Background Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to compare trends in total, HDL and non-HDL cholesterol and the total-to-HDL cholesterol ratio in Asian and Western countries. Methods We pooled 458 population-based studies with 82.1 million participants in 23 Asian and Western countries. We estimated changes in mean total, HDL and no...
Last.Majid Ezzati(Imperial College London)H-Index: 107
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Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbaniz ...
Objective: To describe growth patterns of weight of Australian Aboriginal children from birth to 21 months living in the Fitzroy Valley in the Kimberley region before and after the introduction of alcohol restrictions in 2007. Methods: Longitudinal weight growth data was examined from three cohorts using mixed model analysis. The cohorts were children participating in the Lililwan Study, born 2002-2003, the Kimberley CommuniCare Cohort, born 2009-2011, and a historical cohort, born 1974-1993. Re...
Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood press...