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Melissa Laura Fernandez
Queensland University of Technology
12Publications
4H-index
73Citations
Publications 12
Newest
Published on Feb 1, 2014in Current Rheumatology Reports 3.08
Melissa Laura Fernandez4
Estimated H-index: 4
(Queensland University of Technology),
Zee Upton30
Estimated H-index: 30
(Queensland University of Technology),
Gary K. Shooter8
Estimated H-index: 8
(Queensland University of Technology)
Chronic wounds are an important health problem because they are difficult to heal and treatment is often complicated, lengthy and expensive. For a majority of sufferers the most common outcomes are long-term immobility, infection and prolonged hospitalisation. There is therefore an urgent need for effective therapeutics that will enhance ulcer healing and patient quality of life, and will reduce healthcare costs. Studies in our laboratory have revealed elevated levels of purine catabolites in wo...
7 Citations Source Cite
Srihari Sharma (Queensland University of Technology), Rajesh Gupta8
Estimated H-index: 8
(Queensland University of Technology)
+ 4 AuthorsShooter Gary (Queensland University of Technology)
Abstract Introduction Diabetes-related ulcers are a common and severe complication of diabetes which is expected to increase in prevalence in line with projected global growth in rates of diabetes. Caring for these chronic wounds imposes a multi-billion dollar burden on the health care systems. These ulcers can prove lethal if untreated or not recognised and can lead to critical health complications. Methods To investigate underlying causes of wound chronicity, proteomic analyses of swab samples...
Source Cite
Published on Jan 1, 2013
Melissa Laura Fernandez4
Estimated H-index: 4
,
Zee Upton30
Estimated H-index: 30
,
Gary K. Shooter8
Estimated H-index: 8
Chronic wounds are an important health problem because they are difficult to heal and treatment is often complicated, lengthy and expensive. For a majority of sufferers the most common outcomes are long-term immobility, infection and prolonged hospitalisation. There is therefore an urgent need for effective therapeutics that will enhance ulcer healing and patient quality of life, and will reduce healthcare costs. Studies in our laboratory have revealed elevated levels of purine catabolites in wo...
Published on Apr 1, 2012in International Wound Journal 2.38
Melissa Laura Fernandez4
Estimated H-index: 4
(Queensland University of Technology),
Zee Upton30
Estimated H-index: 30
(Queensland University of Technology)
+ 2 AuthorsGary K. Shooter8
Estimated H-index: 8
(Queensland University of Technology)
Chronic venous leg ulcers are a major health issue and represent an often overlooked area of biomedical research. Nevertheless, it is becoming increasingly evident that new approaches to enhance healing outcomes may arise through better understanding the processes involved in the formation of chronic wounds. We have for the first time shown that the terminal purine catabolite uric acid (UA) is elevated in wound fluid (WF) from chronic venous leg ulcers with relative concentrations correlating wi...
24 Citations Source Cite
Published on Jan 1, 2012
Daniel Broszczak4
Estimated H-index: 4
,
Dario Stupar2
Estimated H-index: 2
+ 5 AuthorsMelissa Laura Fernandez4
Estimated H-index: 4
The lack of fundamental knowledge on the biological processes associated with wound healing represents a significant challenge. Understanding the biochemical changes that occur within a chronic wound could provide insights into the wound environment and enable more effective wound management. We report on the stability of wound fluid samples under various conditions and describe a high-throughput approach to investigate the altered biochemical state within wound samples collected from various ty...
6 Citations
Published on Jan 1, 2012
Dario Stupar2
Estimated H-index: 2
,
Tony J. Parker7
Estimated H-index: 7
+ 2 AuthorsMelissa Laura Fernandez4
Estimated H-index: 4
Published on Jun 1, 2012
Daniel Broszczak4
Estimated H-index: 4
,
Dario Stupar2
Estimated H-index: 2
+ 5 AuthorsMelissa Laura Fernandez4
Estimated H-index: 4
Free to read The lack of fundamental knowledge on the biological processes associated with wound healing represents a significant challenge. Understanding the biochemical changes that occur within a chronic wound could provide insights into the wound environment and enable more effective wound management. We report on the stability of wound fluid samples under various conditions and describe a high-throughput approach to investigate the altered biochemical state within wound samples collected fr...
Published on Oct 4, 2012
Melissa Laura Fernandez4
Estimated H-index: 4
,
Zee Upton30
Estimated H-index: 30
+ 2 AuthorsGary K. Shooter8
Estimated H-index: 8
Chronic venous leg ulcers are a major health issue and represent an often overlooked area of biomedical research. Nevertheless, it is becoming increasingly evident that new approaches to enhance healing outcomes may arise through better understanding the processes involved in the formation of chronic wounds. We have for the first time shown that the terminal purine catabolite uric acid (UA) is elevated in wound fluid (WF) from chronic venous leg ulcers with relative concentrations correlating wi...
Published on Jan 1, 2010
Melissa Laura Fernandez4
Estimated H-index: 4
Chronic venous leg ulcers are a detrimental health issue plaguing our society, resulting in long term pain, immobility and decreased quality of life for a large proportion of sufferers. The frequency of these chronic wounds has led current research to focus on the wound environment to provide important information regarding the prolonged, fluctuated or static healing patterns of these wounds. Disruption to the normal wound healing process results in release of multiple factors in the wound envir...
1 Citations
12