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Serife Medeni Solmaz
Dokuz Eylül University
9Publications
1H-index
5Citations
Publications 9
Newest
Published on Oct 1, 2018in Journal of Laboratory Physicians
Serife Medeni Solmaz1
Estimated H-index: 1
,
Ozcan Uzun + 8 AuthorsMehmet Ali Özcan15
Estimated H-index: 15
(Dokuz Eylül University)
BACKGROUND: Recent reports showed neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR), as a predictor of progression-free survival (PFS) and overall survival (OS) in various malignancies. MATERIALS AND METHODS: We retrospectively examined the PLR, NLR, and MLR in a cohort of 186 newly diagnosed multiple myeloma (MM) patients. This study investigated the prognostic relevance of NLR, PLR, and MLR in MM patients. NLR, PLR, and MLR were ca...
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Serife Medeni Solmaz1
Estimated H-index: 1
,
Selda Kahraman1
Estimated H-index: 1
(Medical Park)
+ 8 AuthorsBulent Undar11
Estimated H-index: 11
(Dokuz Eylül University)
Peripheral blood is the prefered source for hematopoietic stem cells for hematopoietic stem cell transplantation. The efficiency of peripheral blood stem cell (PBSC) collection can vary among devices. In this study we aimed to compare feasibility and effectivity of apheresis procedures of the different systems. Two apheresis systems [Com.Tec (Fresenius Healthcare) and Spectra Optia (Caridian BCT)] were used in our center for the collection of PBSCs for autologous and allogeneic transplantation. ...
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Published on Dec 7, 2017in Blood 16.56
Omur Gokmen Sevindik1
Estimated H-index: 1
(Fırat University),
Mustafa Pehlivan14
Estimated H-index: 14
(University of Gaziantep)
+ 20 AuthorsVildan Ozkocaman14
Estimated H-index: 14
(Uludağ University)
Introduction: Pomalidomide is a potent immunomodulatory drug (imid) with efficacy demonstrated in relapsed refractory multiple myeloma. In a phase 3 study, pomalidomide showed a benefit of PFS and OS over high dose dexamethasone, even in proteasome inhibitor and imid refractory patients. In our country, Pomalidomide has recently gained approval in relapsed refractory setting in patients who were both refractory to a proteasome inhibitor and an immunomodulatory drug. Before this approval we were ...
Published on Apr 1, 2016in Experimental Hematology 2.46
Ayşe Pınar Erçetin1
Estimated H-index: 1
(Dokuz Eylül University),
Mehmet Ali Özcan15
Estimated H-index: 15
(Dokuz Eylül University)
+ 6 AuthorsBulent Undar11
Estimated H-index: 11
(Dokuz Eylül University)
Multiple myeloma (MM) is a hematologic cancer characterized by malignant proliferation of plasma cells and their precursors. Immunosuppressive CD4+CD25+Foxp3+ regulatory T (Treg) cells are increased in the peripheral blood of patients with MM. On the basis of this finding, we sought to evaluate the ex vivo effect of CD4+CD25+Foxp3+ Treg cells on the anti-tumor effect of the proteosome inhibitor bortezomib on MM cells. We collected peripheral blood and bone marrow aspiration samples from 20 patie...
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Published on Sep 2, 2015in Leukemia & Lymphoma 2.67
Ömür Gökmen Sevindik3
Estimated H-index: 3
(Dokuz Eylül University),
Zeynep Gulsum Guc2
Estimated H-index: 2
(Dokuz Eylül University)
+ 9 AuthorsFatih Demirkan11
Estimated H-index: 11
(Dokuz Eylül University)
The serum albumin (SA) level has been reported to be an independent prognostic biomarker that may serve as a surrogate representative of disease biology in patients diagnosed with myelodysplastic syndrome (MDS). However, its prognostic ability has not been tested in a model adjusting for comorbidities. We analyzed 200 patients who were diagnosed as having de novo MDS. Median overall survival (OS) of all patients was 25 months and median leukemia-free survival (LFS) was 24 months. Median OS accor...
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Published on Sep 1, 2015in Clinical Lymphoma, Myeloma & Leukemia 2.27
Ömür Gökmen Sevindik3
Estimated H-index: 3
(Dokuz Eylül University),
Inci Alacacioglu8
Estimated H-index: 8
(Dokuz Eylül University)
+ 8 AuthorsGüner Hayri Özsan5
Estimated H-index: 5
(Dokuz Eylül University)
e202 Methods: We present a series of 4 patients diagnosed with plasma cell leukemia (PCL) between 2009 and 2014. The LCP was diagnosed in these cytomorphology and by study of peripheral blood cytometry. 25% had LCP Primary BJ Lambda MM and 75% LPC Secondary. The therapeutic use in our patients was diverse and personalized; patients with Primary LPC receiving schemes with Bortezomib (25%) plus autologous stem cell transplantation and patients with Secundary LPC Dexamethasone alone (75%). Results:...
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Published on Jun 1, 2015in Clinical Lymphoma, Myeloma & Leukemia 2.27
Ömür Gökmen Sevindik3
Estimated H-index: 3
(Dokuz Eylül University),
Sinan Mersin1
Estimated H-index: 1
(Dokuz Eylül University)
+ 9 AuthorsFatih Demirkan11
Estimated H-index: 11
(Dokuz Eylül University)
Abstract Introduction Essential thrombocythemia (ET) is the most common of the myeloproliferative neoplasms. For better predicting the occurrence of thrombotic events, an International Prognostic Score of Thrombosis for ET (IPSET-Thrombosis) was recently developed. We aimed to investigate the validity of IPSET-Thrombosis in a Turkish patient cohort and to compare the efficacy of IPSET-Thrombosis and conventional risk scoring systems in predicting thrombosis-free survival. Patients and Methods We...
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Published on May 20, 2015in Journal of Clinical Oncology 28.25
Fatih Demirkan11
Estimated H-index: 11
(Dokuz Eylül University),
Ömür Gökmen Sevindik3
Estimated H-index: 3
(Dokuz Eylül University)
+ 3 AuthorsGüner Hayri Özsan5
Estimated H-index: 5
(Dokuz Eylül University)
1 Citations Source Cite
Published on Feb 1, 2013in Blood Coagulation & Fibrinolysis 1.12
Abdullah Katgi4
Estimated H-index: 4
,
Pinar Ataca2
Estimated H-index: 2
+ 6 AuthorsGüner Hayri Özsan5
Estimated H-index: 5
Gray platelet syndrome (GPS) is a rare inherited disorder characterized by the absence of a-granules and their constituents. It may be present with thrombocytopenia and bleeding tendency. Platelets have a large and gray appearance under light and electron microscope. A 19-year old female patient with her second relapse acute lymphoblastic leukemia had to be consolidated with allohematopoietic stem cell transplantation (HSCT) after achieving remission with induction chemotherapy. The only availab...
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