Sonia S. Anand
Population Health Research Institute
Publications 414
#1Thomas Vanassche (Katholieke Universiteit Leuven)H-Index: 15
#2Peter Verhamme (Katholieke Universiteit Leuven)H-Index: 34
Last.Aldo P. MaggioniH-Index: 98
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AimsSecondary prevention in patients with coronary artery disease and peripheral artery disease involves antithrombotic therapy and optimal control of cardiovascular risk factors. In the Cardiovasc...
Purpose of Review Peripheral artery disease (PAD) affects an estimated 200 million people worldwide and is associated with significant cardiovascular morbidity and mortality. Cardiovascular risk is further increased among individuals with polyvascular disease, where either cerebrovascular or coronary artery disease is present in addition to PAD. In this review, we present common clinical scenarios encountered when managing patients with PAD and provide an evidence-based approach to prescribing o...
#1Sonia S. Anand (McMaster University)H-Index: 74
#2Jack V. Tu (U of T: University of Toronto)H-Index: 78
Last.Paul Poirier (Laval University)H-Index: 53
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#1John W. Eikelboom (Population Health Research Institute)H-Index: 89
#2Stuart J. Connolly (Population Health Research Institute)H-Index: 53
Last.Deepak L. Bhatt (Brigham and Women's Hospital)H-Index: 119
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Background: Patients treated with antithrombotic drugs are at risk of bleeding. Bleeding may be the first manifestation of underlying cancer. Methods: We examined new cancers diagnosed in relation ...
#1Russell J. de Souza (McMaster University)H-Index: 35
#2Mahshid Dehghan (Population Health Research Institute)H-Index: 22
Last.Sonia S. Anand (McMaster University)H-Index: 74
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#1Paul Moayyedi (Population Health Research Institute)H-Index: 2
#2John A. Eikelboom (Population Health Research Institute)
Last.Kelley Branch (University of Washington Medical Center)H-Index: 1
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Abstract Background & Aims Proton pump inhibitors (PPIs) are effective at treating acid-related disorders. These drugs are well tolerated in the short term, but long-term treatment was associated with adverse events in observational studies. We aimed to confirm these findings in an adequately powered randomized trial. Methods We performed a 3x2 partial factorial double-blind trial of 17,598 participants with stable cardiovascular disease and peripheral artery disease randomly assigned to groups ...
#1Paul MoayyediH-Index: 81
#2Paul Moayyedi (Population Health Research Institute)H-Index: 2
Last.Sonia S. AnandH-Index: 74
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Background & Aims Antiplatelets and anticoagulants are associated with increased upper gastrointestinal bleeding. We evaluated whether proton pump inhibitor therapy could reduce this risk. Methods We performed a 3 × 2 partial factorial double-blind trial of 17,598 participants with stable cardiovascular disease and peripheral artery disease. Participants were randomly assigned to groups given pantoprazole 40 mg daily or placebo, as well as rivaroxaban 2.5 mg twice daily with aspirin 100 mg once ...