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Edna Keeney
University of Bristol
ObstetricsIntensive care medicineCost-effectiveness analysisMedicineMeta-analysis
35Publications
6H-index
106Citations
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Publications 36
Newest
#1Howard Thom (UoB: University of Bristol)H-Index: 10
#2Jason Shafrin (Precision Health Economics)H-Index: 7
Last. Nirmish Shah (Duke University)H-Index: 8
view all 9 authors...
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#1Karolis Zienius (Edin.: University of Edinburgh)H-Index: 3
#2Ip Chak-Lam (Edin.: University of Edinburgh)
Last. Paul M. Brennan (Edin.: University of Edinburgh)H-Index: 2
view all 14 authors...
Background Brain tumour patients see their primary care doctor on average three or more times before diagnosis, so there may be an opportunity to identify ‘at risk’ patients earlier. Suspecting a brain tumour diagnosis is difficult because brain tumour-related symptoms are typically non-specific.
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#1Howard Thom (UoB: University of Bristol)H-Index: 10
Last. Serban StoicaH-Index: 18
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Objectives In young and middle-aged adults, there are three current options for aortic valve replacement (AVR), namely mechanical AVR (mechAVR), tissue AVR (biological AVR) and the Ross operation, with no clear guidance on the best option. We aim to compare the clinical effectiveness and cost-effectiveness of the Ross procedure with conventional AVR in young and middle-aged adults. Methods This is a systematic literature review and meta-analysis of AVR options. Markov multistate model was adopte...
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#1Edna Keeney (UoB: University of Bristol)H-Index: 6
#2Dalia Dawoud (Royal College of Physicians)H-Index: 8
Last. Sofia Dias (UoB: University of Bristol)H-Index: 33
view all 3 authors...
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#1Yuji Oba (MU: University of Missouri)H-Index: 10
#2Edna KeeneyH-Index: 6
Last. Sofia Dias (UoB: University of Bristol)H-Index: 33
view all 4 authors...
Background: Long-acting bronchodilators such as long-acting β-agonist (LABA), long-acting muscarinic antagonist (LAMA), and LABA/inhaled corticosteroid (ICS) combinations have been used in people with moderate to severe chronic obstructive pulmonary disease (COPD) to control symptoms such as dyspnoea and cough, and prevent exacerbations. A number of LABA/LAMA combinations are now available for clinical use in COPD. However, it is not clear which group of above mentioned inhalers is most effectiv...
7 CitationsSource
#1Karolis ZieniusH-Index: 3
#2Paul Brennan (Edin.: University of Edinburgh)H-Index: 40
Last. Robin GrantH-Index: 28
view all 9 authors...
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#1Eric SladeH-Index: 2
#2Edna Keeney (UoB: University of Bristol)H-Index: 6
Last. Tim Kendall (Royal College of Psychiatrists)H-Index: 25
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Background Bulimia nervosa (BN) is a severe eating disorder that can be managed using a variety of treatments including pharmacological, psychological, and combination treatments. We aimed to compare their effectiveness and to identify the most effective for the treatment of BN in adults. Methods A search was conducted in Embase, Medline, PsycINFO, and Central from their inception to July 2016. Studies were included if they reported on treatments for adults who fulfilled diagnostic criteria for ...
6 CitationsSource
Source
#1Edna Keeney (UoB: University of Bristol)H-Index: 6
#2Dalia Dawoud (Royal College of Physicians)H-Index: 8
Last. Sofia Dias (UoB: University of Bristol)H-Index: 33
view all 3 authors...
Abstract Background Clinical trials report severe hypoglycaemic events as the number of patients with at least one event out of the total randomised or number of events for a given total exposure. Different network meta-analysis models have been used to analyse these different data types. Objective This aim of this article was to establish the impact of using the different models on effectiveness, costs and health utility estimates. Methods We analysed a dataset used in a recent network meta-ana...
1 CitationsSource
#1Edna Keeney (UoB: University of Bristol)H-Index: 6
#2Sofia Dias (UoB: University of Bristol)H-Index: 33
Last. Dalia Dawoud (Royal College of Physicians)H-Index: 8
view all 3 authors...
ObjectivesPublished clinical trials report severe hypoglycaemic events in different ways. Some report number of patients who suffered at least one event out of total number randomised and others report number of events for a given total exposure. The different data types can be modelled in different ways; therefore, three models have been used in published Bayesian Network Meta Analyses (NMAs) of hypoglycaemic events; models with a binomial likelihood reporting odds ratios (using a logit link) o...
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