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Xiaohong Ma
Sichuan University
PsychiatryPsychologyPopulationGeneticsSchizophrenia
136Publications
23H-index
1,767Citations
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Publications 139
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#1Hua Yu (Sichuan University)H-Index: 3
#2Mingli Li (Sichuan University)H-Index: 14
Last. Wei Deng (Sichuan University)H-Index: 27
view all 13 authors...
Abstract Objective The frontal-limbic circuit is hypothesized as sub-serving emotional regulation. We performed whole brain resting-state functional connectivity (rs-FC) analysis by studying the key hubs of frontal-limbic circuit: anterior cingulate cortex (ACC), bilateral insula subregions, bilateral amygdala (Amy) as seeds, separately, to discriminate bipolar depression (BipD) from unipolar depression (UniD). Methods We compared seed-based rs-FC of the frontal-limbic seeds with whole brain amo...
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#1Shile Qi (Georgia Institute of Technology)H-Index: 5
#2Juan R. Bustillo (UNM: University of New Mexico)H-Index: 44
Last. Xiao Yang (Sichuan University)H-Index: 7
view all 15 authors...
Schizophrenia (SZ) is frequently concurrent with substance use, depressive symptoms, social communication and attention deficits. However, the relationship between common brain networks (e.g., SZ vs. substance use, SZ vs. depression, SZ vs. developmental disorders) with SZ on specific symptoms and cognition is unclear. Symptom scores were used as a reference to guide fMRI-sMRI fusion for SZ (n = 94), substance use with drinking (n = 313), smoking (n = 104), major depressive disorder (MDD, n = 26...
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#1Jianlong Zhao (CAS: Chinese Academy of Sciences)H-Index: 21
#2Jinjie Huang (Harbin University of Science and Technology)
Last. Vince D. Calhoun (Georgia Institute of Technology)H-Index: 93
view all 11 authors...
Abstract As a popular deep learning method, generative adversarial networks (GAN) have achieved outstanding performance in multiple classifications and segmentation tasks. However, the application of GANs to fMRI data is relatively rare. In this work, we proposed a functional network connectivity (FNC) based GAN for classifying psychotic disorders from healthy controls (HCs), in which FNC matrices were calculated by correlation of time courses derived from non-artefactual fMRI independent compon...
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#1Li Yao (Sichuan University)H-Index: 10
#2Fei Li (Sichuan University)H-Index: 11
Last. Xiao Yang (Sichuan University)H-Index: 7
view all 18 authors...
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#1Wei Wei (Sichuan University)H-Index: 1
#1Wei Wei (Sichuan University)H-Index: 57
Last. Zhang Nanyin (PSU: Pennsylvania State University)H-Index: 26
view all 11 authors...
Myelination is key to effective message passing in the central nervous system and is likely linked to the pathogenesis of schizophrenia (SZ). Emerging evidence indicates that a large portion of intracortical myelin insulates inhibitory interneurons that are highly relevant to pathogenesis of schizophrenia. Here for the first time, we characterized intracortical myelination across the entire cortical surface in first-episode treatment-naive patients with schizophrenia (FES) using T1w/T2w ratio of...
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#1Sugai Liang (Sichuan University)H-Index: 4
#2Wei Deng (Sichuan University)H-Index: 27
Last. Yajing Meng (Sichuan University)H-Index: 10
view all 15 authors...
Abstract Background Posterior cingulate cortex (PCC) is a key aspect of the default mode network (DMN). Aberrant PCC functional connectivity (FC) is implicated in schizophrenia, but the potential for PCC related changes as biological classifier of schizophrenia has not yet been evaluated. Methods We conducted a data-driven approach using resting-state functional MRI data to explore differences in PCC-based region- and voxel-wise FC patterns, to distinguish between patients with first-episode sch...
1 CitationsSource
#1Sugai Liang (Sichuan University)H-Index: 4
#2Wei Deng (Sichuan University)H-Index: 27
Last. Yajing Meng (Sichuan University)H-Index: 10
view all 15 authors...
Abstract Background Posterior cingulate cortex (PCC) is a key aspect of the default mode network (DMN). Aberrant PCC functional connectivity (FC) is implicated in schizophrenia, but the potential for PCC related changes as biological classifier of schizophrenia has not yet been evaluated. Methods We conducted a data-driven approach using resting-state functional MRI data to explore differences in PCC-based region- and voxel-wise FC patterns, to distinguish between patients with first-episode sch...
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#1Yamin ZhangH-Index: 2
#2Qiang WangH-Index: 27
Last. Tianlan LuH-Index: 16
view all 35 authors...
OBJECTIVE: To compare longitudinal metabolic effects of 7 antipsychotics, including body mass index (BMI), waist circumference (WC), blood pressure (BP), glucose, triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C); to investigate risk factors for metabolic syndrome (MetS); and to make recommendations on frequency and timing of monitoring metabolic measurements. METHODS: This randomized, open-label, pharmacologic trial was conducted a...
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#1Rong-Jun Ni (Sichuan University)H-Index: 6
#2Yang Tian (Sichuan University)H-Index: 1
Last. Tao Li (Sichuan University)H-Index: 46
view all 8 authors...
Adult male tree shrews vigorously defend against intruding male conspecifics. However, the characteristics of social behavior have not been entirely explored in these males. In this study, male wild-type tree shrews ( Tupaia belangeri chinensis) and C57BL/6J mice were first allowed to familiarize themselves with an open-field apparatus. The tree shrews exhibited a short duration of movement (moving) in the novel environment, whereas the mice exhibited a long duration of movement. In the 30 min s...
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#1Yamin ZhangH-Index: 2
#2Mingli LiH-Index: 14
Last. Tao LiH-Index: 46
view all 11 authors...
Background Major depressive disorder (MDD) is a leading cause of disability worldwide and influenced by both environmental and genetic factors. Genetic studies of MDD have focused on common variants and have been constrained by the heterogeneity of clinical symptoms. Methods We sequenced the exome of 77 cases and 245 controls of Han Chinese ancestry and scanned their brain. Burden tests of rare variants were performed first to explore the association between genes/pathways and MDD. Secondly, par...
1 CitationsSource
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