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N.J. van den Berg
Boston Children's Hospital
Provocation testAsthmaInhalationMethacholineMedicine
8Publications
4H-index
162Citations
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Publications 8
Newest
#1DanneThomasH-Index: 33
#2Tadej Battelino (Boston Children's Hospital)H-Index: 40
Last. Moshe PhillipH-Index: 56
view all 34 authors...
Aims/hypothesis To assess the use of paediatric continuous subcutaneous infusion (CSII) under real-life conditions by analysing data recorded for up to 90 days and relating them to outcome.
101 CitationsSource
#2N.J. van den BergH-Index: 4
#3P.J.E. BindelsH-Index: 11
Last. W.M.C. van AalderenH-Index: 40
view all 4 authors...
#2N.J. van den Berg (Boston Children's Hospital)H-Index: 4
#3J. van der PalenH-Index: 45
Last. P.J.E. Bindels (UvA: University of Amsterdam)H-Index: 11
view all 4 authors...
BACKGROUND: Indoor exposure to mould and dampness is frequently associated with asthma symptoms with and without lung function changes. However, the mechanisms contributing to this threat to respiratory health are only partly understood. OBJECTIVE: To investigate the contribution of recent exposure to mould and dampness in the living room or bedroom to respiratory health in a general practice-based cohort of 526 asthmatic children. METHODS: Parents were questioned about home characteristics, inc...
33 CitationsSource
#2N.J. van den Berg (Boston Children's Hospital)H-Index: 4
#3J. van der PalenH-Index: 45
Last. P.J.E. Bindels (UvA: University of Amsterdam)H-Index: 11
view all 4 authors...
Abstract Objective To evaluate whether moderate to severe airway hyperresponsiveness (AHR) could be suspected with the use of routinely available clinical and environmental information. Study Design and Setting Cross-sectional study of asthma in 526 asthmatics aged 7–17 years and treated in general practice. Results Moderate to severe AHR was present in 48% ( n = 253) of the participants. The presence of inhalation allergy, nocturnal symptoms, and usage of β 2 -mimetics were significantly associ...
7 CitationsSource
#2N.J. van den BergH-Index: 4
#3J. van der Palen (Medisch Spectrum Twente)H-Index: 45
Last. W.M.C. van Aalderen (Boston Children's Hospital)H-Index: 40
view all 4 authors...
A new method to assess bronchial hyperresponsiveness (BHR) using a single concentration methacholine has already been validated in adults with asthma. Because the geometrical dimensions of the airways in children are different, the results from studies in adults cannot be extrapolated to children. In this study, we validated the single concentration methacholine inhalation provocation test (SCIPT) in children. Twenty-two children performed three methacholine inhalation challenge tests in random ...
19 CitationsSource
#2N.J. van den BergH-Index: 4
#3P.J.E. Bindels (UvA: University of Amsterdam)H-Index: 11
Last. W.M.C. van AalderenH-Index: 40
view all 4 authors...
To prevent airway remodelling and the development of irreversible airway obstruction, inhaled corticosteroids (ICS) should be introduced in an early phase of the disease. Dutch guidelines recommend ICS for children with moderate to severe asthma. To evaluate the use of ICS in relation to the severity of asthma. We evaluated asthma symptoms during 2 weeks, bronchial hyper-responsiveness (BHR), and the use of ICS in 74 children (age: 7–16) who were previously prescribed anti asthma medication in g...
Source
#2N.J. van den BergH-Index: 4
#3P.J.E. Bindels (UvA: University of Amsterdam)H-Index: 11
Last. W.M.C. van AalderenH-Index: 40
view all 4 authors...
A new method to assess bronchial responsiveness (BR) using a single concentration methacholine has already been validated in adults with asthma1. Since the geometrical dimensions of the airways in children are different, and deposition of the inhaled aerosol also differs in children, results from studies in adults cannot simply be extrapolated to children. validation of a single-concentration inhalation provocation method in children. Twenty-three subjects performed three methacholine inhalation...
Source
#2N.J. van den BergH-Index: 4
#3P.J.E. Bindels (UvA: University of Amsterdam)H-Index: 11
Last. W.M.C. van AalderenH-Index: 40
view all 4 authors...
The degree of BHR, in relation with the presence of symptoms, is generally accepted as an estimate of asthma severity. The majority of asthmatic children is treated in general practice while measurement of BHR is not being used. To assess the prevalence and severity of BHR in children with asthma in general practice. 800 Children treated in general practice who used asthma medication in the previous year were asked to participate. BHR was evaluated in 373 of these possible asthmatic children (ag...
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