Icons / Logo / Facebook Created with Sketch. Icons / Logo / Google Created with Sketch. Icons / Logo / ORCID Created with Sketch. Branding/Logomark minus Citation Combined Shape Icon/Bookmark-empty Icon/Copy Icon/Collection Icon/Close Copy 7 no author result Created with Sketch. Icon/Back Created with Sketch. Match!
Joseph D. Ng
University of Alabama in Huntsville
73Publications
13H-index
782Citations
Publications 73
Newest
Published on Nov 22, 2017
Noriko Inoguchi1
Estimated H-index: 1
,
Leighton Coates22
Estimated H-index: 22
+ 5 AuthorsJoseph D. Ng13
Estimated H-index: 13
Marc L. Pusey26
Estimated H-index: 26
,
Jorge Barcena1
Estimated H-index: 1
+ 3 AuthorsJoseph D. Ng13
Estimated H-index: 13
Fluorescence can be a powerful tool to aid in the crystallization of proteins. In the trace-labeling approach, the protein is covalently derivatized with a high-quantum-yield visible-wavelength fluorescent probe. The final probe concentration typically labels ≤0.20% of the protein molecules, which has been shown to not affect the crystal nucleation or diffraction quality. The labeled protein is then used in a plate-screening experiment in the usual manner. As the most densely packed state of the...
Joseph D. Ng13
Estimated H-index: 13
(UAH: University of Alabama in Huntsville),
James K. Baird14
Estimated H-index: 14
(UAH: University of Alabama in Huntsville)
+ 3 AuthorsSijay Huang1
Estimated H-index: 1
(UAH: University of Alabama in Huntsville)
Neutron macromolecular crystallography (NMC) is the prevailing method for the accurate determination of the positions of H atoms in macromolecules. As neutron sources are becoming more available to general users, finding means to optimize the growth of protein crystals to sizes suitable for NMC is extremely important. Historically, much has been learned about growing crystals for X-ray diffraction. However, owing to new-generation synchrotron X-ray facilities and sensitive detectors, protein cry...
Published on Jan 1, 2015in Biophysical Journal 3.67
Debsindhu Bhowmik9
Estimated H-index: 9
(WSU: Wayne State University),
Gurpreet K. Dhindsa3
Estimated H-index: 3
(WSU: Wayne State University)
+ 6 AuthorsXiang Qiang Chu13
Estimated H-index: 13
(WSU: Wayne State University)
Life is traditionally seen as being driven by energy from the sun, however deep sea organisms have no access to sunlight, so they depend on nutrients found in the dusty chemical deposits and hydrothermal fluids around the hydrothermal vent zones, where they live. In this study, we use neutron spin-echo spectroscopy (NSE) to measure the inter-domain motions of the inorganic pyrophosphatase (IPPase) enzyme derived from thermostable microorganisms. IPPase is of extreme interest for biophysical stud...
Published on Aug 5, 2014in Acta Crystallographica Section A 1.88
Joseph D. Ng13
Estimated H-index: 13
,
Ronny C. Hughes5
Estimated H-index: 5
+ 5 AuthorsAndreas Ostermann18
Estimated H-index: 18
Published on Aug 5, 2014in Acta Crystallographica Section A 1.88
Marc L. Pusey7
Estimated H-index: 7
,
Michelle Morris1
Estimated H-index: 1
+ 2 AuthorsJoseph D. Ng13
Estimated H-index: 13
Published on Aug 1, 2014in Journal of Applied Crystallography
Leighton Coates22
Estimated H-index: 22
,
Stephen J. Tomanicek10
Estimated H-index: 10
+ 4 AuthorsAndreas Ostermann18
Estimated H-index: 18
The use of cryocooling in neutron diffraction has been hampered by several technical challenges such as the need for specialized equipment and techniques. Recently we have developed and deployed equipment and strategies that allow for routine neutron data collection on cryocooled crystals using off the shelf components. This system has several advantages, compared to a closed displex cooling system such as fast cooling coupled with easier crystal mounting and centering. The ability to routinely ...
12345678