R. Toro
University of Cádiz
Publications 61
Published on Aug 1, 2019in Translational Research4.92
Maria Calderon-Dominguez (UCA: University of Cádiz), Thalía Belmonte (UCA: University of Cádiz)+ 10 AuthorsVicenta Llorente-Cortés23
Estimated H-index: 23
(CSIC: Spanish National Research Council)
Dilated cardiomyopathy (DCM) is a heart muscle disease characterized by ventricular dilation and systolic dysfunction in the absence of abnormal loading conditions or coronary artery disease. This cardiac disorder is a major health problem due to its high prevalence, morbidity, and mortality. DCM is a complex disease with a common phenotype but heterogeneous pathological mechanisms. Early etiological diagnosis and prognosis stratification is crucial for the clinical management of the patient. Ad...
Published on 2019in Atherosclerosis4.25
David de Gonzalo-Calvo12
Estimated H-index: 12
David Viladés3
Estimated H-index: 3
+ 7 AuthorsSonia Benitez22
Estimated H-index: 22
Published on Jun 1, 2019in European Geriatric Medicine1.23
M. Ramos1
Estimated H-index: 1
D. M. Quezada + 3 AuthorsR. Toro8
Estimated H-index: 8
Aim Analyse which factors could influence in earlier hospitalizations for congestive heart failure in geriatric patients with degenerative aortic stenosis.
Published on Mar 29, 2019in Bioscience Reports2.54
Carlos Zaragoza20
Estimated H-index: 20
Marta Saura15
Estimated H-index: 15
+ 5 AuthorsR. Toro8
Estimated H-index: 8
A new familial dilated cardiomyopathy (FDCM) was found related to mutations in BAG3 gene. MicroRNAs (miRNAs) represent new targets of FDCM, although no studies have assessed clinical association between Bcl2-associated athanogene 3 (BAG3)-related DCM and miRNAs. Here, we studied whether a clinical association between BAG3-related FDCM and circulating miRNAs may have diagnostic and prognostic value in a small cohort of familial related individuals carrying a BAG3 mutation (BAG3+) and/or diagnosed...
Published on Jan 1, 2019
Miguel Ángel Sánchez Chaparro8
Estimated H-index: 8
(UMA: University of Málaga),
Pablo Perez-Martinez42
Estimated H-index: 42
(UCO: University of Córdoba (Spain))
+ 22 AuthorsMarta Bueno3
Estimated H-index: 3
Abstract The Spanish Arteriosclerosis Society has accredited more than 70 lipid units across the country. The main criteria for patients to be referred to these units are presented. These are not only grouped by the type of dyslipidaemia or the lipid levels, but also on certain clinical characteristics suggesting primary hyperlipidaemia, a complex diagnosis, or difficult management due to inefficacy, or side effects.
Published on Nov 1, 2018in Journal of the American College of Cardiology18.64
Fernando Dominguez8
Estimated H-index: 8
Sofía Cuenca5
Estimated H-index: 5
+ 67 AuthorsMaria Franaszczyk1
Estimated H-index: 1
Abstract Background The BAG3 (BLC2-associated athanogene 3) gene codes for an antiapoptotic protein located on the sarcomere Z-disc. Mutations in BAG3 are associated with dilated cardiomyopathy (DCM), but only a small number of cases have been reported to date, and the natural history of BAG3 cardiomyopathy is poorly understood. Objectives This study sought to describe the phenotype and prognosis of BAG3 mutations in a large multicenter DCM cohort. Methods The study cohort comprised 129 individu...
Published on Oct 19, 2018in International Journal of Molecular Sciences4.18
Rafael Ramírez-Carracedo1
Estimated H-index: 1
Laura Tesoro + 7 AuthorsCarlos Zaragoza20
Estimated H-index: 20
Lack of endothelial nitric oxide causes endothelial dysfunction and circulating monocyte infiltration, contributing to systemic atheroma plaque formation in arterial territories. Among the different inflammatory products, macrophage-derived foam cells and smooth muscle cells synthesize matrix metalloproteinases (MMPs), playing a pivotal role in early plaque formation and enlargement. We found increased levels of MMP-9 and MMP-13 in human endarterectomies with advanced atherosclerosis, together w...
Published on Aug 1, 2018in Journal of Molecular Medicine
R. Toro8
Estimated H-index: 8
(UCA: University of Cádiz),
Sara Blasco-Turrión1
Estimated H-index: 1
+ 10 AuthorsFelix Rosa Longobardo (UCA: University of Cádiz)
This work was supported by the Fundacion Publica Andaluza Progreso y Salud para la Financiacion de la I+i Biomedica y en Ciencias de las Salud en Andalucia (PI-0011/2014) and a grant in the framework of the Integrated Territorial Initiative (ITI)2014-2020 for the province of Cadiz by the Ministry of Health and the European Regional Developement Fund (ERDF) PI0048-2017 (project co-finantiated 80% by funds from the ERDF operational program of Andalusia 2014-2020) (ITI 0048-2017). This work was als...
Published on May 23, 2018in Clinical Science5.24
Clarissa P.C. Gomes3
Estimated H-index: 3
David de Gonzalo-Calvo5
Estimated H-index: 5
(CSIC: Spanish National Research Council)
+ 4 AuthorsYvan Devaux2
Estimated H-index: 2
There is overwhelming evidence that regular exercise training is protective against cardiovascular disease (CVD), the main cause of death worldwide. Despite the benefits of exercise, the intricacies of their underlying molecular mechanisms remain largely unknown. Non-coding RNAs (ncRNAs) have been recognized as a major regulatory network governing gene expression in several physiological processes and appeared as pivotal modulators in a myriad of cardiovascular processes under physiological and ...
Published on Dec 1, 2017in European Journal of Emergency Medicine1.38
Gonzalo Barón-Esquivias18
Estimated H-index: 18
Agustín Fernández-Cisnal2
Estimated H-index: 2
+ 6 AuthorsÁngel Martínez11
Estimated H-index: 11
AimTo apply, analyze, and evaluate the four syncope risk scores recommended by the 2009 European guidelines and the different parameters that they use to predict death, syncope recurrence, and hospital readmission in the population seen in the emergency room department (ERD) for syncope.Methods and