Asahiro Morishita
Kagawa University
Publications 108
#1Koji FujitaH-Index: 9
#2Takako NomuraH-Index: 11
Last.Tsutomu MasakiH-Index: 34
view all 0 authors...
Albumin–bilirubin (ALBI) grade is defined using the ALBI score, which is calculated based on total serum bilirubin and albumin. This study aimed to evaluate the diagnostic ability of the ALBI score for determining hepatic fibrosis stage and transplant-free survival in primary biliary cholangitis (PBC) patients. A total of 181 Japanese patients with biopsy-proven or serologically diagnosed PBC were enrolled. The pathological stage was assessed using the Scheuer classification. The ALBI score diff...
Esophageal squamous cell carcinoma (ESCC) is the most common primary esophageal malignancy. Telmisartan, an angiotensin II type 1 (AT1) receptor blocker (ARB) and a widely used antihypertensive, has been shown to inhibit proliferation of various cancer types. This study evaluated the effects of telmisartan on human ESCC cell proliferation in vitro and in vivo and sought to identify the microRNAs (miRNAs) involved in these antitumor effects. We examined the effects of telmisartan on three human E...
#1Lei Li (Kagawa University)H-Index: 2
#2Yu Guan (Kagawa University)H-Index: 2
Last.Akira Nishiyama (Kagawa University)H-Index: 2
view all 8 authors...
Herein, we studied the effects of the novel nonsteroidal selective mineralocorticoid receptor (MR) blocker, esaxerenone, on blood pressure and renal injury in Dahl salt-sensitive (DSS) rats. We also monitored intact urinary and total angiotensinogen (AGT). DSS rats were given a normal salt diet (NS: 0.4% NaCl, n = 10), a high-salt diet (HS: 8% NaCl, n = 10), HS + esaxerenone (1 mg/kg/day, p.o., n = 10), or HS + losartan (angiotensin II receptor blocker, 10 mg/kg/day, p.o., n = 10) for 6 weeks. G...
Galectin-9 (Gal-9) enhances tumor immunity mediated by T cells, macrophages, and dendritic cells. Its expression level in various cancers correlates with prognosis. Furthermore, Gal-9 directly induces apoptosis in various cancers; however, its mechanism of action and bioactivity has not been clarified. We evaluated Gal-9 antitumor effect against esophageal squamous cell carcinoma (ESCC) to analyze the dynamics of apoptosis-related molecules, elucidate its mechanism of action, and identify releva...
#1Kyoko Oura (Kagawa University)H-Index: 4
#2Koji Fujita (Kagawa University)H-Index: 9
Last.Tsutomu Masaki (Kagawa University)H-Index: 34
view all 15 authors...
#1Takashi Himoto (UHSA: University of Health Sciences Antigua)H-Index: 4
#2Eiichiro Hirakawa (UHSA: University of Health Sciences Antigua)H-Index: 3
Last.Tsutomu Masaki (Kagawa University)H-Index: 34
view all 9 authors...