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Luca Miele
Sapienza University of Rome
244Publications
28H-index
3,642Citations
Publications 244
Newest
Published on Mar 6, 2019in Scientific Reports 4.01
S. Pelusi11
Estimated H-index: 11
(Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico),
Guido Alessandro Baselli2
Estimated H-index: 2
(Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)
+ 19 AuthorsSalvatore Petta38
Estimated H-index: 38
(University of Palermo)
Nonalcoholic fatty liver disease (NAFLD) is a rising cause of hepatocellular carcinoma (HCC). We examined whether inherited pathogenic variants in candidate genes (n = 181) were enriched in patients with NAFLD-HCC. To this end, we resequenced peripheral blood DNA of 142 NAFLD-HCC, 59 NAFLD with advanced fibrosis, and 50 controls, and considered 404 healthy individuals from 1000 G. Pathogenic variants were defined according to ClinVar, likely pathogenic as rare variants predicted to alter protein...
Published on Apr 1, 2018in Clinical Gastroenterology and Hepatology 7.96
Rodolfo Calarco (UCSC: Catholic University of the Sacred Heart), G.L. Rapaccini20
Estimated H-index: 20
(UCSC: Catholic University of the Sacred Heart),
Luca Miele28
Estimated H-index: 28
(UCSC: Catholic University of the Sacred Heart)
Published on Jul 5, 2019in Nature Reviews Gastroenterology & Hepatology 23.57
Valerio Nobili49
Estimated H-index: 49
(Sapienza University of Rome),
Anna Alisi37
Estimated H-index: 37
(Boston Children's Hospital)
+ 3 AuthorsNaim Alkhouri26
Estimated H-index: 26
Nonalcoholic fatty liver disease (NAFLD) has rapidly become the most common form of chronic liver disease in children and adolescents. Over the past 5 years, developments have revolutionized our understanding of the genetic factors, natural history, diagnostic modalities and therapeutic targets for this disease. New polymorphisms, such as those in PNPLA3, TM6SF2, MBOAT7 and GCKR, have been identified and used to predict the development and severity of NAFLD in both adults and children, and their...
Published on Mar 1, 2019in Journal of Hepatology 18.95
Mayada Metwally2
Estimated H-index: 2
(USYD: University of Sydney),
Ali Bayoumi1
Estimated H-index: 1
(USYD: University of Sydney)
+ 16 AuthorsMaría Teresa Arias-Loste7
Estimated H-index: 7
Background & Aims Irisin, the cleaved extra-cellular fragment of the Fibronectin type III domain-containing protein 5 (FNDC5) is a myokine that is proposed to have favorable metabolic activity. We aimed to elucidate the currently undefined role of variants in the FNDC5 gene in non-alcoholic fatty liver disease (NAFLD). Methods We prioritized single nucleotide polymorphisms in FNDC5 on the basis of their putative biological function and identified rs3480 in the 3′ untranslated region (3′UTR). We ...
Published on Mar 1, 2019in Digestive and Liver Disease 3.04
Marco Biolato9
Estimated H-index: 9
,
G. Marrone5
Estimated H-index: 5
+ 9 AuthorsSalvatore Agnes19
Estimated H-index: 19
Published on Feb 1, 2019in Digestive and Liver Disease 3.04
Luca Miele28
Estimated H-index: 28
,
A. Liguori2
Estimated H-index: 2
+ 17 AuthorsN. De Matthaeis
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