Athene Lane
University of Bristol
Publications 104
#1Kalina Biernacka (UoB: University of Bristol)H-Index: 5
#2Jeffrey M P HollyH-Index: 55
Last.Athene LaneH-Index: 14
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Whether prostate cancer (PCa) may be preventable by dietary interventions can be assessed in randomized trials using intermediate biomarkers of cancer risk or progression. We investigated whether lycopene or green tea modify circulating insulin-like growth factor (IGF) peptides in men at increased r
#1Matthew HickmanH-Index: 64
#2John F. Dillon (Dund.: University of Dundee)H-Index: 36
Last.Sharon J. Hutchinson (GCU: Glasgow Caledonian University)H-Index: 42
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Introduction Hepatitis C virus (HCV) is the second largest contributor to liver disease in the UK, with injecting drug use as the main risk factor among the estimated 200 000 people currently infected. Despite effective prevention interventions, chronic HCV prevalence remains around 40% among people who inject drugs (PWID). New direct-acting antiviral (DAA) HCV therapies combine high cure rates (>90%) and short treatment duration (8 to 12 weeks). Theoretical mathematical modelling evidence sugge...
#1Rhona Beynon (UoB: University of Bristol)H-Index: 2
#2Rebecca C Richmond (UoB: University of Bristol)H-Index: 20
Last.Richard M. Martin (UoB: University of Bristol)H-Index: 102
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Lycopene and green tea consumption have been observationally associated with reduced prostate cancer risk, but the underlying mechanisms have not been fully elucidated. We investigated the effect of factorial randomisation to a 6‐month lycopene and green tea dietary advice or supplementation intervention on 159 serum metabolite measures in 128 men with raised PSA levels (but prostate cancer‐free), analysed by intention‐to‐treat. The causal effects of metabolites modified by the intervention on p...
1 CitationsSource
#1Hiroki ItoH-Index: 17
#2Grace J. YoungH-Index: 5
Last.Marcus J. DrakeH-Index: 36
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#1Hashim HashimH-Index: 18
#2Athene LaneH-Index: 14
Last.Paul AbramsH-Index: 75
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#1Marco MatejcicH-Index: 1
#2Ed SaundersH-Index: 23
Last.Marie SanchezH-Index: 16
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The original version of this Article contained an error in the spelling of the author Manuela Gago-Dominguez, which was incorrectly given as Manuela G. Dominguez. This has now been corrected in both the PDF and HTML versions of the Article.
#1Marco MatejcicH-Index: 1
#2Ed SaundersH-Index: 23
Last.Marie SanchezH-Index: 16
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Germline variation at 8q24 and prostate cancer risk in men of European ancestry (vol 9, 4616, 2018)
#1Tokhir DadaevH-Index: 13
#2Ed SaundersH-Index: 23
Last.Zsofia Kote-JaraiH-Index: 43
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Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable selection algorithm JAM to fine-map 84 prostate cancer susceptibility loci, using summary data from a large European ancestry meta-analysis. We observe evidence for multiple independent signals at 12 regions and 99 risk signals overall. Only 15 original GWAS tag SNPs remain among t...
21 CitationsSource