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Joan Pontius
Saint Petersburg State University
15Publications
11H-index
1,351Citations
Publications 15
Newest
Published on Dec 1, 2014in GigaScience 7.27
Gaik Tamazian6
Estimated H-index: 6
(Saint Petersburg State University),
Serguei Simonov2
Estimated H-index: 2
(Saint Petersburg State University)
+ 22 AuthorsAnton Svitin3
Estimated H-index: 3
(Saint Petersburg State University)
Background Domestic cats enjoy an extensive veterinary medical surveillance which has described nearly 250 genetic diseases analogous to human disorders. Feline infectious agents offer powerful natural models of deadly human diseases, which include feline immunodeficiency virus, feline sarcoma virus and feline leukemia virus. A rich veterinary literature of feline disease pathogenesis and the demonstration of a highly conserved ancestral mammal genome organization make the cat genome annotation ...
18 Citations Source Cite
Published on Jan 1, 2014in Cytogenetic and Genome Research 1.59
Felipe Avila5
Estimated H-index: 5
,
Malorie P. Baily2
Estimated H-index: 2
+ 7 AuthorsTerje Raudsepp35
Estimated H-index: 35
Genome analysis of the alpaca (Lama pacos, LPA) has progressed slowly compared to other domestic species. Here, we report the development of the first comprehensive whole-genome integrated cytogenetic map for the alpaca using fluorescence in situ hybridization (FISH) and CHORI-246 BAC library clones. The map is comprised of 230 linearly ordered markers distributed among all 36 alpaca autosomes and the sex chromosomes. For the first time, markers were assigned to LPA14, 21, 22, 28, and 36. Additi...
11 Citations Source Cite
Published on Sep 21, 2012in Science 41.06
Christopher B. Kaelin13
Estimated H-index: 13
(Stanford University),
Xiao Xu5
Estimated H-index: 5
(Sichuan University)
+ 20 AuthorsGregory M. Cooper35
Estimated H-index: 35
Although long-studied, the underlying basis of mammalian coat patterns remains unclear. By studying a large number of cat species and varieties, Kaelin et al. (p. [1536][1]) identified two genes, Taqpep and Edn3 , as critical factors in the development of feline pigment patterns. Mutations in Taqpep are responsible for the blotched tabby pattern in domestic cats and the unusual coat of wild king cheetahs. Gene expression patterns in cat and cheetah skin suggest that Edn3 is a likely regulator of...
60 Citations Source Cite
Published on May 15, 2011in The Journal of Infectious Diseases 5.19
Jennifer L. Troyer24
Estimated H-index: 24
(Science Applications International Corporation),
George W. Nelson42
Estimated H-index: 42
(Science Applications International Corporation)
+ 24 AuthorsSher L. Hendrickson12
Estimated H-index: 12
Background. Host genetic variation influences human immunodeficiency virus (HIV) infection and progression to AIDS. Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study to identify gene associations with rate of AIDS progression. Methods. European American HIV seroconverters (n = 755) were interrogated for single-nucleotide polymorphisms (SNPs) (n = 700,022) associated with progression to AIDS 1987 (Cox proportional hazards ...
42 Citations Source Cite
Published on Mar 17, 2011in PLOS Genetics 5.54
Polina L. Perelman18
Estimated H-index: 18
,
Warren E. Johnson44
Estimated H-index: 44
+ 11 AuthorsY. Rumpler20
Estimated H-index: 20
Comparative genomic analyses of primates offer considerable potential to define and understand the processes that mold, shape, and transform the human genome. However, primate taxonomy is both complex and controversial, with marginal unifying consensus of the evolutionary hierarchy of extant primate species. Here we provide new genomic sequence (,8 Mb) from 186 primates representing 61 (,90%) of the described genera, and we include outgroup species from Dermoptera, Scandentia, and Lagomorpha. Th...
695 Citations Source Cite
Published on Jan 1, 2011in PLOS ONE 2.77
Polina L. Perelman18
Estimated H-index: 18
,
Warren E. Johnson44
Estimated H-index: 44
+ 11 AuthorsY. Rumpler20
Estimated H-index: 20
7 Citations
Published on Nov 1, 2009in Genome Research 10.10
Harris A. Lewin48
Estimated H-index: 48
,
Denis M. Larkin24
Estimated H-index: 24
+ 1 AuthorsSusan O’Brien171
Estimated H-index: 171
High-resolution physical maps of vertebrate species’ chromosomes empower comparative genomics discovery and are indispensable for sequence assembly precision. Beginning in 2003, the NIH–NHGRI launched an initiative that designated 24 species of mammals for low-coverage whole-genome sequencing in order to provide evolutionary context to human genome annotation (Green 2007) (http://www.genome.gov/25521745). Four principal goals were anticipated for the bold sequencing initiative: (1) to discover e...
111 Citations Source Cite
Published on Jul 1, 2009in Journal of Heredity 2.57
Joan Pontius11
Estimated H-index: 11
,
Stephen J. O’Brien144
Estimated H-index: 144
(National Institutes of Health),
Susan O’Brien171
Estimated H-index: 171
(National Institutes of Health)
Two percentage of the cat genome is a repetitive, feline-specific satellite sequence (FA-SAT) of 483 bp and 65% guaninecytosine content. Previous chromosomal localization of the satellite has demonstrated the satellite’s presence on several discrete regions of the telomeres of chromosomes, predominately on the D, E, and F chromosome groups. The recent assembly of the 1.9� whole-genome shotgun (WGS) sequence of cat illustrates the challenge of the assembly of these large numbers of relatively sho...
3 Citations Source Cite
Published on Apr 1, 2009in Genomics 2.91
Marilyn Menotti-Raymond32
Estimated H-index: 32
,
Victor A. David25
Estimated H-index: 25
+ 7 AuthorsStephen J. O’Brien144
Estimated H-index: 144
Abstract We report on the completion of an autosomal genetic linkage (GL) map of the domestic cat ( Felis silvestris catus ). Unlike two previous linkage maps of the cat constructed with a hybrid pedigree between the domestic cat and the Asian leopard cat, this map was generated entirely with domestic cats, using a large multi-generational pedigree ( n = 256) maintained by the Nestle Purina PetCare Company. Four hundred eighty-three simple tandem repeat (STR) loci have been assigned to linkage g...
32 Citations Source Cite
12