Tianzi Jiang
Chinese Academy of Sciences
PsychologyNeuroscienceFunctional magnetic resonance imagingPrefrontal cortexResting state fMRI
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Publications 524
#1Jiaojiao Hua (CAS: Chinese Academy of Sciences)
#2Zhengyi Yang (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Shan Yu (CAS: Chinese Academy of Sciences)H-Index: 11
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Orchestrated expressions of tens of thousands of genes give rise to the complexity of the brain. However, it is unclear what is the structure governing these myriads of gene-gene interactions. By analyzing the transcription data obtained from more than 3000 sites in human brains, we found that pair-wise interactions between genes are sufficient to accurately predict both the transcription pattern of the whole genome for individual brain areas and the transcription profile of the entire brain, su...
#1Junjie Zhuo (UQ: University of Queensland)
#2Yuanchao Zhang (University of Electronic Science and Technology of China)H-Index: 13
Last. Tianzi Jiang (CAS: Chinese Academy of Sciences)H-Index: 67
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The failure of all anti-amyloid-β (Aβ) drugs has led to a debate about the central role of amyloid in sporadic Alzheimer9s disease (SAD). In order to resolve this issue, it is necessary to evaluate the impact of Aβ biomarkers on SAD by measuring the dynamic changes in biomarkers and clinical profiles in the progression of SAD. We identified a clearer picture of the clinical and biomarker changes in the progression of SAD by aligning the clinical diagnosis of mild cognitive impairment (MCI) or AD...
#1Dan Jin (CAS: Chinese Academy of Sciences)H-Index: 1
#2Pan Wang (TJU: Tianjin University)
Last. Hongxiang Yao (Chinese PLA General Hospital)H-Index: 9
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Alzheimer's disease (AD) is associated with disruptions in brain activity and networks. However, there is substantial inconsistency among studies that have investigated functional brain alterations in AD; such contradictions have hindered efforts to elucidate the core disease mechanisms. In this study, we aim to comprehensively characterize AD-associated functional brain alterations using one of the world's largest resting-state functional MRI (fMRI) biobank for the disorder. The biobank include...
#1Jianlong Zhao (CAS: Chinese Academy of Sciences)H-Index: 21
#2Jinjie Huang (Harbin University of Science and Technology)
Last. Vince D. Calhoun (Georgia Institute of Technology)H-Index: 93
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Abstract As a popular deep learning method, generative adversarial networks (GAN) have achieved outstanding performance in multiple classifications and segmentation tasks. However, the application of GANs to fMRI data is relatively rare. In this work, we proposed a functional network connectivity (FNC) based GAN for classifying psychotic disorders from healthy controls (HCs), in which FNC matrices were calculated by correlation of time courses derived from non-artefactual fMRI independent compon...
#1Bin He (CAS: Chinese Academy of Sciences)
#2Zhengyi Yang (CAS: Chinese Academy of Sciences)H-Index: 16
Last. Tianzi JiangH-Index: 67
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Non-human primate models are widely used in studying the brain mechanism underlying brain development, cognitive functions and psychiatric disorders. Neuorimaging techniques, such as magnetic resonance imaging, play an important role in the examinations of brain structure and functions. As an indispensable tool for brain imaging data analysis, brain atlases have been extensively investigated and a variety of versions constructed. These atlases diverge in the criteria based on which they are plot...
#1Ming Song (CAS: Chinese Academy of Sciences)H-Index: 18
#2Yi Yang (Capital Medical University)
Last. Tianzi JiangH-Index: 67
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Disorders of consciousness (DoC) are acquired conditions of severe altered consciousness. During the past decades, some prognostic models for DoC have been explored on the basis of a variety of predictors, including demographics, neurological examinations, clinical diagnosis, neurophysiology and brain images. In this article, a systematic review of pertinent literature was conducted. We identified and evaluated 21 prognostic models involving a total of 1201 DoC patients. In terms of the reported...
#1Kun Zhao (CAS: Chinese Academy of Sciences)H-Index: 27
#2Yanhui Ding (SDNU: Shandong Normal University)H-Index: 1
Last. Chengyuan Song (SDU: Shandong University)
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Abstract Hippocampal morphological change is one of the main hallmarks of Alzheimer's disease (AD). However, whether hippocampal radiomic features are robust as predictors of progression from mild cognitive impairment (MCI) to AD dementia and whether these features provide any neurobiological foundation remains unclear. The primary aim of this study was to verify whether hippocampal radiomic features can serve as robust MRI markers for AD. Multivariate classifier-based SVM analysis provided indi...
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#2Yongfeng YangH-Index: 10
Last. Xueqin SongH-Index: 12
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Objectives: Abnormal activity of the subgenual anterior cingulate cortex (sACC) is implicated in depression, suggesting the sACC as a potentially effective target for therapeutic modulation in cases resistant to conventional treatments (treatment-resistant depression, TRD). We hypothesized that areas in the prefrontal cortex (PFC) with direct fiber connections to the sACC may be particularly effective sites for treatment using transcranial magnetic stimulation (TMS). The aim of this study was to...
#1Ang Li (CAS: Chinese Academy of Sciences)H-Index: 2
#2Andrew Zalesky (University of Melbourne)H-Index: 42
Last. Guangxiang Rao (CAS: Chinese Academy of Sciences)
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Mounting evidence suggests that function and connectivity of the striatum is disrupted in schizophrenia1–5. We have developed a new hypothesis-driven neuroimaging biomarker for schizophrenia identification, prognosis and subtyping based on functional striatal abnormalities (FSA). FSA scores provide a personalized index of striatal dysfunction, ranging from normal to highly pathological. Using inter-site cross-validation on functional magnetic resonance images acquired from seven independent scan...
#1Dongya Wu (CAS: Chinese Academy of Sciences)H-Index: 1
#2Xin Li (ZJU: Zhejiang University)H-Index: 1
Last. Tianzi JiangH-Index: 67
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Different patterns of brain activity are observed in various subjects across a wide functional domain. However, these individual differences, which are often neglected through the group average, are not yet completely understood. Based on the fundamental assumption that human behavior is rooted in the underlying brain function, we speculated that the individual differences in brain activity are reflected in the individual differences in behavior. Adopting 98 behavioral measures and assessing the...