Match!
Emma Whitcomb
University of Calgary
PathologyImmunohistochemistryTrastuzumabGeneral surgeryMedicine
13Publications
5H-index
66Citations
What is this?
Publications 13
Newest
#1Matthew Woo (U of C: University of Calgary)H-Index: 2
#2Emma Whitcomb (U of C: University of Calgary)H-Index: 5
Last. Michael Curley (U of C: University of Calgary)H-Index: 2
view all 5 authors...
Source
#1Emma Whitcomb (U of C: University of Calgary)H-Index: 5
#2Won-Tak Choi (UCSF: University of California, San Francisco)H-Index: 12
Last. Maria Westerhoff (UW: University of Washington)H-Index: 11
view all 17 authors...
Background & Aims Most patients, even those who have received a liver transplant, achieve a sustained virologic response (SVR) to therapy for hepatitis C virus (HCV) infection. Little is known about the histologic features of liver biopsy specimens collected after SVR, particularly in patients who have received a liver transplant. We aimed to better characterize the histologic features of allograft liver biopsy specimens from patients who achieved SVR to anti-HCV therapy after liver transplantat...
9 CitationsSource
#1Craig S. Brown (U of C: University of Chicago)H-Index: 6
#2Jennifer R. Defazio (U of C: University of Chicago)H-Index: 7
Last. Lawrence J. Gottlieb (U of C: University of Chicago)H-Index: 28
view all 7 authors...
: Gastrointestinal involvement is a rare complication of toxic epidermal necrolysis syndrome (TENS) that results in sloughing of the intestinal epithelium. Prior case reports have noted the potential susceptibility of the entire gastrointestinal tract, from oropharynx and esophagus to sigmoid colon and rectum. Given its infrequency, the effect of gastrointestinal involvement on the treatment and prognosis of TENS is poorly understood. Here, the authors report a case of gastrointestinal symptoms ...
1 CitationsSource
#1Daniel V.T. Catenacci (U of C: University of Chicago)H-Index: 27
#2Wei-Li LiaoH-Index: 8
Last. Todd HembroughH-Index: 13
view all 20 authors...
Background Trastuzumab has shown a survival benefit in cases of Her2-positive gastroesophageal cancer (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for trastuzumab-based therapy. However, these low-throughput assays often produce discordant or equivocal results.
14 CitationsSource
#1Ajaypal Singh (U of C: University of Chicago)H-Index: 5
#2Uzma D. Siddiqui (U of C: University of Chicago)H-Index: 28
Last. Irving Waxman (U of C: University of Chicago)H-Index: 38
view all 9 authors...
Background and Aims EMR is increasingly used for resection of sporadic, nonampullary duodenal adenomas (SNDAs), but there are no guidelines for the management of these lesions. The aims of this study were to evaluate the safety and efficacy of EMR exclusively for SNDAs and to determine the factors predictive of outcomes. Methods We performed a retrospective review of patients with SNDAs referred for endoscopic therapy from 2006 to 2013. The outcomes studied were successful endoscopic resection, ...
10 CitationsSource
#1Ajaypal SinghH-Index: 4
Last. Irving WaxmanH-Index: 38
view all 9 authors...
Source
Source
#1Ajaypal Singh (U of C: University of Chicago)H-Index: 5
#2Uzma D. Siddiqui (U of C: University of Chicago)H-Index: 28
Last. Irving Waxman (U of C: University of Chicago)H-Index: 38
view all 10 authors...
Source
#1Daniel V.T. Catenacci (U of C: University of Chicago)H-Index: 27
#2Wei-Li LiaoH-Index: 8
Last. Todd HembroughH-Index: 13
view all 20 authors...
Abstract Background: Trastuzumab showed survival benefit for Her2-positive gastroesophageal cancers (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for trastuzumab-based therapy. However, both assays are low throughput with various limitations. Methods: We developed a selected reaction monitoring mass spectrometric (SRM-MS) assay and quantified levels (amol/ug) of Her2-SRM in cell lines (n=27) and GEC tissues (n=139). We compared He...
Source
12