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Furio Pacini
University of Siena
EndocrinologyThyroglobulinThyroid cancerThyroidMedicine
320Publications
76H-index
30kCitations
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Publications 332
Newest
#1Tania Pilli (UNISI: University of Siena)H-Index: 8
#2Silvia Cantara (UNISI: University of Siena)H-Index: 15
Last. Maria Grazia Castagna (UNISI: University of Siena)H-Index: 17
view all 6 authors...
Purpose Anaplastic thyroid cancer (ATC) is rare but with poor prognosis. TRAIL can selectively induce apoptosis in cancer cells; however, resistance is quite common. Aim of our study was to evaluate TRAIL-induced apoptosis in ATC-derived cell lines, in vitro and in vivo, and the effect of combination with tyrosine kinase inhibitors (TKIs) selective for BRAF (vemurafenib) or Akt (MK-2206).
Source
#1P. Premoli (University of Insubria)H-Index: 4
#2Maria Laura Tanda (University of Insubria)H-Index: 25
Last. L. Bartelena (University of Insubria)H-Index: 55
view all 25 authors...
Background Whether differentiated thyroid cancer (DTC) occurring concomitantly with Graves’ disease (GD) is more aggressive and bound to a less favorable outcome is controversial.
Source
#1Silvia Cantara (UNISI: University of Siena)H-Index: 15
#2C. Ricci (UNISI: University of Siena)
Last. Maria Grazia Castagna (UNISI: University of Siena)H-Index: 17
view all 6 authors...
Purpose Several single-nucleotide polymorphisms in genes encoding for transporters have been associated with serum thyroid hormone concentrations with inconsistent results. The aim of this study was to assess the clinical significance of the rs17606253 in SLC16A10 gene alone and in combination with the DIO2 Thr92Ala variation in athyreotic patients.
Source
#1Maria Grazia Castagna (UNISI: University of Siena)H-Index: 17
#2Furio Pacini (UNISI: University of Siena)H-Index: 76
Il microcarcinoma papillare della tiroide (mPTC) e generalmente un tumore con un’ottima prognosi, ma con un comportamento clinico variabile, tra forme indolenti prive di rischi nella maggioranza dei casi, e forme clinicamente rilevanti in una minoranza di casi. In un sottogruppo di pazienti il mPTC puo presentare alla diagnosi aspetti clinici e anatomo-patologici associati a una peggiore prognosi, quali la multifocalita, la bilateralita, l’estensione extratiroidea, la presenza di malattia mestas...
Source
#1Tania Pilli (UNISI: University of Siena)H-Index: 8
#2Sandro Cardinale (UNISI: University of Siena)H-Index: 3
Last. Maria Grazia Castagna (UNISI: University of Siena)H-Index: 17
view all 11 authors...
Background Prolactin may exert immunological effects. Over the years, a higher prevalence of autoimmune thyroid diseases (ATD) has been reported in patients with prolactinomas (PRLs) in areas with sufficient iodine intake.
Source
#1Marco Capezzone (UNISI: University of Siena)H-Index: 16
#2C. Secchi (UNISI: University of Siena)
Last. Maria Grazia Castagna (UNISI: University of Siena)H-Index: 17
view all 11 authors...
Purpose An increased aggressiveness of familial papillary thyroid carcinoma (FPTC) compared with sporadic form has been reported. On the contrary, the biological behavior of familial microPTC (FmPTC) is still debated. To assess if familial diseases should be considered as a negative prognostic factor in mPTC, the clinical presentation and outcome of FmPTC and sporadic mPTC (SmPTC) were compared.
Source
#1Silvia Cantara (UNISI: University of Siena)H-Index: 15
#2Eugenio Bertelli (UNISI: University of Siena)H-Index: 19
Last. Paolo Toti (UNISI: University of Siena)H-Index: 31
view all 8 authors...
Purpose Anaplastic thyroid carcinoma (ATC) is a rare, highly aggressive form of thyroid cancer (TC) characterized by an aggressive behavior and poor prognosis, resulting in patients’ death within a year. Standard treatments, such as chemo and radiotherapy, as well as tyrosine kinase inhibitors, are ineffective for ATC treatment. Cancer immunotherapy is one of the most promising research area in oncology. The PD-1/PD-L1 axis is of particular interest, in light of promising data showing a restorat...
2 CitationsSource
#1Mimi I-Nan HuH-Index: 18
#2Rossella Elisei (UniPi: University of Pisa)H-Index: 66
Last. Robert F. GagelH-Index: 58
view all 11 authors...
Source
#1Maria Grazia Castagna (UNISI: University of Siena)H-Index: 17
#2Carlotta Marzocchi (UNISI: University of Siena)H-Index: 3
Last. Silvia Cantara (UNISI: University of Siena)H-Index: 15
view all 6 authors...
Introduction MiRNAs are small endogenous non-coding RNAs implicated with gene expression regulation. Changes in miRNA levels have been reported in thyroid cancer. Fine-needle aspiration cytology (FNAC) is the most reliable tool for differential diagnosis of thyroid nodules.
2 CitationsSource
#1Kayo Togawa (IARC: International Agency for Research on Cancer)H-Index: 4
#2Hyeong Sik Ahn (KU: Korea University)H-Index: 18
Last. Joachim Schüz (IARC: International Agency for Research on Cancer)H-Index: 40
view all 16 authors...
1 CitationsSource
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