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Alexandre Wagner Silva de Souza
Federal University of São Paulo
Physical therapyVasculitisArteritisDiabetes mellitusMedicine
64Publications
13H-index
676Citations
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Publications 65
Newest
#1Sarah L. Mackie (University of Leeds)H-Index: 19
#2Christian Dejaco (University of Graz)H-Index: 27
Last. Alexandre Wagner Silva de Souza (UNIFESP: Federal University of São Paulo)H-Index: 13
view all 36 authors...
1 CitationsSource
#1Scheila Fritsch (UFPR: Federal University of Paraná)H-Index: 2
#2Rafaela Copês (UFPR: Federal University of Paraná)
Last. Alexandre Wagner Silva de Souza (UNIFESP: Federal University of São Paulo)H-Index: 13
view all 7 authors...
Background The Indian Takayasu Clinical Activity Score (ITAS2010) was developed in 2010 as an assessment tool for disease activity in patients with Takayasu arteritis (TA). It has since been widely used in different studies and in clinical practice for the management of patients with TA. The present study aims to translate the ITAS2010 into Brazilian Portuguese language and to validate it for use in clinical practice in Brazil.
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#1Mariana Freitas de Aguiar (UNIFESP: Federal University of São Paulo)
#2Anna L. Faria-Janes (UNIFESP: Federal University of São Paulo)
Last. Alexandre Wagner Silva de Souza (UNIFESP: Federal University of São Paulo)H-Index: 13
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Abstract Introduction and Objectives Cryoglobulinemia is one of the most frequent extrahepatic manifestations of chronic hepatitis C virus (HCV) infection and it may evolve to cryoglobulinemic vasculitis (CryoVas) which is a systemic vasculitis that affects small-sized vessels. The objective of this study was to evaluate the prevalence of cryoglobulinemia and CryoVas in HCV patients in Sao Paulo, Brazil. Materials and methods A cross-sectional study was conducted and included sixty-eight viremic...
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#1Luiz Samuel Gomes Machado (UNIFESP: Federal University of São Paulo)H-Index: 2
#2Ana Cecília Diniz Oliveira (UNIFESP: Federal University of São Paulo)H-Index: 6
Last. Emília Inoue Sato (UNIFESP: Federal University of São Paulo)H-Index: 19
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Endothelial progenitor cells (EPCs) are responsible for endothelial damage repair. Takayasu’s arteritis (TA) is a chronic inflammatory disease that affects large vessels. The aim of the study was to evaluate the number of EPCs and the levels of vascular endothelial growth factor (VEGF) and the relationship of these variables in patients with TA. Thirty women with TA and 30 healthy controls were included. EPCs were assessed by flow cytometry and cell culture and VEGF quantification was performed ...
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#1Helena AlessiH-Index: 5
Last. Alexandre Wagner Silva de Souza (UNIFESP: Federal University of São Paulo)H-Index: 13
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Background Cognitive Dysfunction (CD) is one of the most common neuropsychiatric manifestations in systemic lupus erythematosus (SLE). CD occurs independently of structural damage(1,2 or disease activity(,3 impacts life quality(.4 Cardiovascular comorbidities, lower educational level and physical inactivity are risk factors for dementia in elderly worldwide(6 and are frequently found in SLE patients. Identifying the factors involved with CD in SLE can clarify physiopathological processes and pre...
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#1Sandro Félix Perazzio (UNIFESP: Federal University of São Paulo)H-Index: 1
#2Paulo Vítor Soeiro-Pereira (USP: University of São Paulo)H-Index: 4
Last. Luís Eduardo Coelho Andrade (UNIFESP: Federal University of São Paulo)H-Index: 32
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Background Studies have suggested that soluble factors in plasma from patients with active (aBD) and inactive (iBD) Behcet’s disease (BD) stimulate neutrophil function. Soluble CD40 ligand (sCD40L) is an important mediator of inflammation in BD. Its expression and effect on neutrophil oxidative burst and neutrophil extracellular trap (NET) release have not been characterized. In this study, we sought to investigate the role of plasma and the CD40L pathway on NET release and the oxidative burst p...
10 CitationsSource
#1Rafael Leite Pacheco (UNIFESP: Federal University of São Paulo)H-Index: 3
#2Carolina de Oliveira Cruz Latorraca (Cochrane Collaboration)H-Index: 4
Last. Rachel Riera (Cochrane Collaboration)H-Index: 14
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SummaryIntroduction Takayasu arteritis (TA) is a rare systemic vasculitis that affects large vessels often resistant to treatment and associated with high morbidity and mortality. Treatment is defied by the relapsing nature of the disease and frequent adverse effects of corticosteroids and immunosuppressors, rendering failure of treatment in a significant portion of patients. Considering the low quantity and quality of published studies focusing on treatment of TA, synthesis and critical assessm...
2 CitationsSource
#1Bruna Savioli (UNIFESP: Federal University of São Paulo)H-Index: 1
#2Wayel H. AbdulahadH-Index: 32
Last. Alexandre Wagner Silva de Souza (UNIFESP: Federal University of São Paulo)H-Index: 13
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Abstract There is a growing need for disease related biomarkers in Takayasu arteritis (TA).The assessment of pro-inflammatory cytokines and chemokines in TA may provide a better understanding of its pathophysiology, and circulating levels of these mediators may act as biomarkers of disease activity. Serum level of interleukin 6 (IL-6) is a potential biomarker for TA, which is mostly associated with TA status and disease activity. Associations between TA and serum/plasma levels of other cytokines...
12 CitationsSource
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