Jianqiao Liu
Guangzhou Medical University
Publications 15
#1Rui Chen (Guangzhou Medical University)H-Index: 2
#2Shiping Chen (Guangzhou Medical University)H-Index: 1
Last.Jianqiao Liu (Guangzhou Medical University)H-Index: 5
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Background Overweight/obese women with polycystic ovary syndrome (PCOS) are at increased risk of subfertility and complications of pregnancy, compared with normal-weight women. To implement controlled ovarian hyperstimulation (COH), the improved efficacy of the gonadotrophin-releasing hormone antagonist (GnRH-ant) protocol has been demonstrated, as well as frozen embryo transfer (FET).
#1Zongbin Liu (Cornell University)H-Index: 5
#2Rui Chen (Guangzhou Medical University)H-Index: 1
Last.Lidong Qin (Cornell University)H-Index: 29
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#1Yuxia He (Guangzhou Medical University)H-Index: 1
#2Haiying Liu (Guangzhou Medical University)H-Index: 2
Last.Jianqiao Liu (Guangzhou Medical University)H-Index: 5
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AbstractObjective: The objective of this retrospective study was to evaluate clinical outcomes of early cumulus cells removal and early rescue intracytoplasmic sperm injection (ICSI) in high-risk patients of fertilization failure during human in vitro fertilization (IVF).Methods: A total of 5,518 patients were enrolled between January 2014 to December 2016. Of which 505 couples performed short insemination with >30% fertilization rate were included in short-term IVF group, 102 patients detected ...
#1Hanyan LiuH-Index: 1
#2Jianqiao LiuH-Index: 5
Last.Lei LiH-Index: 10
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Objective To identify the incidence and risk factors associated with IVF-conceived monozygotic twinning (MZT). Design Retrospective study. Setting Academic hospital. Patient(s) A total of 3,463 women with clinical pregnancies between January 2014 and February 2015 were analyzed. Intervention(s) None. Main Outcome Measure(s) The measures were the incidence of MZT based on the number of embryos that were replaced, type of insemination method (conventional IVF or intracytoplasmic sperm injection [I...
#1Geng An (Guangzhou Medical University)H-Index: 1
#2Zihao Zou (Guangzhou Medical University)H-Index: 1
Last.Wen Zhang (Guangzhou Medical University)H-Index: 1
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#1Lichun Tang (Protein Sciences)H-Index: 1
#2Yanting Zeng (Guangzhou Medical University)H-Index: 1
Last.Xiaowei Li (NU: Nanjing University)H-Index: 1
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Previous works using human tripronuclear zygotes suggested that the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 system could be a tool in correcting disease-causing mutations. However, whether this system was applicable in normal human (dual pronuclear, 2PN) zygotes was unclear. Here we demonstrate that CRISPR/Cas9 is also effective as a gene-editing tool in human 2PN zygotes. By injection of Cas9 protein complexed with the appropriate sgRNAs and homology donors into o...
#1Liu W (Guangzhou Medical University)H-Index: 1
#2Jinbao Liu (Guangzhou Medical University)H-Index: 20
Last.Chen D (Guangzhou Medical University)H-Index: 1
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AbstractBackground: Cell-free nuclear DNA has been isolated from spent embryo culture medium. Whether this small amount of DNA can be amplified at the whole genome level and the concordance rate of karyotypes and specific alleles between biopsied cells and media has not been evaluated.Methods: Seven couples were recruited, 88 donated embryos and their corresponding media were collected for whole genome amplification (WGA). The efficiency of WGA, the concordance of chromosome status, and the HBB ...