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Clare Moynihan
Institute of Cancer Research
63Publications
23H-index
2,840Citations
Publications 64
Newest
#1Elizabeth PageH-Index: 9
#2Elizabeth BancroftH-Index: 19
Last.Rosalind A. EelesH-Index: 93
view all 136 authors...
Abstract Background Mutations in BRCA2 cause a higher risk of early-onset aggressive prostate cancer (PrCa). The IMPACT study is evaluating targeted PrCa screening using prostate-specific-antigen (PSA) in men with germline BRCA1/2 mutations. Objective To report the utility of PSA screening, PrCa incidence, positive predictive value of PSA, biopsy, and tumour characteristics after 3 yr of screening, by BRCA status. Design, setting, and participants Men aged 40–69 yr with a germline pathogenic BRC...
1 CitationsSource
#1Geraldine Leydon (University of Southampton)H-Index: 25
#2Amy Halls (University of Surrey)H-Index: 3
Last.Paul Little (University of Southampton)H-Index: 55
view all 12 authors...
Objective: to identify call handlers’ key experiences of providing telephone help on a cancer helpline. Methods: semi‐structured qualitative interviews with 30 call handlers from three UK‐based cancer helplines. Transcribed interview data were analysed thematically. Results: thematic analysis identified three themes: (a) call handlers’ perceptions of their role on the helpline, (b) challenges of working on a helpline and (c) the need for training/keeping up with competencies. Call handlers repor...
Source
#1Joanne HavilandH-Index: 22
#2Clare MoynihanH-Index: 23
Last.Judith M. BlissH-Index: 63
view all 4 authors...
#1Christos Mikropoulos (U of C: University of Chicago)H-Index: 4
#2Christina G. Selkirk (U of C: University of Chicago)H-Index: 8
Last.Rosalind A. Eeles (U of C: University of Chicago)H-Index: 93
view all 120 authors...
BACKGROUND: Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition to PrCa due to BRCA1/2 mutations. This analysis evaluates the utility of PSA and PSAV for identifying PrCa and high-grade disease in this cohort. METHODS: PSAV was calculated using logistic regression to determine if PSA or PSAV predicted the result of prostate biopsy (PB) in m...
7 CitationsSource
#1Robert Huddart (ICR: Institute of Cancer Research)H-Index: 64
#2Alison J. Birtle (University of Manchester)H-Index: 21
Last.Emma Hall (ICR: Institute of Cancer Research)H-Index: 42
view all 15 authors...
Objectives To test the feasibility of a randomised trial in muscle-invasive bladder cancer (MIBC) and compare outcomes in patients who receive neoadjuvant chemotherapy followed by radical cystectomy (RC) or selective bladder preservation (SBP), where definitive treatment [RC or radiotherapy (RT)] is determined by response to chemotherapy. Patients and Methods SPARE is a multicentre randomised controlled trial comparing RC and SBP in patients with MIBC staged T2–3 N0 M0, fit for both treatment st...
20 CitationsSource
#1Clare Moynihan (ICR: Institute of Cancer Research)H-Index: 23
#2Elizabeth Bancroft (ICR: Institute of Cancer Research)H-Index: 19
Last.Rosalind A. Eeles (ICR: Institute of Cancer Research)H-Index: 93
view all 7 authors...
ObjectiveIncreased risk of prostate cancer (PCa) is observed in men with BRCA1/BRCA2 mutations. Sex and gender are key determinants of health and disease although unequal care exists between the sexes. Stereotypical male attitudes are shown to lead to poor health outcomes. MethodsMen with BRCA1/2 mutations and diagnosed with PCa were identified and invited to participate in a qualitative interview study. Data were analysed using a framework approach. Masculinity theory was used to report the imp...
4 CitationsSource
#1Geraldine LeydonH-Index: 25
#2Beth StuartH-Index: 20
Last.Paul LittleH-Index: 55
view all 11 authors...
Source
#1Geraldine Leydon (University of Southampton)H-Index: 25
#2Beth Stuart (University of Southampton)H-Index: 20
Last.Paul Little (University of Southampton)H-Index: 55
view all 11 authors...
There are more than 1500 UK health helplines in operation, yet we have scant knowledge about the resources in place to support the seeking and delivering of cancer-related telephone help and support. This research aimed to identify and describe cancer and cancer-related helpline service provision: the number of helplines available, the variety of services provided, and the accessibility of those services. This study used online national questionnaire survey sent to 95 cancer and cancer-related h...
Source
#1Geraldine Leydon (University of Southampton)H-Index: 25
#2Beth Stuart (University of Southampton)H-Index: 20
Last.Paul Little (University of Southampton)H-Index: 55
view all 11 authors...
Background There are more than 1500 UK health helplines in operation, yet we have scant knowledge about the resources in place to support the seeking and delivering of cancer-related telephone help and support. This research aimed to identify and describe cancer and cancer-related helpline service provision: the number of helplines available, the variety of services provided, and the accessibility of those services. Method This study used online national questionnaire survey sent to 95 cancer an...
1 CitationsSource
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