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Thorkild I. A. Sørensen
Novo Nordisk Foundation
Publications 502
Published on Apr 23, 2019in Scientific Reports 4.12
M Mendall4
Estimated H-index: 4
(Croydon University Hospital),
Camilla B. Jensen4
Estimated H-index: 4
(Frederiksberg Hospital)
+ 2 AuthorsTine Jess30
Estimated H-index: 30
(AAU: Aalborg University)
Body mass index (BMI) is associated with increased future risk of inflammatory bowel disease(IBD) particularly Crohn’s disease(CD), where associations with high and low BMI have been observed. Most studies are based on adult women. We aimed to explore the impact of BMI in men entering adult life on their long-term risk of developing IBD. A total of 377,957 men born during 1939–1959, with BMI measured at draft boards at mean age 19, were followed from 1977, or time of examination, to end of 2015....
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Published on Apr 23, 2019in Nature Communications 12.35
Leanne K. Küpers8
Estimated H-index: 8
Claire Monnereau6
Estimated H-index: 6
(EUR: Erasmus University Rotterdam)
+ 124 AuthorsDarina Czamara26
Estimated H-index: 26
(MPG: Max Planck Society)
Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium, we find that DNA methylation in neonatal blood is associated with birthweight at 914 sites, with a difference in birthweight ranging from −183 to 178 grams per 10% increase in methylation (PBonferroni < 1.06 x 10−7). In additi...
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Published on Jun 14, 2019in Obesity 4.04
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Published on May 1, 2019in Nature Genetics 27.13
Nicole M. Warrington31
Estimated H-index: 31
(Translational Research Institute),
Robin N. Beaumont12
Estimated H-index: 12
(RD&E: Royal Devon and Exeter Hospital)
+ 205 AuthorsBjarke Feenstra32
Estimated H-index: 32
Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effect...
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Published on Apr 17, 2019in Obesity Surgery 3.89
Martin Aasbrenn (Innlandet Hospital Trust), Theresia M. Schnurr3
Estimated H-index: 3
(UCPH: University of Copenhagen)
+ 13 AuthorsKristoffer Sølvsten Burgdorf11
Estimated H-index: 11
(Copenhagen University Hospital)
Background The weight loss after bariatric surgery shows considerable individual variation. Twin studies of response to dietary interventions and studies of bariatric surgery patients suggest that genetic differences may play a role. This study aimed to examine the effect of three genetic risk scores on the inter-individual variation in excess body mass index loss (EBMIL) after Roux-en-Y gastric bypass. Furthermore, we searched among known adiposity-related single nucleotide polymorphisms (SNPs)...
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Published on Apr 15, 2019in Obesity Reviews 8.48
Uku Vainik9
Estimated H-index: 9
Alain Dagher59
Estimated H-index: 59
+ 7 AuthorsRené Mõttus2
Estimated H-index: 2
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Published on Apr 10, 2019in International Journal of Epidemiology 8.36
Sylvain Sebert28
Estimated H-index: 28
(Imperial College London),
Estelle Lowry4
Estimated H-index: 4
(University of Oulu)
+ 40 AuthorsTeija Juola1
Estimated H-index: 1
(University of Oulu)
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