index: 32
view all 11 authors...
BackgroundMultiple epigenetic association studies on human aging have been performed reporting large numbers of sites differentially methylated across ages on the autosomal chromosomes. The X-chromosome has been studied little, due to analytical difficulties in dealing with sex differences in X-chromosome content and X-inactivation in females. Based on large collections of genome-wide DNA methylation data on two Danish cohorts of identical twins (mean ages, 66 and 79 years) and the Lothian Birth...
Source
#1Qihua Tan (University of Southern Denmark)H-Index: 32
#2Hongmei Duan (UCPH: University of Copenhagen)H-Index: 3
Last.Shuxia Li (University of Southern Denmark)H-Index: 10
view all 5 authors...
Abstract Purpose Although moderate to high genetic contribution to blood pressure variation have been estimated in numerous studies, the genetic control over the longitudinal change in blood pressure has been less frequently investigated because of the requirement of longitudinal design. Methods Based on blood pressure data from a large-scale family-based longitudinal survey, we introduced hierarchical modeling of longitudinal family data in combination with fractional polynomials for fitting no...
Source
#1Jesper Lund (University of Southern Denmark)H-Index: 2
#2Shuxia Li (University of Southern Denmark)H-Index: 10
Last.Qihua Tan (University of Southern Denmark)H-Index: 32
view all 11 authors...
2 CitationsSource
#1Haiping Duan (KI: Karolinska Institutet)H-Index: 6
#2Dongfeng Zhang (Qingdao University)H-Index: 18
Last.Chengxuan Qiu (KI: Karolinska Institutet)H-Index: 40
view all 10 authors...
Source
#1Tong Wang (Qingdao University)H-Index: 3
#2Yili Wu (Qingdao University)H-Index: 10
Last.Qihua Tan (University of Southern Denmark)H-Index: 32
view all 8 authors...
Objectives To estimate the effects of baseline grip strength and cognition on the trajectory of functional limitation over time. Design Longitudinal study of older adults participating in the Survey of Health, Ageing and Retirement in Europe (SHARE). Setting Urban and rural households in 11 European countries and Israel. Participants Individuals aged 50 and older from SHARE (2004–2015) (N=14,073; 52.5% female). Measurements Outcomes were functional limitation scores from five panel wave. Main ex...
4 CitationsSource
#1Qihua TanH-Index: 32
#2Shuxia Li (University of Southern Denmark)H-Index: 10
Last.Lena Christiansen (University of Southern Denmark)H-Index: 39
view all 8 authors...
Preterm birth is a leading cause of perinatal mortality and long-term health consequences. Epigenetic mechanisms may have been at play in preterm birth survivors, and these could be persistent and detrimental to health later in life. We performed a genome-wide DNA methylation profiling in adult twins of premature birth to identify genomic regions under differential epigenetic regulation in 144 twins with a median age of 33 years (age range 30–36). Association analysis detected three genomic regi...
Source
#1Afsaneh Mohammadnejad (University of Southern Denmark)H-Index: 1
#2Shuxia LiH-Index: 10
Last.Qihua Tan (University of Southern Denmark)H-Index: 32
view all 7 authors...
Electroacupuncture (EA) has been extensively considered as a tool for treating diseases and relieving various pains. However, understanding the molecular mechanisms underlying its effect is of high importance. In this study, we performed a weighted gene co-expression network analysis (WGCNA) on data collected from a microarray experiment to investigate the relationship underlying EA within three factors, time, frequency and tissue regions (periaqueductal gray (PAG) and spinal dorsal horn (DH)) a...
Source
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