Asim Shabbir
National University of Singapore
CancerSurgeryDiabetes mellitusGeneral surgeryMedicine
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Publications 157
#1Hon Lyn TanH-Index: 2
#2Guowei KimH-Index: 7
Last. Boon Cher GohH-Index: 31
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#1Muhammad Nadzim Bin Ramli (Genome Institute of Singapore)
#2Yee Siang Lim (Genome Institute of Singapore)
Last. Einsi Lynn Soe (Genome Institute of Singapore)
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Abstract: Background & Aims There are few in vitro models for studying the 3-dimensional interactions among different liver cell types during organogenesis or disease development. We aimed to generate hepatic organoids that comprise different parenchymal liver cell types and have structural features of the liver, using human pluripotent stem cells. Methods We cultured H1 human embryonic stem cells (WA-01, passage 27-40) and induced pluripotent stem cells (GM23338) with a series of chemically def...
#1Chia Rou Yeo (NUS: National University of Singapore)H-Index: 3
#2Madhur Agrawal (NUS: National University of Singapore)H-Index: 6
Last. E. Shyong Tai (NUS: National University of Singapore)H-Index: 63
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#1Koh Zong JieH-Index: 1
Last. Asim Shabbir (NUS: National University of Singapore)H-Index: 21
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Abstract Setting Primary bariatric surgery has been well established to be effective in inducing improvement of diabetes and other associated co-morbidities in patients with obesity. Evidence demonstrating the influence of revisional bariatric surgery on this trajectory, however, is lacking. Objectives We performed a systematic review and meta-analysis to examine the impact of revisional bariatric surgery on obesity-related metabolic outcomes. Methods We examined outcomes of remission and improv...
2 CitationsSource
#2Jun Liang TehH-Index: 3
Last. Jimmy SoH-Index: 39
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#1Asim ShabbirH-Index: 21
#2Raj K. MenonH-Index: 1
Last. Davide Lomanto (NUS: National University of Singapore)H-Index: 16
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The COVID-19 pandemic has resulted in significant changes to surgical practice across the worlds. Some countries are seeing a tailing down of cases, while others are still having persistent and sustained community spread. These evolving disease patterns call for a customized and dynamic approach to the selection, screening, planning, and for the conduct of surgery for these patients. The current literature and various international society guidelines were reviewed and a set of recommendations we...
1 CitationsSource
#1Daryl Kai Ann ChiaH-Index: 2
Last. Jimmy SoH-Index: 39
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#1Vinay Panday (University Health System)
#2Asim ShabbirH-Index: 21
Last. Kian Keong Poh (University Health System)H-Index: 2
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INTRODUCTION: Bariatric surgery is considered an effective treatment for weight loss and improving the metabolic profile of obese patients. Obesity-related comorbidities such as hyperlipidaemia and type 2 diabetes mellitus (DM) are significant cardiovascular risk factors. Additionally, statins have increased the onset of DM in prospective clinical trials, and many obese patients are on statins. We retrospectively examined the effect of bariatric surgery on lipid profile, DM control and weight lo...
#1Jun Liang Teh (University Health System)H-Index: 2
#2Wei Qi Leong (University Health System)
Last. Asim Shabbir (University Health System)H-Index: 21
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Abstract Background The effect of bariatric surgery on improvement and remission of type 2 diabetes mellitus (T2D) is well studied. The effect of surgery on glycemic profiles of obese, but non diabetic individuals is unknown. Objectives We aim to study changes in glycemic indices in obese non-diabetics undergoing bariatric surgery and correlate fat mass loss with changes in glycemic profiles. Setting University Hospital, Singapore Methods A prospective database of non T2D patients who underwent ...