Helen R. Murphy
King's College London
EndocrinologyPregnancyType 1 diabetesDiabetes mellitusMedicine
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Publications 130
#1Claire L. MeekH-Index: 7
#2B. Devoy (University of Cambridge)
Last. C. E. Aiken (University of Cambridge)
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AIMS: To determine whether the neonatal and delivery outcomes of gestational diabetes vary seasonally in the context of a relatively cool temperate climate. METHODS: A retrospect cohort of 23 735 women consecutively delivering singleton, live-born term infants in a single tertiary obstetrics centre in the UK (2004-2008) was identified. A total of 985 (4.1%) met the diagnostic criteria for gestational diabetes. Additive dynamic regression models, adjusted for maternal age, BMI, parity and ethnici...
#1Conor Farrington (University of Cambridge)H-Index: 8
#2Roman Hovorka (University of Cambridge)H-Index: 49
Last. Helen R. Murphy (University of Cambridge)H-Index: 27
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BACKGROUND: Clinicians mediate access to closed-loop technology for people with diabetes. Consequently their attitudes regarding appropriate levels of closed-loop usage will play a key role in futu...
#1Conor Farrington (University of Cambridge)H-Index: 8
#2Helen R. Murphy (UEA: University of East Anglia)H-Index: 27
Last. Roman Hovorka (Medical Research Council)H-Index: 49
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#1S. L. Neoh (Northern Health)H-Index: 1
#2Jennifer M. Yamamoto (U of C: University of Calgary)H-Index: 5
Last. Helen R. Murphy (UEA: University of East Anglia)H-Index: 27
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Insulin pump therapy offers theoretical advantages over multiple daily injections (MDI) for fine-tuning insulin dose adjustment. However, evidence regarding the effectiveness of pump compared with MDI on glycemic control during pregnancy is conflicting. The Continuous Glucose Monitoring in Women With Type 1 Diabetes in Pregnancy Trial (CONCEPTT) was a randomized trial of continuous glucose monitoring (CGM) before and during pregnancy (1). A secondary analysis found that pregnant women using pump...
#1Andrea Lake (UEA: University of East Anglia)H-Index: 1
#2Antony Arthur (UEA: University of East Anglia)H-Index: 28
Last. Helen R. Murphy (UEA: University of East Anglia)H-Index: 27
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Aims: To assess the health-related outcomes of hypoglycaemia for people with diabetes admitted to hospital; specifically, hospital length of stay and mortality. Methods: We conducted a systematic review and meta-analysis of studies relating to inpatient hypoglycaemia (<4 mmol/L) for hospitalised adults (≥16 years) with diabetes reporting the primary outcomes of interest, hospital length of stay or mortality. Final papers for inclusion were reviewed in duplicate and the adjusted results of each w...
1 CitationsSource
#1Philippa Prentice (University of Cambridge)H-Index: 11
#2Laurentya Olga (University of Cambridge)H-Index: 1
Last. David B. Dunger (University of Cambridge)H-Index: 97
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Aims/hypothesis This study aimed to explore the infancy growth trajectories of ‘recent’ and ‘earlier’ offspring of mothers with gestational diabetes mellitus (OGDM), each compared with the same control infants, and investigate whether ‘recent’ OGDM still exhibit a classical phenotype, with macrosomia and increased adiposity.
1 CitationsSource
#1Jennifer M. Yamamoto (U of C: University of Calgary)H-Index: 5
#2Jamie L. Benham (U of C: University of Calgary)H-Index: 2
Last. Lois E. Donovan (U of C: University of Calgary)H-Index: 13
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Aims/hypothesis We performed a systematic review and meta-analysis to determine whether exposure to maternal pre-existing diabetes in pregnancy is associated with neurocognitive or behavioural outcomes in offspring.
#1Tadej Battelino (University of Ljubljana)H-Index: 38
#2DanneThomasH-Index: 40
Last. Moshe Phillip (TAU: Tel Aviv University)H-Index: 55
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Improvements in sensor accuracy, greater convenience and ease of use, and expanding reimbursement have led to growing adoption of continuous glucose monitoring (CGM). However, successful utilization of CGM technology in routine clinical practice remains relatively low. This may be due in part to the lack of clear and agreed-upon glycemic targets that both diabetes teams and people with diabetes can work toward. Although unified recommendations for use of key CGM metrics have been established in ...
10 CitationsSource
#1Jennifer M. Yamamoto (U of C: University of Calgary)H-Index: 5
#2R. Corcoy (Ciber)H-Index: 13
Last. Helen R. Murphy (UEA: University of East Anglia)H-Index: 27
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Aims: To examine the relationship between maternal glycaemic control and risk of neonatal hypoglycaemia using conventional and continuous glucose monitoring (CGM) metrics in the Continuous Glucose Monitoring in Type 1 Diabetes Pregnancy Trial (CONCEPTT) participants. Methods: A secondary analysis of CONCEPTT involving 225 pregnant women and their liveborn infants. Antenatal glycaemia was assessed at 12, 24 and 34 weeks gestation. Intrapartum glycaemia was assessed by CGM measures 24 hours prior ...
2 CitationsSource
#1Helen R. Murphy (UEA: University of East Anglia)H-Index: 27
#2Denice S. Feig (U of T: University of Toronto)H-Index: 26
Last. A. Sale
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AIM: To investigate potential cost savings associated with the use of real-time continuous glucose monitoring (RT-CGM) throughout pregnancy in women with type 1 diabetes. METHODS: A budget impact model was developed to estimate, from the perspective of National Health Service England, the total costs of managing pregnancy and delivery in women with type 1 diabetes using self-monitoring of blood glucose (SMBG) with and without RT-CGM. It was assumed that the entire modelled cohort (n=1441) would ...