Steven E. Reis
University of Pittsburgh
Publications 236
#1Vanathi Gopalakrishnan (University of Pittsburgh)H-Index: 16
#2Jeya Balaji Balasubramanian (University of Pittsburgh)H-Index: 4
Last.Steven E. Reis (University of Pittsburgh)H-Index: 52
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Biomarker discovery is critical for both biomedical research and for clinical diagnostic, prognostic, and therapeutic decision-making. They help improve our understanding of the underlying physiological processes within an individual. Discovery of biomarkers from complex biomedical datasets is done using data mining algorithms. Hundreds of thousands of biomarkers have been discovered and reported in literature but only a few dozen have been found to be clinically useful. This discrepancy is beca...
#1Eric A. Bucklew (University of Pittsburgh)
#2Steven E. Reis (University of Pittsburgh)H-Index: 52
Last.Krishna Kancharla (University of Pittsburgh)H-Index: 2
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#1Ahmed AlBadri (Emory University)H-Index: 2
#2C. Noel Bairey Merz (Cedars-Sinai Medical Center)H-Index: 71
Last.Bina Ahmed (Dartmouth–Hitchcock Medical Center)H-Index: 4
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Abstract Background Currently as many as one-half of women with suspected myocardial ischemia have no obstructive coronary artery disease (CAD), and abnormal coronary reactivity (CR) is commonly found. Objectives The authors prospectively investigated CR and longer-term adverse cardiovascular outcomes in women with and with no obstructive CAD in the National Heart, Lung, and Blood Institute–sponsored WISE (Women’s Ischemia Syndrome Evaluation) study. Methods Women (n = 224) with signs and sympto...
8 CitationsSource
#1C. Noel Bairey Merz (Cedars-Sinai Medical Center)H-Index: 71
#2Marian B. Olson (University of Pittsburgh)H-Index: 34
Last.Eileen M. Handberg (UF: University of Florida)H-Index: 39
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Background We previously reported in a cross-sectional analysis an adverse relationship between weight cycling and HDL-cholesterol but not angiographic obstructive coronary artery disease (CAD) among women undergoing coronary angiography for suspected ischemia in the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE). We now examine the relationship between weight cycling and prospective adverse cardiovascular outcome in this group. Methods 795 women enrolled between 1996–2001 in the WI...
#1Daniel Shpilsky (University of Pittsburgh)H-Index: 2
#2Claudia Bambs (UC: Pontifical Catholic University of Chile)H-Index: 11
Last.Sebhat Erqou (Brown University)H-Index: 2
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3 CitationsSource
#1Shyam Visweswaran (University of Pittsburgh)H-Index: 19
#2Michael J. Becich (University of Pittsburgh)H-Index: 41
Last.Steven E. Reis (University of Pittsburgh)H-Index: 52
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Author(s): Visweswaran, S; Becich, MJ; D'Itri, VS; Sendro, ER; MacFadden, D; Anderson, NR; Allen, KA; Ranganathan, D; Murphy, SN; Morrato, EH; Pincus, HA; Toto, R; Firestein, GS; Nadler, LM; Reis, SE | Abstract: The Accrual to Clinical Trials (ACT) network is a federated network of sites from the National Clinical and Translational Science Award (CTSA) Consortium that has been created to significantly increase participant accrual to multi-site clinical trials. The ACT network represents an unpre...
4 CitationsSource
#1Daniel Shpilsky (University of Pittsburgh)H-Index: 2
#2Sebhat Erqou (University of Pittsburgh)H-Index: 19
Last.Oladipupo Olafiranye (University of Pittsburgh)H-Index: 9
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Studies have reported an association between obstructive sleep apnea (OSA) and cardiovascular disease (CVD) morbidity and mortality. Proposed mechanisms include endothelial dysfunction and atherosclerosis. We aimed to investigate the associations of OSA with endothelial dysfunction and subclinical atherosclerotic coronary artery disease (CAD), and assess the impact of race on these associations. We used data from the Heart Strategies Concentrating on Risk Evaluation (Heart SCORE) study, a commun...
4 CitationsSource
#1Janet M. Catov (University of Pittsburgh)H-Index: 34
#2Matthew F. Muldoon (University of Pittsburgh)H-Index: 56
Last.W.T. Parks (University of Pittsburgh)H-Index: 5
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Objective Preterm birth (PTB) is associated with excess maternal cardiovascular disease risk. We considered that women with PTB and placental evidence of maternal malperfusion would be particularly affected. Design Pregnancy cohort study. Setting Pittsburgh, PA, USA. Population Women with PTB (n = 115) and term births (n = 210) evaluated 4–12 years after pregnancy. Methods Cardiometabolic risk markers were compared in women with prior PTB versus term births; pre-eclampsia and growth restriction ...
6 CitationsSource
#1Sebhat Erqou (University of Pittsburgh)H-Index: 19
#2Oluremi N Ajala (University of Pittsburgh)H-Index: 6
Last.Steven E. Reis (University of Pittsburgh)H-Index: 52
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Background Determination of the correlation of ideal cardiovascular health variables among spousal or cohabitating partners may guide the development of couple‐based interventions to reduce cardiovascular disease risk. Method and Results We used data from the HeartSCORE (Heart Strategies Concentrating on Risk Evaluation) study. Ideal cardiovascular health, defined by the American Heart Association, comprises nonsmoking, body mass index 2 , physical activity at goal, diet consistent with guidelin...
Objective— We aimed to assess racial differences in air pollution exposures to ambient fine particulate matter (particles with median aerodynamic diameter 2.5 ]) and black carbon (BC) and their association with cardiovascular disease (CVD) risk factors, arterial endothelial function, incident CVD events, and all-cause mortality. Approach and Results— Data from the HeartSCORE study (Heart Strategies Concentrating on Risk Evaluation) were used to estimate 1-year average air pollution exposure to P...
10 CitationsSource