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José Jacobs
Utrecht University
33Publications
12H-index
560Citations
Publications 33
Newest
#1Kati Huttunen (Cardiff University)H-Index: 17
#2Anna Julia Wlodarczyk (Cardiff University)H-Index: 5
Last.Kelly Ann Berube (Cardiff University)H-Index: 29
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Exposure to moisture-damaged indoor environments is associated with adverse respiratory health effects, but responsible factors remain unidentified. In order to explore possible mechanisms behind these effects, the oxidative capacity and hemolytic activity of settled dust samples (n = 25) collected from moisture-damaged and non-damaged schools in Spain, the Netherlands, and Finland were evaluated and matched against the microbial content of the sample. Oxidative capacity was determined with plas...
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#1Lidia CasasH-Index: 10
#2Ana EspinosaH-Index: 11
Last.Jan-Paul ZockH-Index: 35
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Objectives: We investigated the effect of weekends and school holidays on the daily frequency and severity of respiratory and other symptoms among children attending schools with (index) or without (reference) moisture damage in Spain, the Netherlands and Finland. Methods: Throughout one year, parents of 419 children with a respiratory condition attending index (n=15) or reference (n=10) primary schools completed three symptom diaries. We assessed associations between lower respiratory tract, up...
6 CitationsSource
#1Lidia CasasH-Index: 10
#2Ana EspinosaH-Index: 11
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#1Alejandro Dorado-García (UU: Utrecht University)H-Index: 7
#2Dik Mevius (UU: Utrecht University)H-Index: 41
Last.Dick Heederik (UU: Utrecht University)H-Index: 74
view all 7 authors...
Objectives To quantify associations between antimicrobial use and acquired resistance in indicator Escherichia coli over a period of time which involved sector-wide antimicrobial use reductions in broilers and pigs (years 2004–14), veal calves (2007–14) and dairy cattle (2005–14). Prevalence estimates of resistance were predicted for a hypothetical further decrease in antimicrobial use. Methods Data reported annually for the resistance surveillance programme in the Netherlands were retrieved. Tw...
33 CitationsSource
#1José JacobsH-Index: 12
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Introduction: Dampness and mould exposure have been linked to respiratory symptoms, but studies on causative agents are limited. We aim to explore whether microbial secondary metabolites explain as...
#1Dick Heederik (UU: Utrecht University)H-Index: 74
#2José Jacobs (UU: Utrecht University)H-Index: 12
Last.Remko Houba (UU: Utrecht University)H-Index: 13
view all 6 authors...
Background Chloroplatinate salts are well-known respiratory sensitizing agents leading to work-related sensitization and allergies in the work environment. No quantitative exposure-response relation has been described for chloroplatinate salts. Objective We sought to evaluate the quantitative exposure-response relation between occupational chloroplatinate exposure and sensitization. Methods A retrospective cohort study was conducted using routinely collected health surveillance data and chloropl...
7 CitationsSource
#1Lidia CasasH-Index: 10
#2Aina EspinosaH-Index: 1
Last.Jan-Paul ZockH-Index: 35
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We welcome the opportunity to respond to the concerns of Dr Wise1 from the American Chemistry Council, regarding our report on the association between childhood infections and use of bleach at home.2 Dr Wise expresses disappointment with ‘design flaws’ and ‘the speculative nature of our conclusions’. We do not agree that our study was badly designed, and the limitations have been carefully considered and discussed in our original paper. We relied on questionnaires for both exposure and outcome, ...
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#1Femke J. Taverne (UU: Utrecht University)H-Index: 3
#2José Jacobs (UU: Utrecht University)H-Index: 12
Last.I.M. van Geijlswijk (UU: Utrecht University)H-Index: 3
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Background Antimicrobial use in livestock is one of the factors contributing to selection and spread of resistant microorganisms in the environment. National veterinary antimicrobial consumption monitoring programs are therefore in place in a number of countries in the European Union. However, due to differences in methodology, results on veterinary antimicrobial consumption from these national monitoring programs cannot be compared internationally. International comparison is highly needed to e...
10 CitationsSource
#1Lidia CasasH-Index: 10
#2Ana EspinosaH-Index: 11
Last.Jan-Paul Zock (Ciber)H-Index: 35
view all 11 authors...
Objective To report the effects of bleach use at home on the frequency of infections in 9102 school-age children participating in the HITEA project. Methods Parents of pupils aged 6–12 years from schools in Barcelona province (Spain), Utrecht province (the Netherlands) and Eastern and Central Finland were administered a questionnaire including questions on the frequency of infections (influenza, tonsillitis, sinusitis, otitis, bronchitis and pneumonia) in the past 12 months and bleach use at hom...
8 CitationsSource
#1José Jacobs (UU: Utrecht University)H-Index: 12
#2Alícia Borràs-Santos (Ciber)H-Index: 9
Last.Dick Heederik (UU: Utrecht University)H-Index: 74
view all 11 authors...
Background Respiratory health effects of damp housing are well recognised, but less is known about the effect of dampness and water damage in schools. The HITEA study previously reported a higher prevalence of respiratory symptoms in pupils from moisture damaged schools, but the role of specific microbial exposures remained unclear. Objectives To study associations between school dampness, levels of fungal and bacterial markers, respiratory symptoms and lung function in children. Methods Primary...
32 CitationsSource
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