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Yasuo Terauchi
Yokohama City University
378Publications
58H-index
23.3kCitations
Publications 385
Newest
#1Jun Shirakawa (YCU: Yokohama City University)H-Index: 16
#2Kazuki Tajima (YCU: Yokohama City University)H-Index: 12
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 11 authors...
Sodium–glucose cotransporter 2 (SGLT2) inhibitors, which prevent the renal reabsorption of glucose, decrease blood glucose levels in an insulin-independent manner. We previously reported creating a mouse model of systemic inhibition of target receptors for both insulin and IGF-1 by treating animals with OSI-906, a dual insulin/IGF-1 receptor inhibitor, for 7 days. The OSI-906-treated mice exhibited an increased beta cell mass, hepatic steatosis and adipose tissue atrophy, accompanied by hypergly...
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#1Ikuro MatsubaH-Index: 14
#2Akira KanamoriH-Index: 12
Last.Mizuki KaneshiroH-Index: 7
view all 23 authors...
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#1Aika Miya (Hokkaido University)H-Index: 2
#2Akinobu Nakamura (Hokkaido University)H-Index: 16
Last.Tatsuya Atsumi (Hokkaido University)H-Index: 44
view all 9 authors...
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#1Jun Shirakawa (YCU: Yokohama City University)H-Index: 16
#2Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
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#1Jun Shirakawa (YCU: Yokohama City University)H-Index: 16
#2Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
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#1Takashi Miyazaki (YCU: Yokohama City University)H-Index: 4
#2Jun Shirakawa (YCU: Yokohama City University)H-Index: 16
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 13 authors...
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#1Sho Kinguchi (YCU: Yokohama City University)H-Index: 4
#2Hiromichi Wakui (YCU: Yokohama City University)H-Index: 17
Last.Kouichi Tamura (YCU: Yokohama City University)H-Index: 27
view all 29 authors...
The Y-AIDA study was designed to investigate the renal- and home blood pressure (BP)-modulating effects of add-on dapagliflozin treatment in Japanese individuals with type 2 diabetes mellitus (T2DM) and albuminuria. We conducted a prospective, multicenter, single-arm study. Eighty-six patients with T2DM, HbA1c 7.0–10.0%, estimated glomerular filtration rate (eGFR) ≥ 45 mL/min/1.73 m2, and urine albumin-to-creatinine ratio (UACR) ≥ 30 mg/g creatinine (gCr) were enrolled, and 85 of these patients ...
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#1Yuzuru Ito (YCU: Yokohama City University)H-Index: 7
#2Mitsuyo Kaji (YCU: Yokohama City University)H-Index: 5
Last.Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
view all 4 authors...
The brain and nervous system play an important role in pancreatic β-cell function. This study investigated the role of muscarinic agonists or acetylcholine, which is the major neurotransmitter in the vagal nerve, in regulating pancreatic β-cell mass and glucose homeostasis. Administration of the muscarinic agonist bethanechol increased insulin secretion and improved glucose tolerance in insulin-receptor substrate 2 (IRS2)-knockout (IRS-2−/−) mice and diet-induced obesity mice. Oral administratio...
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#1Masahiro Takihata (YCU: Yokohama City University)H-Index: 6
#2Yasuo Terauchi (YCU: Yokohama City University)H-Index: 58
ABSTRACTBackground: The efficacy and safety of SGLT-2 and DPP-4 inhibitor monotherapies in T2DM is well established; however, data on the effect of combination therapies and sequence of administrat...
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