Sonia S. Anand
Population Health Research Institute
CardiologyDiseasePopulationDiabetes mellitusMedicine
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Publications 448
#1A. Lamri (McMaster University)H-Index: 4
#2Shihong Mao (Population Health Research Institute)H-Index: 2
Last. Sonia S. Anand (McMaster University)H-Index: 76
view all 6 authors...
Gestational diabetes Mellitus (GDM) affects 1 in 7 births and is associated with numerous adverse health outcomes for both mother and child. GDM is suspected to share a large common genetic background with type 2 diabetes (T2D). The aim of our study was to characterize different GDM polygenic risk scores (PRSs) and test their association with GDM using data from the South Asian Birth Cohort (START). PRSs were derived for 832 South Asian women from START using the pruning and thresholding (P + T)...
#1Marjan Walli-Attaei (Population Health Research Institute)
#2Philip Joseph (Population Health Research Institute)H-Index: 17
Last. Fernando Lanas (UFRO: University of La Frontera)H-Index: 37
view all 35 authors...
Summary Background Some studies, mainly from high-income countries (HICs), report that women receive less care (investigations and treatments) for cardiovascular disease than do men and might have a higher risk of death. However, very few studies systematically report risk factors, use of primary or secondary prevention medications, incidence of cardiovascular disease, or death in populations drawn from the community. Given that most cardiovascular disease occurs in low-income and middle-income ...
1 CitationsSource
#1Russell J. de Souza (McMaster University)H-Index: 34
#2Mahshid Dehghan (Population Health Research Institute)H-Index: 24
Last. Rafael DiazH-Index: 9
view all 28 authors...
BACKGROUND: The association of nuts with cardiovascular disease and deaths has been investigated mostly in Europe, the USA, and East Asia, with few data available from other regions of the world or from low- and middle-income countries. OBJECTIVE: To assess the association of nuts with mortality and cardiovascular disease (CVD). METHODS: The Prospective Urban Rural Epidemiology study is a large multinational prospective cohort study of adults aged 35-70 y from 16 low-, middle-, and high-income c...
#1Jan SteffelH-Index: 29
#2John W. EikelboomH-Index: 93
Last. Keith A.A. FoxH-Index: 123
view all 6 authors...
Background: Rivaroxaban 2.5mg twice daily plus aspirin 100mg reduced the risk of cardiovascular events as compared to aspirin monotherapy in the COMPASS (Cardiovascular Outcomes for People Using An...
#1Yan Liang (Peking Union Medical College)H-Index: 5
#2Jun Zhu (Peking Union Medical College)H-Index: 35
Last. Keith A.A. Fox (Edin.: University of Edinburgh)H-Index: 123
view all 17 authors...
AIMS: The COMPASS trial demonstrated that the combination of rivaroxaban 2.5mg twice-daily and aspirin 100mg once daily compared with aspirin 100 mg once daily reduced major adverse cardiovascular events (MACE) in patients with chronic coronary artery disease (CAD) or peripheral artery disease (PAD) by 24% during a mean follow-up of 23 months. We explored whether this effect varies by sex. METHODS AND RESULTS: The effects were examined in women and men using log-rank tests and Kaplan-Meier curve...
#1Mahshid Dehghan (Population Health Research Institute)H-Index: 24
#2Andrew Mente (McMaster University)H-Index: 32
Last. Patricio López-JaramilloH-Index: 47
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BACKGROUND: Eggs are a rich source of essential nutrients, but they are also a source of dietary cholesterol. Therefore, some guidelines recommend limiting egg consumption. However, there is contradictory evidence on the impact of eggs on diseases, largely based on studies conducted in high-income countries. OBJECTIVES: Our aim was to assess the association of egg consumption with blood lipids, cardiovascular disease (CVD), and mortality in large global studies involving populations from low-, m...
2 CitationsSource
#1Balaji Bhavadharini (Population Health Research Institute)
#2Mahshid Dehghan (Population Health Research Institute)H-Index: 24
Last. Edelweiss Wentzel-Viljoen (NWU: North-West University)H-Index: 14
view all 40 authors...
Objective Our aims were to assess the association of dairy intake with prevalence of metabolic syndrome (MetS) (cross-sectionally) and with incident hypertension and incident diabetes (prospectively) in a large multinational cohort study. Methods The Prospective Urban Rural Epidemiology (PURE) study is a prospective epidemiological study of individuals aged 35 and 70 years from 21 countries on five continents, with a median follow-up of 9.1 years. In the cross-sectional analyses, we assessed the...
#1Sandi Azab (McMaster University)H-Index: 1
#2Russell J. de Souza (McMaster University)H-Index: 34
Last. Philip Britz-McKibbin (McMaster University)H-Index: 26
view all 9 authors...
Nutritional studies rely on various biological specimens for fatty acid (FA) determination, yet it is unclear how levels of serum non-esterified FA (NEFAs) correlate with other circulating lipid pools. Here, we used a high throughput method (< 4 min/sample) based on multisegment injection-non-aqueous-capillary electrophoresis-mass spectrometry (MSI-NACE-MS) to investigate whether specific serum NEFAs have utility as biomarkers of dietary fat intake in women. We first identified circulating NEFAs...
2 CitationsSource
BACKGROUND: Patients with peripheral artery disease who have undergone lower-extremity revascularization are at high risk for major adverse limb and cardiovascular events. The efficacy and safety of rivaroxaban in this context are uncertain. METHODS: In a double-blind trial, patients with peripheral artery disease who had undergone revascularization were randomly assigned to receive rivaroxaban (2.5 mg twice daily) plus aspirin or placebo plus aspirin. The primary efficacy outcome was a composit...
8 CitationsSource
#1Deepak L. Bhatt (Brigham and Women's Hospital)H-Index: 122
#2John W. Eikelboom (Population Health Research Institute)H-Index: 93
Last. Olga Shestakovska (Population Health Research Institute)H-Index: 13
view all 20 authors...
Background: Patients with established coronary artery disease (CAD) or peripheral artery disease (PAD) often have diabetes mellitus. These patients are at high risk of future vascular events. Metho...
3 CitationsSource