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Kiyomi Masuda
Yokohama City University
11Publications
6H-index
119Citations
Publications 11
Newest
#1Kazutaka Aoki (YCU: Yokohama City University)H-Index: 15
#2Hiroshi Kamiyama (YCU: Yokohama City University)H-Index: 6
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 7 authors...
We previously reported that combination therapy with an α-glucosidase inhibitor (αGI) and a dipeptidyl peptidase-4 (DPP-4) inhibitor increased active glucagon-like peptide-1 (GLP-1) levels and decreased total glucose-dependent insulinotropic polypeptide (GIP) levels, compared with monotherapy, in non-diabetic men. However, the peptide YY (PYY), cholecystokinin (CCK), ghrelin, and obestatin levels in patients receiving a combination of αGIs and DPP-4 inhibitors have not been previously reported. ...
7 CitationsSource
#1Kiyomi Masuda (YCU: Yokohama City University)H-Index: 6
#2Kazutaka Aoki (YCU: Yokohama City University)H-Index: 15
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 16 authors...
Objective: We investigated the effect of addition of alogliptin, while continuing the α-glucosidase inhibitor (αGI) administration at the same or reduced dose, or discontinuing the drug, on the glycemic control in type 2 diabetic patients showing inadequate response to αGI treatment. Research design and methods: A prospective, randomized, controlled, multicenter interventional study trial. Subjects were randomly assigned to treatment with alogliptin alone (Intake 0 group), or alogliptin in addit...
6 CitationsSource
#1Kiyomi Masuda (YCU: Yokohama City University)H-Index: 6
#2Kazutaka Aoki (YCU: Yokohama City University)H-Index: 15
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 6 authors...
Background: The recommended total dietary energy intake prescribed medical nutrition therapy for obese or overweight patients with type 2 diabetes in Japan is often set at 25 kcal/kg ideal body weight (IBW)/day. This study was conducted to determine the impact of the total dietary energy intake (25 or 30 kcal/kg IBW/day) on the glycemic control, lipid profile, and satisfaction level in overweight patients with type 2 diabetes. M ethods : We performed interview and a designed prospective, randomi...
Source
#1Kazutaka Aoki (YCU: Yokohama City University)H-Index: 15
#2Hiroshi Kamiyama (YCU: Yokohama City University)H-Index: 6
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 6 authors...
We recently reported that the administration of miglitol alone just before breakfast improved postprandial hyperglycemia and increased active glucagon-like peptide-1 (GLP-1) levels after lunch in men without diabetes. Miglitol and dipeptidyl peptidase-4 inhibitors, such as sitagliptin, enhance plasma active GLP-1 concentrations via different mechanisms; therefore, combined therapy with these agents was more effective than monotherapy. In this study, we compared the effectiveness of the administr...
29 CitationsSource
#1Kiyomi Masuda (YCU: Yokohama City University)H-Index: 6
#2Kazutaka Aoki (YCU: Yokohama City University)H-Index: 15
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 3 authors...
4 CitationsSource
#1Kazutaka Aoki (YCU: Yokohama City University)H-Index: 15
#2Hiroshi Kamiyama (YCU: Yokohama City University)H-Index: 6
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 5 authors...
Mosapride citrate, a selective agonist of the 5-hydroxytryptaine (5-HT)4 receptor, is typically used to treat heartburn, nausea, and vomiting associated with chronic gastritis or to prepare for a barium enema X-ray examination. Mosapride citrate reportedly improves insulin sensitivity in patients with type 2 diabetes. As mosapride citrate activates the motility of the gastrointestinal tract, we hypothesized that mosapride citrate affects incretin secretion. We examined the effect of the administ...
8 CitationsSource
#1Kiyomi Masuda (YCU: Yokohama City University)H-Index: 6
#2Kazutaka AokiH-Index: 15
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 3 authors...
ABSTRACTAims/Introduction: One of the reasons for the poor adherence to a-glucosidase inhibitor (aGI) treatment is the need to takemedication three times a day. We hypothesized that the administ ration of miglitol might be effective for the next meal if themiglitol-induced inhibition of a-glucosidase activity persists until the next meal. In the present study, we evaluated whether theadministration of miglitol just before or after breakfast was effective for postprandial glucose excursion after ...
12 CitationsSource
#1Kiyomi MasudaH-Index: 6
#2Kazutaka AokiH-Index: 15
Last.Yu TogashiH-Index: 13
view all 3 authors...
#1Kiyomi MasudaH-Index: 6
#2Kazutaka AokiH-Index: 15
Last.Yasuo TerauchiH-Index: 58
view all 11 authors...
Abstract Background: To self-inject insulin, individuals with diabetes must be able to attach the needle to the injector, recognize the appropriate insulin dosage, detach the needle from the injector, and perform a series of operations necessary for the actual injection. These tasks require a grip strength that is strong enough to hold the necessary devices, eyesight, the use of both hands, and at least a minimum intellectual capacity. Subjects who are unable to grasp or handle the devices requi...
3 CitationsSource
#1Kazutaka Aoki (YCU: Yokohama City University)H-Index: 15
#2Kiyomi Masuda (YCU: Yokohama City University)H-Index: 6
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 5 authors...
α-glucosidase inhibitors (αGIs) increase active glucagon-like peptide-1 (GLP-1) and reduce the total glucosedependent insulinotropic polypeptide (GIP) levels, but their ability to prevent diabetes remains uncertain. Dipeptidyl peptidase-4 (DPP-4) inhibitors, such as sitagliptin, increase active GLP-1 and GIP levels and improve hyperglycemia in a glucose-dependent fashion. However, the effectiveness of their combination in subjects with normal glucose tolerance (NGT) or impaired glucose tolerance...
42 CitationsSource
12